Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.
As of today (2026-08-03), Hologic's current share price is $76.01. Hologic's Cyclically Adjusted Book per Share for the quarter that ended in Dec. 2025 was $16.58. Hologic's Cyclically Adjusted PB Ratio for today is 4.58.
The historical rank and industry rank for Hologic's Cyclically Adjusted PB Ratio or its related term are showing as below:
HOLX'
s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 3.09 Med: 4.98 Max: 8.37
Current: 4.59
During the past years, Hologic's highest Cyclically Adjusted PB Ratio was 8.37. The lowest was 3.09. And the median was 4.98.
HOLX's Cyclically Adjusted PB Ratio is not ranked
in the Medical Devices & Instruments industry.
Industry Median: 1.78
vs HOLX: 4.59
The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.
Hologic's adjusted book value per share data for the three months ended in Dec. 2025 was $23.514. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $16.58 for the trailing ten years ended in Dec. 2025.
Shiller PE for Stocks: The True Measure of Stock Valuation
Hologic (NAS:HOLX) Cyclically Adjusted PB Ratio Explanation
Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.
If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.
Hologic Cyclically Adjusted PB Ratio Related Terms
Hologic Cyclically Adjusted PB Ratio Historical Data
* Premium members only.
The historical data trend for Hologic's Cyclically Adjusted PB Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
HOLX vs WST, COO, ALGN: Cyclically Adjusted PB Ratio Comparison
For the Medical Instruments & Supplies subindustry, Hologic's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Hologic Cyclically Adjusted PB Ratio vs Medical Devices & Instruments Industry
For the Medical Devices & Instruments industry and Healthcare sector, Hologic's Cyclically Adjusted PB Ratio distribution charts can be found below:
* The bar in red indicates where Hologic's Cyclically Adjusted PB Ratio falls into.
Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.
The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.
Hologic's Cyclically Adjusted PB Ratio for today is calculated as
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.
What does a Cyclically Adjusted PB Ratio of 4.58 mean?
Hologic (HOLX) has a Cyclically Adjusted PB Ratio of 4.58 as of Aug. 03, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Hologic and its competitors. This is near median its historical median of 4.98. Over the past decade, Hologic's Cyclically Adjusted PB Ratio has ranged from 3.09 to 8.37.
Is Hologic's Cyclically Adjusted PB Ratio too high?
Hologic's current Cyclically Adjusted PB Ratio of 4.58 is near median its 10-year median of 4.98. Over the past 10 years, this metric has ranged from a low of 3.09 to a high of 8.37. The Medical Devices & Instruments industry median Cyclically Adjusted PB Ratio is 1.78. Hologic's value of 4.58 is 157.3% above this industry median. Overall, Hologic has a GF Score™ of 57/100, reflecting its overall financial health beyond just this single metric.
How does Hologic's Cyclically Adjusted PB Ratio compare to WST and COO?
Hologic's Cyclically Adjusted PB Ratio of 4.58 can be compared against companies in the Medical Devices & Instruments industry. The industry median Cyclically Adjusted PB Ratio is 1.78. Hologic's value of 4.58 is 157.3% above this benchmark. Historically, Hologic's own Cyclically Adjusted PB Ratio has ranged from 3.09 to 8.37 over the past decade. While the company's 10-year median is 4.98 vs. the industry median of 1.78, Hologic has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Medical Devices & Instruments company?
The median Cyclically Adjusted PB Ratio among Medical Devices & Instruments companies is 1.78, based on 521 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Hologic's current Cyclically Adjusted PB Ratio of 4.58 is 157.3% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Hologic and its competitors. For the Medical Devices & Instruments industry, the median Cyclically Adjusted PB Ratio is 1.78 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Hologic's current Cyclically Adjusted PB Ratio is 4.58, which is near median its own 10-year median of 4.98. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Hologic stock overvalued right now?
Hologic (HOLX) has a current Cyclically Adjusted PB Ratio of 4.58. The stock's GF Value™ is $82.05, compared to a current price of $76.01 — trading 7.4% below its estimated fair value. The current Cyclically Adjusted PB Ratio is 4.58, which is near median its 10-year median of 4.98 and 157.3% above the Medical Devices & Instruments industry median of 1.78. Hologic's overall GF Score™ is 57/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Hologic (HOLX), the current Cyclically Adjusted PB Ratio is 4.58 as of Aug. 03, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Hologic (HOLX) Overvalued in 2026?
Based on GuruFocus' analysis, Hologic stock appears to be undervalued.
The current stock price of $76.01 is trading 7.4% below its estimated GF Value™ of $82.05.
Key valuation signals for HOLX:
Cyclically Adjusted PB Ratio: 4.58 (near median its 10-year median of 4.98)
GF Value™: $82.05 vs. price of $76.01 (7.4% below fair value)
Industry Position: 157.3% above the Medical Devices & Instruments median
No single metric tells the full story. See the HOLX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Hologic manufactures proprietary products for the healthcare needs of women. The company operates in four segments: diagnostics (44% of total sales), breast health (38%), surgical (16%), and skeletal health (2%). While the company traditionally focused on breast health, the acquisition of Gen-Probe put greater emphasis on commercial diagnostics. The United States accounts for the largest portion of the firm's revenue (69%), followed by Europe (20%), Asia (8%), and other international markets (3%). Hologic is headquartered in Bedford, Massachusetts.
57GF Score
Get the complete analysis for HOLX
Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
Quick Browse
Personalize
Premium Gurus 
Create New Portfolio
HOLX has been successfully added to your 
