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Insight Molecular DiagnosticsIMDX +16.13%49 Cyclically Adjusted PB Ratio is 0.48 as of Aug. 17, 2026, which is 41% above its 10-year median of 0.34. GuruFocus rates IMDX with a GF Score™ of 49/100 and a GF Value™ of $1.08 (Significantly Overvalued). The stock has 7 warning signs investors should review. Among 130 Medical Diagnostics & Research companies, Insight Molecular Diagnostics ranks better than 80% on this metric.
The historical rank and industry rank for Insight Molecular Diagnostics's Cyclically Adjusted PB Ratio or its related term are showing as below:
IMDX'
s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.2 Med: 0.34 Max: 0.82
Current: 0.48
During the past years, Insight Molecular Diagnostics's highest Cyclically Adjusted PB Ratio was 0.82. The lowest was 0.20. And the median was 0.34.
IMDX's Cyclically Adjusted PB Ratio is ranked better than 80% of 130
companies
in the Medical Diagnostics & Research industry
Industry Median: 1.815
vs IMDX: 0.48
The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.
Insight Molecular Diagnostics's adjusted book value per share data for the three months ended in Jun. 2026 was $-0.653. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $8.98 for the trailing ten years ended in Jun. 2026.
Shiller PE for Stocks: The True Measure of Stock Valuation
Insight Molecular Diagnostics (NAS:IMDX) Cyclically Adjusted PB Ratio Explanation
Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.
If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.
Insight Molecular Diagnostics Cyclically Adjusted PB Ratio Related Terms
Insight Molecular Diagnostics Cyclically Adjusted PB Ratio Historical Data
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Insight Molecular Diagnostics Cyclically Adjusted PB Ratio Chart
IMDX vs XGN, BNR, BDSX: Cyclically Adjusted PB Ratio Comparison
For the Diagnostics & Research subindustry, Insight Molecular Diagnostics's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Insight Molecular Diagnostics Cyclically Adjusted PB Ratio vs Medical Diagnostics & Research Industry
For the Medical Diagnostics & Research industry and Healthcare sector, Insight Molecular Diagnostics's Cyclically Adjusted PB Ratio distribution charts can be found below:
* The bar in red indicates where Insight Molecular Diagnostics's Cyclically Adjusted PB Ratio falls into.
Insight Molecular Diagnostics Cyclically Adjusted PB Ratio Calculation
Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.
The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.
What does a Cyclically Adjusted PB Ratio of 0.48 mean?
Insight Molecular Diagnostics (IMDX) has a Cyclically Adjusted PB Ratio of 0.48 as of Aug. 17, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Insight Molecular Diagnostics and its competitors. This is 41% above median its historical median of 0.34. Over the past decade, Insight Molecular Diagnostics' Cyclically Adjusted PB Ratio has ranged from 0.20 to 0.82. According to the industry distribution chart, Insight Molecular Diagnostics ranks #26 out of 130 companies in the Medical Diagnostics & Research industry, placing it in the top 20%.
Is Insight Molecular Diagnostics' Cyclically Adjusted PB Ratio too high?
Insight Molecular Diagnostics' current Cyclically Adjusted PB Ratio of 0.48 is 41% above median its 10-year median of 0.34. Over the past 10 years, this metric has ranged from a low of 0.20 to a high of 0.82. The Medical Diagnostics & Research industry median Cyclically Adjusted PB Ratio is 1.82. Insight Molecular Diagnostics' value of 0.48 is 73.6% below this industry median. Based on the distribution chart, Insight Molecular Diagnostics ranks #26 out of 130 companies in the Medical Diagnostics & Research industry, which is in the top quartile — a strong position relative to peers. Overall, Insight Molecular Diagnostics has a GF Score™ of 49/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Insight Molecular Diagnostics' Cyclically Adjusted PB Ratio compare to XGN and BNR?
According to the Medical Diagnostics & Research industry distribution chart, Insight Molecular Diagnostics ranks #26 out of 130 companies for Cyclically Adjusted PB Ratio. This places Insight Molecular Diagnostics in the top 20% of its industry — outperforming the majority of peers. The industry median Cyclically Adjusted PB Ratio is 1.82. Insight Molecular Diagnostics' value of 0.48 is 73.6% below this benchmark. Historically, Insight Molecular Diagnostics' own Cyclically Adjusted PB Ratio has ranged from 0.20 to 0.82 over the past decade. While the company's 10-year median is 0.34 vs. the industry median of 1.82, Insight Molecular Diagnostics has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Medical Diagnostics & Research company?
The median Cyclically Adjusted PB Ratio among Medical Diagnostics & Research companies is 1.82, based on 130 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Insight Molecular Diagnostics's current Cyclically Adjusted PB Ratio of 0.48 is 73.6% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Insight Molecular Diagnostics and its competitors. For the Medical Diagnostics & Research industry, the median Cyclically Adjusted PB Ratio is 1.82 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Insight Molecular Diagnostics's current Cyclically Adjusted PB Ratio is 0.48, which is 41% above median its own 10-year median of 0.34. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Insight Molecular Diagnostics stock overvalued right now?
Based on GuruFocus' analysis, Insight Molecular Diagnostics (IMDX) is currently considered Significantly Overvalued. The stock's GF Value™ is $1.08, compared to a current price of $4.35 — trading 302.8% above its estimated fair value. The current Cyclically Adjusted PB Ratio is 0.48, which is 41% above median its 10-year median of 0.34 and 73.6% below the Medical Diagnostics & Research industry median of 1.82. Insight Molecular Diagnostics' overall GF Score™ is 49/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Insight Molecular Diagnostics (IMDX), the current Cyclically Adjusted PB Ratio is 0.48 as of Aug. 17, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Insight Molecular Diagnostics (IMDX) Overvalued in 2026?
Based on GuruFocus' analysis, Insight Molecular Diagnostics stock appears to be overvalued.
The current stock price of $4.35 is trading 302.8% above its estimated GF Value™ of $1.08.
GuruFocus considers Insight Molecular Diagnostics to be Significantly Overvalued.
Key valuation signals for IMDX:
Cyclically Adjusted PB Ratio: 0.48 (41% above median its 10-year median of 0.34)
GF Value™: $1.08 vs. price of $4.35 (302.8% above fair value)
Industry Position: 73.6% below the Medical Diagnostics & Research median (#26 of 130)
No single metric tells the full story. See the IMDX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Insight Molecular Diagnostics Inc is a pioneering diagnostics technology company whose mission is to democratize access to novel molecular diagnostic testing to improve patient outcomes. The Company's flagship technology quantifies a molecular biomarker known as donor-derived cell-free DNA (dd-cfDNA). It is also in the process of rebranding its RUO test kit, GraftAssure, as GraftAssureIQ, and rebranding its future in-vitro diagnostic (IVD) test kit as GraftAssureDx. The company geographically operates in the United States, the United Kingdom, Europe, and the Asia-Pacific regions, with maximum revenue generated from the USA.
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