Charles River Laboratories International (FRA:RV6) Cyclically Adjusted PB Ratio: 4.83 (As of Aug. 05, 2026) — 23% Below Median

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FRA:RV6 Charles River Laboratories International Inc FRA:RV6
71 GF Score
Price €200.40
GF Value €157.71
Valuation Modestly Overvalued
! 8 Warning Signs
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What is Charles River Laboratories International Cyclically Adjusted PB Ratio?

Charles River Laboratories International FRA:RV6 -0.74% 71 Cyclically Adjusted PB Ratio is 4.83 as of Aug. 05, 2026, which is 23% below its 10-year median of 6.24. GuruFocus rates FRA:RV6 with a GF Score™ of 71/100 and a GF Value™ of €157.71 (Modestly Overvalued). The stock has 8 warning signs investors should review. Among 131 Medical Diagnostics & Research companies, Charles River Laboratories International ranks worse than 79.39% on this metric.

As of today (2026-08-05), Charles River Laboratories International's current share price is €200.40. Charles River Laboratories International's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was €41.47. Charles River Laboratories International's Cyclically Adjusted PB Ratio for today is 4.83.

The historical rank and industry rank for Charles River Laboratories International's Cyclically Adjusted PB Ratio or its related term are showing as below:

FRA:RV6' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 2.21   Med: 6.24   Max: 19.58
Current: 4.51

During the past years, Charles River Laboratories International's highest Cyclically Adjusted PB Ratio was 19.58. The lowest was 2.21. And the median was 6.24.

FRA:RV6's Cyclically Adjusted PB Ratio is ranked worse than
79.39% of 131 companies
in the Medical Diagnostics & Research industry
Industry Median: 1.75 vs FRA:RV6: 4.51

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Charles River Laboratories International's adjusted book value per share data for the three months ended in Mar. 2026 was €52.808. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is €41.47 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Charles River Laboratories International  (FRA:RV6) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Charles River Laboratories International Cyclically Adjusted PB Ratio Related Terms


Charles River Laboratories International Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Charles River Laboratories International's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Charles River Laboratories International Cyclically Adjusted PB Ratio Chart

Charles River Laboratories International Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 14.59 6.95 6.36 4.25 4.05

Charles River Laboratories International Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 3.33 3.24 3.24 4.05 3.37

FRA:RV6 vs RVTY, ICLR, QGEN: Cyclically Adjusted PB Ratio Comparison

For the Diagnostics & Research subindustry, Charles River Laboratories International's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Charles River Laboratories International Cyclically Adjusted PB Ratio vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, Charles River Laboratories International's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Charles River Laboratories International's Cyclically Adjusted PB Ratio falls into.


FRA:RV6
71GF Score
Charles River Laboratories International Inc FRA:RV6
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Charles River Laboratories International Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Charles River Laboratories International's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=200.40/41.47
=4.83

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Charles River Laboratories International's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Charles River Laboratories International's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=52.808/330.2130*330.2130
=52.808

Current CPI (Mar. 2026) = 330.2130.

Charles River Laboratories International Quarterly Data

Book Value per Share CPI Adj_Book
201606 15.649 241.018 21.440
201609 16.342 241.428 22.352
201612 16.748 241.432 22.907
201703 17.203 243.801 23.300
201706 18.020 244.955 24.292
201709 18.110 246.819 24.229
201712 18.630 246.524 24.954
201803 19.297 249.554 25.534
201806 21.078 251.989 27.621
201809 22.329 252.439 29.208
201812 24.019 251.233 31.570
201903 25.383 254.202 32.973
201906 26.389 256.143 34.020
201909 28.489 256.759 36.639
201912 30.062 256.974 38.630
202003 30.211 258.115 38.650
202006 31.341 257.797 40.145
202009 32.381 260.280 41.081
202012 34.927 260.474 44.278
202103 36.532 264.877 45.543
202106 38.187 271.696 46.412
202109 40.876 274.310 49.206
202112 44.440 278.802 52.635
202203 46.654 287.504 53.584
202206 49.247 296.311 54.882
202209 52.148 296.808 58.017
202212 55.151 296.797 61.360
202303 56.728 301.836 62.061
202306 58.544 305.109 63.361
202309 60.389 307.789 64.789
202312 64.248 306.746 69.163
202403 65.019 312.332 68.741
202406 67.007 314.175 70.428
202409 66.645 315.301 69.797
202412 64.640 315.605 67.632
202503 60.159 319.799 62.118
202506 59.081 322.561 60.483
202509 58.954 324.800 59.937
202512 54.912 324.054 55.956
202603 52.808 330.213 52.808

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 4.83 mean?
Charles River Laboratories International (FRA:RV6) has a Cyclically Adjusted PB Ratio of 4.83 as of Aug. 05, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Charles River Laboratories International and its competitors. This is 23% below median its historical median of 6.24. Over the past decade, Charles River Laboratories International's Cyclically Adjusted PB Ratio has ranged from 2.21 to 19.58. According to the industry distribution chart, Charles River Laboratories International ranks #104 out of 131 companies in the Medical Diagnostics & Research industry, placing it in the top 79.4%.
Is Charles River Laboratories International's Cyclically Adjusted PB Ratio too high?
Charles River Laboratories International's current Cyclically Adjusted PB Ratio of 4.83 is 23% below median its 10-year median of 6.24. Over the past 10 years, this metric has ranged from a low of 2.21 to a high of 19.58. The Medical Diagnostics & Research industry median Cyclically Adjusted PB Ratio is 1.75. Charles River Laboratories International's value of 4.83 is 176% above this industry median. Based on the distribution chart, Charles River Laboratories International ranks #104 out of 131 companies in the Medical Diagnostics & Research industry, which is in the bottom quartile relative to peers. Overall, Charles River Laboratories International has a GF Score™ of 71/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Charles River Laboratories International's Cyclically Adjusted PB Ratio compare to RVTY and ICLR?
According to the Medical Diagnostics & Research industry distribution chart, Charles River Laboratories International ranks #104 out of 131 companies for Cyclically Adjusted PB Ratio. This places Charles River Laboratories International in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.75. Charles River Laboratories International's value of 4.83 is 176% above this benchmark. Historically, Charles River Laboratories International's own Cyclically Adjusted PB Ratio has ranged from 2.21 to 19.58 over the past decade. While the company's 10-year median is 6.24 vs. the industry median of 1.75, Charles River Laboratories International has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Medical Diagnostics & Research company?
The median Cyclically Adjusted PB Ratio among Medical Diagnostics & Research companies is 1.75, based on 131 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Charles River Laboratories International's current Cyclically Adjusted PB Ratio of 4.83 is 176% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Charles River Laboratories International and its competitors. For the Medical Diagnostics & Research industry, the median Cyclically Adjusted PB Ratio is 1.75 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Charles River Laboratories International's current Cyclically Adjusted PB Ratio is 4.83, which is 23% below median its own 10-year median of 6.24. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Charles River Laboratories International stock overvalued right now?
Based on GuruFocus' analysis, Charles River Laboratories International (FRA:RV6) is currently considered Modestly Overvalued. The stock's GF Value™ is €157.71, compared to a current price of €200.40 — trading 27.1% above its estimated fair value. The current Cyclically Adjusted PB Ratio is 4.83, which is 23% below median its 10-year median of 6.24 and 176% above the Medical Diagnostics & Research industry median of 1.75. Charles River Laboratories International's overall GF Score™ is 71/100 with 8 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Charles River Laboratories International (FRA:RV6), the current Cyclically Adjusted PB Ratio is 4.83 as of Aug. 05, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Charles River Laboratories International (FRA:RV6) Overvalued in 2026?

Based on GuruFocus' analysis, Charles River Laboratories International stock appears to be overvalued. The current stock price of €200.40 is trading 27.1% above its estimated GF Value™ of €157.71. GuruFocus considers Charles River Laboratories International to be Modestly Overvalued.

Key valuation signals for FRA:RV6:

  • Cyclically Adjusted PB Ratio: 4.83 (23% below median its 10-year median of 6.24)
  • GF Value™: €157.71 vs. price of €200.40 (27.1% above fair value)
  • GF Score™: 71/100 with 8 warning signs
  • Industry Position: 176% above the Medical Diagnostics & Research median (#104 of 131)

No single metric tells the full story. See the FRA:RV6 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Charles River Laboratories International Business Description

Other Exchanges CRL:USA
Address 251 Ballardvale Street, Wilmington, MA, USA, 01887
Charles River Laboratories was founded in 1947 and is a leading provider of drug discovery and development services. The company's research model & services segment is the leading provider of animal models for laboratory testing, which breeds and delivers animal research models with specific genetic characteristics for preclinical studies around the world. The discovery & safety assessment segment includes services required to take a drug through the early development process, including discovery services. The manufacturing support segment includes microbial solutions, which provides in vitro (non-animal) testing products, biologics testing services, and avian vaccine services.
71GF Score

Get the complete analysis for FRA:RV6

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€200.40
Price
€157.71
GF Value