United Therapeutics (FRA:UTH) Cyclically Adjusted PB Ratio: 4.80 (As of Aug. 06, 2026) — 20% Above Median

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FRA:UTH United Therapeutics Corp FRA:UTH
83 GF Score
Price €446.10
GF Value €367.50
Valuation Modestly Overvalued
! 3 Warning Signs
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What is United Therapeutics Cyclically Adjusted PB Ratio?

United Therapeutics FRA:UTH +0.13% 83 Cyclically Adjusted PB Ratio is 4.80 as of Aug. 06, 2026, which is 20% above its 10-year median of 4.01. GuruFocus rates FRA:UTH with a GF Score™ of 83/100 and a GF Value™ of €367.50 (Modestly Overvalued). The stock has 3 warning signs investors should review. Among 737 Drug Manufacturers companies, United Therapeutics ranks worse than 83.04% on this metric.

As of today (2026-08-06), United Therapeutics's current share price is €446.10. United Therapeutics's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 was €92.85. United Therapeutics's Cyclically Adjusted PB Ratio for today is 4.80.

The historical rank and industry rank for United Therapeutics's Cyclically Adjusted PB Ratio or its related term are showing as below:

FRA:UTH' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 2.27   Med: 4.01   Max: 8.18
Current: 4.9

During the past years, United Therapeutics's highest Cyclically Adjusted PB Ratio was 8.18. The lowest was 2.27. And the median was 4.01.

FRA:UTH's Cyclically Adjusted PB Ratio is ranked worse than
83.04% of 737 companies
in the Drug Manufacturers industry
Industry Median: 1.77 vs FRA:UTH: 4.90

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

United Therapeutics's adjusted book value per share data for the three months ended in Jun. 2026 was €130.880. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is €92.85 for the trailing ten years ended in Jun. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


United Therapeutics  (FRA:UTH) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


United Therapeutics Cyclically Adjusted PB Ratio Related Terms


United Therapeutics Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for United Therapeutics's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

United Therapeutics Cyclically Adjusted PB Ratio Chart

United Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 4.24 4.52 3.04 4.19 4.96

United Therapeutics Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 3.11 4.38 4.96 5.79 5.12

FRA:UTH vs VTRS, NBIX, ZTS: Cyclically Adjusted PB Ratio Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, United Therapeutics's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


United Therapeutics Cyclically Adjusted PB Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, United Therapeutics's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where United Therapeutics's Cyclically Adjusted PB Ratio falls into.


FRA:UTH
83GF Score
United Therapeutics Corp FRA:UTH
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

United Therapeutics Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

United Therapeutics's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=446.10/92.85
=4.80

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

United Therapeutics's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 is calculated as:

For example, United Therapeutics's adjusted Book Value per Share data for the three months ended in Jun. 2026 was:

Adj_Book=Book Value per Share/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=130.88/333.9520*333.9520
=130.880

Current CPI (Jun. 2026) = 333.9520.

United Therapeutics Quarterly Data

Book Value per Share CPI Adj_Book
201609 38.401 241.428 53.118
201612 40.847 241.432 56.500
201703 42.862 243.801 58.711
201706 36.392 244.955 49.614
201709 40.194 246.819 54.383
201712 41.074 246.524 55.641
201803 44.239 249.554 59.200
201806 50.414 251.989 66.812
201809 52.947 252.439 70.044
201812 56.235 251.233 74.750
201903 46.850 254.202 61.548
201906 51.637 256.143 67.323
201909 56.196 256.759 73.091
201912 57.021 256.974 74.102
202003 60.643 258.115 78.461
202006 61.934 257.797 80.230
202009 62.722 260.280 80.475
202012 62.706 260.474 80.395
202103 64.617 264.877 81.468
202106 67.292 271.696 82.711
202109 72.305 274.310 88.026
202112 77.672 278.802 93.036
202203 83.734 287.504 97.262
202206 89.804 296.311 101.212
202209 101.131 296.808 113.787
202212 98.368 296.797 110.682
202303 102.466 301.836 113.369
202306 106.460 305.109 116.524
202309 113.923 307.789 123.607
202312 116.666 306.746 127.013
202403 111.097 312.332 118.787
202406 119.146 314.175 126.646
202409 123.205 315.301 130.493
202412 137.272 315.605 145.252
202503 139.693 319.799 145.875
202506 137.554 322.561 142.412
202509 130.873 324.800 134.561
202512 138.857 324.054 143.098
202603 121.085 330.213 122.456
202606 130.880 333.952 130.880

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 4.80 mean?
United Therapeutics (FRA:UTH) has a Cyclically Adjusted PB Ratio of 4.80 as of Aug. 06, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on United Therapeutics and its competitors. This is 20% above median its historical median of 4.01. Over the past decade, United Therapeutics' Cyclically Adjusted PB Ratio has ranged from 2.27 to 8.18. According to the industry distribution chart, United Therapeutics ranks #612 out of 737 companies in the Drug Manufacturers industry, placing it in the top 83%.
Is United Therapeutics' Cyclically Adjusted PB Ratio too high?
United Therapeutics' current Cyclically Adjusted PB Ratio of 4.80 is 20% above median its 10-year median of 4.01. Over the past 10 years, this metric has ranged from a low of 2.27 to a high of 8.18. The Drug Manufacturers industry median Cyclically Adjusted PB Ratio is 1.77. United Therapeutics' value of 4.80 is 171.2% above this industry median. Based on the distribution chart, United Therapeutics ranks #612 out of 737 companies in the Drug Manufacturers industry, which is in the bottom quartile relative to peers. Overall, United Therapeutics has a GF Score™ of 83/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does United Therapeutics' Cyclically Adjusted PB Ratio compare to VTRS and NBIX?
According to the Drug Manufacturers industry distribution chart, United Therapeutics ranks #612 out of 737 companies for Cyclically Adjusted PB Ratio. This places United Therapeutics in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.77. United Therapeutics' value of 4.80 is 171.2% above this benchmark. Historically, United Therapeutics' own Cyclically Adjusted PB Ratio has ranged from 2.27 to 8.18 over the past decade. While the company's 10-year median is 4.01 vs. the industry median of 1.77, United Therapeutics has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Drug Manufacturers company?
The median Cyclically Adjusted PB Ratio among Drug Manufacturers companies is 1.77, based on 737 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. United Therapeutics's current Cyclically Adjusted PB Ratio of 4.80 is 171.2% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on United Therapeutics and its competitors. For the Drug Manufacturers industry, the median Cyclically Adjusted PB Ratio is 1.77 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. United Therapeutics's current Cyclically Adjusted PB Ratio is 4.80, which is 20% above median its own 10-year median of 4.01. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is United Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, United Therapeutics (FRA:UTH) is currently considered Modestly Overvalued. The stock's GF Value™ is €367.50, compared to a current price of €446.10 — trading 21.4% above its estimated fair value. The current Cyclically Adjusted PB Ratio is 4.80, which is 20% above median its 10-year median of 4.01 and 171.2% above the Drug Manufacturers industry median of 1.77. United Therapeutics' overall GF Score™ is 83/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For United Therapeutics (FRA:UTH), the current Cyclically Adjusted PB Ratio is 4.80 as of Aug. 06, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is United Therapeutics (FRA:UTH) Overvalued in 2026?

Based on GuruFocus' analysis, United Therapeutics stock appears to be overvalued. The current stock price of €446.10 is trading 21.4% above its estimated GF Value™ of €367.50. GuruFocus considers United Therapeutics to be Modestly Overvalued.

Key valuation signals for FRA:UTH:

  • Cyclically Adjusted PB Ratio: 4.80 (20% above median its 10-year median of 4.01)
  • GF Value™: €367.50 vs. price of €446.10 (21.4% above fair value)
  • GF Score™: 83/100 with 3 warning signs
  • Industry Position: 171.2% above the Drug Manufacturers median (#612 of 737)

No single metric tells the full story. See the FRA:UTH stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


United Therapeutics Business Description

Other Exchanges UTHR:USAU2TH34:Brazil
Address 1000 Spring Street, Silver Spring, MD, USA, 20910
United Therapeutics Corp specializes in drug development for pulmonary arterial hypertension (PAH), a rare and progressive disease marked by abnormally high blood pressure in the arteries of the lungs. The company's therapies for PAH largely focus on the prostacyclin pathway, and many of its treatments are based on the same molecule, treprostinil. The company markets and sells the following commercial therapies in the United States to treat PAH: Tyvaso DPI (treprostinil) Inhalation Powder, Remodulin Injection, Orenitram (treprostinil) Extended-Release Tablets, Adcirca (tadalafil) Tablets, and Unituxin. It derives maximum revenue from the sale of Tyvaso DPI. Geographically, the company operates in United States and Rest of the World, of which United States generates majority of the revenue.
83GF Score

Get the complete analysis for FRA:UTH

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€446.10
Price
€367.50
GF Value