IVRO (Invitro International) Cyclically Adjusted PB Ratio: 0.07 (As of Aug. 03, 2026) — 22% Below Median

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Director of Data and Quant Analytics at GuruFocus
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Founder & CEO of GuruFocus
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What is Invitro International Cyclically Adjusted PB Ratio?

Invitro International IVRO +1.33% Cyclically Adjusted PB Ratio is 0.07 as of Aug. 03, 2026, which is 22% below its 10-year median of 0.09. The stock has 1 warning sign investors should review. Among 131 Medical Diagnostics & Research companies, Invitro International ranks better than 93.89% on this metric.

As of today (2026-08-03), Invitro International's current share price is $0.0679. Invitro International's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was $0.94. Invitro International's Cyclically Adjusted PB Ratio for today is 0.07.

The historical rank and industry rank for Invitro International's Cyclically Adjusted PB Ratio or its related term are showing as below:

IVRO' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.06   Med: 0.09   Max: 0.16
Current: 0.06

During the past years, Invitro International's highest Cyclically Adjusted PB Ratio was 0.16. The lowest was 0.06. And the median was 0.09.

IVRO's Cyclically Adjusted PB Ratio is ranked better than
93.89% of 131 companies
in the Medical Diagnostics & Research industry
Industry Median: 1.75 vs IVRO: 0.06

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Invitro International's adjusted book value per share data for the three months ended in Mar. 2026 was $0.076. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $0.94 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Invitro International  (OTCPK:IVRO) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Invitro International Cyclically Adjusted PB Ratio Related Terms


Invitro International Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Invitro International's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Invitro International Cyclically Adjusted PB Ratio Chart

Invitro International Annual Data
Trend Feb90 Feb91 Sep92 Sep93 Sep94 Sep95 Sep96 Sep24 Sep25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only 0.00 0.00 0.00 0.00 0.00

Invitro International Quarterly Data
Sep94 Dec94 Mar95 Jun95 Sep95 Dec95 Mar96 Jun96 Sep96 Dec96 Mar97 Jun97 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 0.09 0.09

IVRO vs IDTA, PRPH, NSTM: Cyclically Adjusted PB Ratio Comparison

For the Diagnostics & Research subindustry, Invitro International's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Invitro International Cyclically Adjusted PB Ratio vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, Invitro International's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Invitro International's Cyclically Adjusted PB Ratio falls into.



Invitro International Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Invitro International's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=0.0679/0.94
=0.07

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Invitro International's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Invitro International's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=0.076/330.2130*330.2130
=0.076

Current CPI (Mar. 2026) = 330.2130.

Invitro International Quarterly Data

Book Value per Share CPI Adj_Book
198908 0.000 124.600 0.000
198911 0.000 125.900 0.000
199002 -0.088 128.000 -0.227
199005 0.000 129.200 0.000
199008 0.000 131.600 0.000
199011 0.000 133.800 0.000
199102 0.161 134.800 0.394
199105 2.819 135.600 6.865
199108 1.393 136.600 3.367
199112 0.000 137.900 0.000
199203 0.761 139.300 1.804
199206 0.488 140.200 1.149
199209 0.238 141.300 0.556
199212 0.226 141.900 0.526
199303 0.092 143.600 0.212
199306 0.721 144.400 1.649
199309 0.425 145.100 0.967
199312 0.752 145.800 1.703
199403 0.668 147.200 1.499
199406 0.576 148.000 1.285
199409 0.468 149.400 1.034
199412 0.000 149.700 0.000
199503 0.000 151.400 0.000
199506 0.000 152.500 0.000
199509 0.234 153.200 0.504
199512 0.192 153.500 0.413
199603 0.150 155.700 0.318
199606 0.181 156.700 0.381
199609 0.159 157.800 0.333
199612 0.000 158.600 0.000
199703 0.082 160.000 0.169
199706 0.068 160.300 0.140
202406 0.000 314.175 0.000
202409 0.069 315.301 0.072
202412 0.000 315.605 0.000
202503 0.000 319.799 0.000
202506 0.073 322.561 0.075
202509 0.074 324.800 0.075
202512 0.075 324.054 0.076
202603 0.076 330.213 0.076

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 0.07 mean?
Invitro International (IVRO) has a Cyclically Adjusted PB Ratio of 0.07 as of Aug. 03, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Invitro International and its competitors. This is 22% below median its historical median of 0.09. Over the past decade, Invitro International's Cyclically Adjusted PB Ratio has ranged from 0.06 to 0.16. According to the industry distribution chart, Invitro International ranks #8 out of 131 companies in the Medical Diagnostics & Research industry, placing it in the top 6.1%.
Is Invitro International's Cyclically Adjusted PB Ratio too high?
Invitro International's current Cyclically Adjusted PB Ratio of 0.07 is 22% below median its 10-year median of 0.09. Over the past 10 years, this metric has ranged from a low of 0.06 to a high of 0.16. The Medical Diagnostics & Research industry median Cyclically Adjusted PB Ratio is 1.75. Invitro International's value of 0.07 is 96% below this industry median. Based on the distribution chart, Invitro International ranks #8 out of 131 companies in the Medical Diagnostics & Research industry, which is in the top quartile — a strong position relative to peers.
How does Invitro International's Cyclically Adjusted PB Ratio compare to IDTA and PRPH?
According to the Medical Diagnostics & Research industry distribution chart, Invitro International ranks #8 out of 131 companies for Cyclically Adjusted PB Ratio. This places Invitro International in the top 6% of its industry — outperforming the majority of peers. The industry median Cyclically Adjusted PB Ratio is 1.75. Invitro International's value of 0.07 is 96% below this benchmark. Historically, Invitro International's own Cyclically Adjusted PB Ratio has ranged from 0.06 to 0.16 over the past decade. While the company's 10-year median is 0.09 vs. the industry median of 1.75, Invitro International has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Medical Diagnostics & Research company?
The median Cyclically Adjusted PB Ratio among Medical Diagnostics & Research companies is 1.75, based on 131 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Invitro International's current Cyclically Adjusted PB Ratio of 0.07 is 96% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Invitro International and its competitors. For the Medical Diagnostics & Research industry, the median Cyclically Adjusted PB Ratio is 1.75 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Invitro International's current Cyclically Adjusted PB Ratio is 0.07, which is 22% below median its own 10-year median of 0.09. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Invitro International stock overvalued right now?
Based on GuruFocus' analysis, Invitro International (IVRO) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.05, compared to a current price of $0.07 — trading 35.8% above its estimated fair value. The current Cyclically Adjusted PB Ratio is 0.07, which is 22% below median its 10-year median of 0.09 and 96% below the Medical Diagnostics & Research industry median of 1.75. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Invitro International (IVRO), the current Cyclically Adjusted PB Ratio is 0.07 as of Aug. 03, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Invitro International Business Description

Address 330 East Orangethorpe Avenue, Suite D, Placentia, CA, USA, 92870
Invitro International is a provider of non-animal testing methods. The company develops and commercializes test kits and laboratory services. Its testing technologies are designed to produce data regarding corrosivity, or ocular/dermal irritation, which correlate with animal and human test results. Its products and services include Irritection, Corrositex, and Lab Services. The company provides its products to various industries such as cosmetics, personal care, household products, textiles, pharmaceuticals, chemicals, and hazardous waste transportation. The majority of its revenue is generated from the United States and it also exports to other countries.