KHTRF (Knight Therapeutics) Cyclically Adjusted PB Ratio: 1.11 (As of Aug. 05, 2026) — 52% Above Median

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

KHTRF Knight Therapeutics Inc KHTRF
72 GF Score
Price $6.60
GF Value $6.16
Valuation Fairly Valued
! 6 Warning Signs
View Full Analysis

What is Knight Therapeutics Cyclically Adjusted PB Ratio?

Knight Therapeutics KHTRF -1.79% 72 Cyclically Adjusted PB Ratio is 1.11 as of Aug. 05, 2026, which is 52% above its 10-year median of 0.73. GuruFocus rates KHTRF with a GF Score™ of 72/100 and a GF Value™ of $6.16 (Fairly Valued). The stock has 6 warning signs investors should review. Among 737 Drug Manufacturers companies, Knight Therapeutics ranks better than 65.81% on this metric.

As of today (2026-08-05), Knight Therapeutics's current share price is $6.60. Knight Therapeutics's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was $5.94. Knight Therapeutics's Cyclically Adjusted PB Ratio for today is 1.11.

The historical rank and industry rank for Knight Therapeutics's Cyclically Adjusted PB Ratio or its related term are showing as below:

KHTRF' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.58   Med: 0.73   Max: 1.2
Current: 1.18

During the past years, Knight Therapeutics's highest Cyclically Adjusted PB Ratio was 1.20. The lowest was 0.58. And the median was 0.73.

KHTRF's Cyclically Adjusted PB Ratio is ranked better than
65.81% of 737 companies
in the Drug Manufacturers industry
Industry Median: 1.77 vs KHTRF: 1.18

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Knight Therapeutics's adjusted book value per share data for the three months ended in Mar. 2026 was $5.840. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $5.94 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Knight Therapeutics  (OTCPK:KHTRF) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Knight Therapeutics Cyclically Adjusted PB Ratio Related Terms


Knight Therapeutics Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Knight Therapeutics's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Knight Therapeutics Cyclically Adjusted PB Ratio Chart

Knight Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.69 0.67 0.74

Knight Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.76 0.72 0.72 0.74 0.90

KHTRF vs ZTS: Cyclically Adjusted PB Ratio Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Knight Therapeutics's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Knight Therapeutics Cyclically Adjusted PB Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Knight Therapeutics's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Knight Therapeutics's Cyclically Adjusted PB Ratio falls into.


KHTRF
72GF Score
Knight Therapeutics Inc KHTRF
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Knight Therapeutics Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Knight Therapeutics's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=6.60/5.94
=1.11

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Knight Therapeutics's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Knight Therapeutics's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=5.84/132.2623*132.2623
=5.840

Current CPI (Mar. 2026) = 132.2623.

Knight Therapeutics Quarterly Data

Book Value per Share CPI Adj_Book
201606 5.046 102.002 6.543
201609 4.999 101.765 6.497
201612 5.147 101.449 6.710
201703 5.145 102.634 6.630
201706 5.164 103.029 6.629
201709 5.593 103.345 7.158
201712 5.436 103.345 6.957
201803 5.422 105.004 6.830
201806 5.406 105.557 6.774
201809 5.481 105.636 6.863
201812 5.367 105.399 6.735
201903 5.406 106.979 6.684
201906 5.521 107.690 6.781
201909 5.335 107.611 6.557
201912 4.539 107.769 5.571
202003 4.205 107.927 5.153
202006 4.463 108.401 5.445
202009 5.116 108.164 6.256
202012 5.321 108.559 6.483
202103 5.217 110.298 6.256
202106 5.792 111.720 6.857
202109 5.634 112.905 6.600
202112 5.585 113.774 6.493
202203 5.622 117.646 6.321
202206 5.653 120.806 6.189
202209 5.622 120.648 6.163
202212 5.418 120.964 5.924
202303 5.436 122.702 5.860
202306 5.669 124.203 6.037
202309 5.769 125.230 6.093
202312 5.503 125.072 5.819
202403 5.563 126.258 5.828
202406 5.493 127.522 5.697
202409 5.658 127.285 5.879
202412 5.578 127.364 5.793
202503 5.572 129.181 5.705
202506 5.602 129.892 5.704
202509 5.561 130.287 5.645
202512 5.607 130.366 5.689
202603 5.840 132.262 5.840

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 1.11 mean?
Knight Therapeutics (KHTRF) has a Cyclically Adjusted PB Ratio of 1.11 as of Aug. 05, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Knight Therapeutics and its competitors. This is 52% above median its historical median of 0.73. Over the past decade, Knight Therapeutics' Cyclically Adjusted PB Ratio has ranged from 0.58 to 1.20. According to the industry distribution chart, Knight Therapeutics ranks #252 out of 737 companies in the Drug Manufacturers industry, placing it in the top 34.2%.
Is Knight Therapeutics' Cyclically Adjusted PB Ratio too high?
Knight Therapeutics' current Cyclically Adjusted PB Ratio of 1.11 is 52% above median its 10-year median of 0.73. Over the past 10 years, this metric has ranged from a low of 0.58 to a high of 1.20. The Drug Manufacturers industry median Cyclically Adjusted PB Ratio is 1.77. Knight Therapeutics' value of 1.11 is 37.3% below this industry median. Based on the distribution chart, Knight Therapeutics ranks #252 out of 737 companies in the Drug Manufacturers industry, which is above the industry midpoint. Overall, Knight Therapeutics has a GF Score™ of 72/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Knight Therapeutics' Cyclically Adjusted PB Ratio compare to ZTS?
According to the Drug Manufacturers industry distribution chart, Knight Therapeutics ranks #252 out of 737 companies for Cyclically Adjusted PB Ratio. This puts Knight Therapeutics in the upper half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.77. Knight Therapeutics' value of 1.11 is 37.3% below this benchmark. Historically, Knight Therapeutics' own Cyclically Adjusted PB Ratio has ranged from 0.58 to 1.20 over the past decade. While the company's 10-year median is 0.73 vs. the industry median of 1.77, Knight Therapeutics has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Drug Manufacturers company?
The median Cyclically Adjusted PB Ratio among Drug Manufacturers companies is 1.77, based on 737 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Knight Therapeutics's current Cyclically Adjusted PB Ratio of 1.11 is 37.3% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Knight Therapeutics and its competitors. For the Drug Manufacturers industry, the median Cyclically Adjusted PB Ratio is 1.77 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Knight Therapeutics's current Cyclically Adjusted PB Ratio is 1.11, which is 52% above median its own 10-year median of 0.73. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Knight Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Knight Therapeutics (KHTRF) is currently considered Fairly Valued. The stock's GF Value™ is $6.16, compared to a current price of $6.60 — trading 7.1% above its estimated fair value. The current Cyclically Adjusted PB Ratio is 1.11, which is 52% above median its 10-year median of 0.73 and 37.3% below the Drug Manufacturers industry median of 1.77. Knight Therapeutics' overall GF Score™ is 72/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Knight Therapeutics (KHTRF), the current Cyclically Adjusted PB Ratio is 1.11 as of Aug. 05, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Knight Therapeutics (KHTRF) Overvalued in 2026?

Based on GuruFocus' analysis, Knight Therapeutics stock appears to be overvalued. The current stock price of $6.60 is trading 7.1% above its estimated GF Value™ of $6.16. GuruFocus considers Knight Therapeutics to be Fairly Valued.

Key valuation signals for KHTRF:

  • Cyclically Adjusted PB Ratio: 1.11 (52% above median its 10-year median of 0.73)
  • GF Value™: $6.16 vs. price of $6.60 (7.1% above fair value)
  • GF Score™: 72/100 with 6 warning signs
  • Industry Position: 37.3% below the Drug Manufacturers median (#252 of 737)

No single metric tells the full story. See the KHTRF stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Knight Therapeutics Business Description

Other Exchanges GUD:Canada
Address 100 Alexis Nihon Boulevard, Suite 600, Saint-Laurent, QC, CAN, H4M 2P2
Knight Therapeutics Inc is a specialty and generic drug manufacturing company. The company's principal business activity is focused on developing, acquiring, in-licensing, out-licensing, marketing, and commercializing pharmaceuticalproducts. and distributing pharmaceutical products, consumer health products, and medical devices in Canada, Latin America and select international markets. The company finances other life sciences companies across the globe in order to generate interest income, strengthen relationships in the life sciences industry, and to secure product distribution rights. Geographically, the company generates revenue from Brazil, Canada, Colombia, Argentina, Mexico, Rest of LATAM, and Others, with the majority revenue generated from the Brazil region.
72GF Score

Get the complete analysis for KHTRF

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$6.60
Price
$6.16
GF Value