Fusion Antibodies (LSE:FAB) Cyclically Adjusted PB Ratio: 0.67 (As of Jul. 28, 2026) — 37% Above Median

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

LSE:FAB Fusion Antibodies PLC LSE:FAB
32 GF Score
Price £0.11
GF Value £0.04
Valuation Significantly Overvalued
! 4 Warning Signs
View Full Analysis

What is Fusion Antibodies Cyclically Adjusted PB Ratio?

Fusion Antibodies LSE:FAB 32 Cyclically Adjusted PB Ratio is 0.67 as of Jul. 28, 2026, which is 37% above its 10-year median of 0.49. GuruFocus rates LSE:FAB with a GF Score™ of 32/100 and a GF Value™ of £0.04 (Significantly Overvalued). The stock has 4 warning signs investors should review. Among 698 Biotechnology companies, Fusion Antibodies ranks better than 69.34% on this metric.

As of today (2026-07-28), Fusion Antibodies's current share price is £0.1075. Fusion Antibodies's Cyclically Adjusted Book per Share for the fiscal year that ended in Mar25 was £0.16. Fusion Antibodies's Cyclically Adjusted PB Ratio for today is 0.67.

The historical rank and industry rank for Fusion Antibodies's Cyclically Adjusted PB Ratio or its related term are showing as below:

LSE:FAB' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.18   Med: 0.49   Max: 1.2
Current: 0.66

During the past 11 years, Fusion Antibodies's highest Cyclically Adjusted PB Ratio was 1.20. The lowest was 0.18. And the median was 0.49.

LSE:FAB's Cyclically Adjusted PB Ratio is ranked better than
69.34% of 698 companies
in the Biotechnology industry
Industry Median: 1.62 vs LSE:FAB: 0.66

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Fusion Antibodies's adjusted book value per share data of for the fiscal year that ended in Mar25 was £0.006. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is £0.16 for the trailing ten years ended in Mar25.

Shiller PE for Stocks: The True Measure of Stock Valuation


Fusion Antibodies  (LSE:FAB) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Fusion Antibodies Cyclically Adjusted PB Ratio Related Terms


Fusion Antibodies Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Fusion Antibodies's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Fusion Antibodies Cyclically Adjusted PB Ratio Chart

Fusion Antibodies Annual Data
Trend Mar16 Mar17 Mar18 Mar19 Mar20 Mar21 Mar22 Mar23 Mar24 Mar25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 0.24 0.38

Fusion Antibodies Semi-Annual Data
Mar15 Mar16 Mar17 Sep17 Mar18 Sep18 Mar19 Sep19 Mar20 Sep20 Mar21 Sep21 Mar22 Sep22 Mar23 Sep23 Mar24 Sep24 Mar25 Sep25
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.24 0.00 0.38 0.00

LSE:FAB vs VRTX, REGN, RVMD: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Fusion Antibodies's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Fusion Antibodies Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Fusion Antibodies's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Fusion Antibodies's Cyclically Adjusted PB Ratio falls into.


LSE:FAB
32GF Score
Fusion Antibodies PLC LSE:FAB
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Fusion Antibodies Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Fusion Antibodies's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=0.1075/0.16
=0.67

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Fusion Antibodies's Cyclically Adjusted Book per Share for the fiscal year that ended in Mar25 is calculated as:

For example, Fusion Antibodies's adjusted Book Value per Share data for the fiscal year that ended in Mar25 was:

Adj_Book=Book Value per Share/CPI of Mar25 (Change)*Current CPI (Mar25)
=0.006/136.1000*136.1000
=0.006

Current CPI (Mar25) = 136.1000.

Fusion Antibodies Annual Data

Book Value per Share CPI Adj_Book
201603 0.066 100.400 0.089
201703 0.077 102.700 0.102
201803 0.298 105.100 0.386
201903 0.242 107.000 0.308
202003 0.218 108.600 0.273
202103 0.185 109.700 0.230
202203 0.142 116.500 0.166
202303 0.043 126.800 0.046
202403 0.019 131.600 0.020
202503 0.006 136.100 0.006

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 0.67 mean?
Fusion Antibodies (LSE:FAB) has a Cyclically Adjusted PB Ratio of 0.67 as of Jul. 28, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Fusion Antibodies and its competitors. This is 37% above median its historical median of 0.49. Over the past decade, Fusion Antibodies' Cyclically Adjusted PB Ratio has ranged from 0.18 to 1.20. According to the industry distribution chart, Fusion Antibodies ranks #214 out of 698 companies in the Biotechnology industry, placing it in the top 30.7%.
Is Fusion Antibodies' Cyclically Adjusted PB Ratio too high?
Fusion Antibodies' current Cyclically Adjusted PB Ratio of 0.67 is 37% above median its 10-year median of 0.49. Over the past 10 years, this metric has ranged from a low of 0.18 to a high of 1.20. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.62. Fusion Antibodies' value of 0.67 is 58.6% below this industry median. Based on the distribution chart, Fusion Antibodies ranks #214 out of 698 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Fusion Antibodies has a GF Score™ of 32/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Fusion Antibodies' Cyclically Adjusted PB Ratio compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Fusion Antibodies ranks #214 out of 698 companies for Cyclically Adjusted PB Ratio. This puts Fusion Antibodies in the upper half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.62. Fusion Antibodies' value of 0.67 is 58.6% below this benchmark. Historically, Fusion Antibodies' own Cyclically Adjusted PB Ratio has ranged from 0.18 to 1.20 over the past decade. While the company's 10-year median is 0.49 vs. the industry median of 1.62, Fusion Antibodies has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.62, based on 698 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Fusion Antibodies's current Cyclically Adjusted PB Ratio of 0.67 is 58.6% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Fusion Antibodies and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.62 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Fusion Antibodies's current Cyclically Adjusted PB Ratio is 0.67, which is 37% above median its own 10-year median of 0.49. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Fusion Antibodies stock overvalued right now?
Based on GuruFocus' analysis, Fusion Antibodies (LSE:FAB) is currently considered Significantly Overvalued. The stock's GF Value™ is £0.04, compared to a current price of £0.11 — trading 168.8% above its estimated fair value. The current Cyclically Adjusted PB Ratio is 0.67, which is 37% above median its 10-year median of 0.49 and 58.6% below the Biotechnology industry median of 1.62. Fusion Antibodies' overall GF Score™ is 32/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Fusion Antibodies (LSE:FAB), the current Cyclically Adjusted PB Ratio is 0.67 as of Jul. 28, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Fusion Antibodies (LSE:FAB) Overvalued in 2026?

Based on GuruFocus' analysis, Fusion Antibodies stock appears to be overvalued. The current stock price of £0.11 is trading 168.8% above its estimated GF Value™ of £0.04. GuruFocus considers Fusion Antibodies to be Significantly Overvalued.

Key valuation signals for LSE:FAB:

  • Cyclically Adjusted PB Ratio: 0.67 (37% above median its 10-year median of 0.49)
  • GF Value™: £0.04 vs. price of £0.11 (168.8% above fair value)
  • GF Score™: 32/100 with 4 warning signs
  • Industry Position: 58.6% below the Biotechnology median (#214 of 698)

No single metric tells the full story. See the LSE:FAB stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Fusion Antibodies Business Description

Address 1 Springbank Road, Springbank Industrial Estate, Dunmurry, Northern Ireland, Belfast, GBR, BT17 0QL
Fusion Antibodies PLC is a Contract Research Organisation (CRO) providing antibody identification, engineering, and expression services for the discovery and development of antibodies for human and veterinary therapeutics, as well as for diagnostics. Its customers are pharmaceutical, biotech, veterinary, diagnostic, and life science research companies. The company's three core service areas include: Discovery (identification, screening, and sequencing of novel antibodies); Engineering (optimising the performance of antibodies); and Supply (production and purification of antibodies for further development). Geographically company generates the majority of its revenue from North America and the Rest of the World, followed by the United Kingdom and the Rest of Europe.
32GF Score

Get the complete analysis for LSE:FAB

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

£0.11
Price
£0.04
GF Value