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Kiniksa Pharmaceuticals InternationalKNSA +1.57%50 Cyclically Adjusted PB Ratio is 14.06 as of Jul. 22, 2026, which is 43% above its 10-year median of 9.84. GuruFocus rates KNSA with a GF Score™ of 50/100 and a GF Value™ of $48.87 (Modestly Overvalued). The stock has 4 warning signs investors should review. Among 758 Drug Manufacturers companies, Kiniksa Pharmaceuticals International ranks worse than 94.33% on this metric.
The historical rank and industry rank for Kiniksa Pharmaceuticals International's Cyclically Adjusted PB Ratio or its related term are showing as below:
KNSA'
s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 8.72 Med: 9.84 Max: 13.84
Current: 13.84
During the past 10 years, Kiniksa Pharmaceuticals International's highest Cyclically Adjusted PB Ratio was 13.84. The lowest was 8.72. And the median was 9.84.
KNSA's Cyclically Adjusted PB Ratio is ranked worse than 94.33% of 758
companies
in the Drug Manufacturers industry
Industry Median: 1.855
vs KNSA: 13.84
The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.
Kiniksa Pharmaceuticals International's adjusted book value per share data of for the fiscal year that ended in Dec25 was $7.440. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $4.52 for the trailing ten years ended in Dec25.
Shiller PE for Stocks: The True Measure of Stock Valuation
Kiniksa Pharmaceuticals International (NAS:KNSA) Cyclically Adjusted PB Ratio Explanation
Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.
If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.
Kiniksa Pharmaceuticals International Cyclically Adjusted PB Ratio Related Terms
Kiniksa Pharmaceuticals International Cyclically Adjusted PB Ratio Historical Data
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Kiniksa Pharmaceuticals International Cyclically Adjusted PB Ratio Chart
KNSA vs INDV, AMRX, RGC: Cyclically Adjusted PB Ratio Comparison
For the Drug Manufacturers - Specialty & Generic subindustry, Kiniksa Pharmaceuticals International's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Kiniksa Pharmaceuticals International Cyclically Adjusted PB Ratio vs Drug Manufacturers Industry
For the Drug Manufacturers industry and Healthcare sector, Kiniksa Pharmaceuticals International's Cyclically Adjusted PB Ratio distribution charts can be found below:
* The bar in red indicates where Kiniksa Pharmaceuticals International's Cyclically Adjusted PB Ratio falls into.
Kiniksa Pharmaceuticals International Cyclically Adjusted PB Ratio Calculation
Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.
The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.
What does a Cyclically Adjusted PB Ratio of 14.06 mean?
Kiniksa Pharmaceuticals International (KNSA) has a Cyclically Adjusted PB Ratio of 14.06 as of Jul. 22, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Kiniksa Pharmaceuticals International and its competitors. This is 43% above median its historical median of 9.84. Over the past decade, Kiniksa Pharmaceuticals International's Cyclically Adjusted PB Ratio has ranged from 8.72 to 13.84. According to the industry distribution chart, Kiniksa Pharmaceuticals International ranks #715 out of 758 companies in the Drug Manufacturers industry, placing it in the top 94.3%.
Is Kiniksa Pharmaceuticals International's Cyclically Adjusted PB Ratio too high?
Kiniksa Pharmaceuticals International's current Cyclically Adjusted PB Ratio of 14.06 is 43% above median its 10-year median of 9.84. Over the past 10 years, this metric has ranged from a low of 8.72 to a high of 13.84. The Drug Manufacturers industry median Cyclically Adjusted PB Ratio is 1.86. Kiniksa Pharmaceuticals International's value of 14.06 is 658% above this industry median. Based on the distribution chart, Kiniksa Pharmaceuticals International ranks #715 out of 758 companies in the Drug Manufacturers industry, which is in the bottom quartile relative to peers. Overall, Kiniksa Pharmaceuticals International has a GF Score™ of 50/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Kiniksa Pharmaceuticals International's Cyclically Adjusted PB Ratio compare to INDV and AMRX?
According to the Drug Manufacturers industry distribution chart, Kiniksa Pharmaceuticals International ranks #715 out of 758 companies for Cyclically Adjusted PB Ratio. This places Kiniksa Pharmaceuticals International in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.86. Kiniksa Pharmaceuticals International's value of 14.06 is 658% above this benchmark. Historically, Kiniksa Pharmaceuticals International's own Cyclically Adjusted PB Ratio has ranged from 8.72 to 13.84 over the past decade. While the company's 10-year median is 9.84 vs. the industry median of 1.86, Kiniksa Pharmaceuticals International has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Drug Manufacturers company?
The median Cyclically Adjusted PB Ratio among Drug Manufacturers companies is 1.86, based on 758 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Kiniksa Pharmaceuticals International's current Cyclically Adjusted PB Ratio of 14.06 is 658% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Kiniksa Pharmaceuticals International and its competitors. For the Drug Manufacturers industry, the median Cyclically Adjusted PB Ratio is 1.86 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Kiniksa Pharmaceuticals International's current Cyclically Adjusted PB Ratio is 14.06, which is 43% above median its own 10-year median of 9.84. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Kiniksa Pharmaceuticals International stock overvalued right now?
Based on GuruFocus' analysis, Kiniksa Pharmaceuticals International (KNSA) is currently considered Modestly Overvalued. The stock's GF Value™ is $48.87, compared to a current price of $63.53 — trading 30% above its estimated fair value. The current Cyclically Adjusted PB Ratio is 14.06, which is 43% above median its 10-year median of 9.84 and 658% above the Drug Manufacturers industry median of 1.86. Kiniksa Pharmaceuticals International's overall GF Score™ is 50/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Kiniksa Pharmaceuticals International (KNSA), the current Cyclically Adjusted PB Ratio is 14.06 as of Jul. 22, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Kiniksa Pharmaceuticals International (KNSA) Overvalued in 2026?
Based on GuruFocus' analysis, Kiniksa Pharmaceuticals International stock appears to be overvalued.
The current stock price of $63.53 is trading 30% above its estimated GF Value™ of $48.87.
GuruFocus considers Kiniksa Pharmaceuticals International to be Modestly Overvalued.
Key valuation signals for KNSA:
Cyclically Adjusted PB Ratio: 14.06 (43% above median its 10-year median of 9.84)
GF Value™: $48.87 vs. price of $63.53 (30% above fair value)
Industry Position: 658% above the Drug Manufacturers median (#715 of 758)
No single metric tells the full story. See the KNSA stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Kiniksa Pharmaceuticals International Business Description
Kiniksa Pharmaceuticals International PLC is a clinical-stage biopharmaceutical company focused on discovering, acquiring, developing, and commercializing therapeutic medicines for patients suffering from debilitating cardiovascular diseases. The company's clinical-stage product candidates include Rilonacept, abiprubart, and Vixarelimab. Geographically, the company earns maximum revenue from United States.
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