Biofrontera AG (LTS:0DOL) Cyclically Adjusted PB Ratio: 0.41 (As of Jul. 25, 2026) — 77% Below Median

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LTS:0DOL Biofrontera AG LTS:0DOL
62 GF Score
Price €2.56
GF Value €2.40
Valuation Fairly Valued
! 4 Warning Signs
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What is Biofrontera AG Cyclically Adjusted PB Ratio?

Biofrontera AG LTS:0DOL +1.59% 62 Cyclically Adjusted PB Ratio is 0.41 as of Jul. 25, 2026, which is 77% below its 10-year median of 1.75. GuruFocus rates LTS:0DOL with a GF Score™ of 62/100 and a GF Value™ of €2.40 (Fairly Valued). The stock has 4 warning signs investors should review. Among 756 Drug Manufacturers companies, Biofrontera AG ranks better than 88.76% on this metric.

As of today (2026-07-25), Biofrontera AG's current share price is €2.56. Biofrontera AG's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was €6.24. Biofrontera AG's Cyclically Adjusted PB Ratio for today is 0.41.

The historical rank and industry rank for Biofrontera AG's Cyclically Adjusted PB Ratio or its related term are showing as below:

LTS:0DOL' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.38   Med: 1.75   Max: 259.34
Current: 0.41

During the past years, Biofrontera AG's highest Cyclically Adjusted PB Ratio was 259.34. The lowest was 0.38. And the median was 1.75.

LTS:0DOL's Cyclically Adjusted PB Ratio is ranked better than
88.76% of 756 companies
in the Drug Manufacturers industry
Industry Median: 1.84 vs LTS:0DOL: 0.41

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Biofrontera AG's adjusted book value per share data for the three months ended in Mar. 2026 was €2.813. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is €6.24 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Biofrontera AG  (LTS:0DOL) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Biofrontera AG Cyclically Adjusted PB Ratio Related Terms


Biofrontera AG Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Biofrontera AG's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Biofrontera AG Cyclically Adjusted PB Ratio Chart

Biofrontera AG Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 13.88 7.13 1.65 0.41 0.41

Biofrontera AG Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.44 0.41 0.46 0.41 0.42

LTS:0DOL vs ZTS, UTHR, VTRS: Cyclically Adjusted PB Ratio Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Biofrontera AG's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Biofrontera AG Cyclically Adjusted PB Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Biofrontera AG's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Biofrontera AG's Cyclically Adjusted PB Ratio falls into.


LTS:0DOL
62GF Score
Biofrontera AG LTS:0DOL
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Biofrontera AG Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Biofrontera AG's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=2.56/6.24
=0.41

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Biofrontera AG's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Biofrontera AG's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=2.813/131.2583*131.2583
=2.813

Current CPI (Mar. 2026) = 131.2583.

Biofrontera AG Quarterly Data

Book Value per Share CPI Adj_Book
201606 0.661 100.717 0.861
201609 -1.579 101.017 -2.052
201612 7.823 101.217 10.145
201703 6.132 101.417 7.936
201706 5.038 102.117 6.476
201709 2.350 102.717 3.003
201712 1.640 102.617 2.098
201803 9.616 102.917 12.264
201806 7.607 104.017 9.599
201809 5.689 104.718 7.131
201812 7.167 104.217 9.027
201903 5.909 104.217 7.442
201906 11.012 105.718 13.672
201909 6.215 106.018 7.695
201912 4.341 105.818 5.385
202003 1.859 105.718 2.308
202006 2.066 106.618 2.543
202009 -0.472 105.818 -0.585
202012 3.021 105.518 3.758
202103 9.080 107.518 11.085
202106 7.642 108.486 9.246
202109 5.631 109.435 6.754
202112 20.342 110.384 24.189
202203 10.595 113.968 12.202
202206 7.538 115.760 8.547
202209 5.735 118.818 6.335
202212 6.694 119.345 7.362
202303 5.553 122.402 5.955
202306 5.617 123.140 5.987
202309 4.571 124.195 4.831
202312 6.577 123.773 6.975
202403 5.681 125.038 5.964
202406 2.938 125.882 3.063
202409 2.791 126.198 2.903
202412 3.103 127.041 3.206
202503 3.217 127.779 3.305
202506 2.492 128.412 2.547
202509 2.436 129.255 2.474
202512 2.453 129.361 2.489
202603 2.813 131.258 2.813

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 0.41 mean?
Biofrontera AG (LTS:0DOL) has a Cyclically Adjusted PB Ratio of 0.41 as of Jul. 25, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Biofrontera AG and its competitors. This is 77% below median its historical median of 1.75. Over the past decade, Biofrontera AG's Cyclically Adjusted PB Ratio has ranged from 0.38 to 259.34. According to the industry distribution chart, Biofrontera AG ranks #85 out of 756 companies in the Drug Manufacturers industry, placing it in the top 11.2%.
Is Biofrontera AG's Cyclically Adjusted PB Ratio too high?
Biofrontera AG's current Cyclically Adjusted PB Ratio of 0.41 is 77% below median its 10-year median of 1.75. Over the past 10 years, this metric has ranged from a low of 0.38 to a high of 259.34. The Drug Manufacturers industry median Cyclically Adjusted PB Ratio is 1.84. Biofrontera AG's value of 0.41 is 77.7% below this industry median. Based on the distribution chart, Biofrontera AG ranks #85 out of 756 companies in the Drug Manufacturers industry, which is in the top quartile — a strong position relative to peers. Overall, Biofrontera AG has a GF Score™ of 62/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Biofrontera AG's Cyclically Adjusted PB Ratio compare to ZTS and UTHR?
According to the Drug Manufacturers industry distribution chart, Biofrontera AG ranks #85 out of 756 companies for Cyclically Adjusted PB Ratio. This places Biofrontera AG in the top 11% of its industry — outperforming the majority of peers. The industry median Cyclically Adjusted PB Ratio is 1.84. Biofrontera AG's value of 0.41 is 77.7% below this benchmark. Historically, Biofrontera AG's own Cyclically Adjusted PB Ratio has ranged from 0.38 to 259.34 over the past decade. While the company's 10-year median is 1.75 vs. the industry median of 1.84, Biofrontera AG has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Drug Manufacturers company?
The median Cyclically Adjusted PB Ratio among Drug Manufacturers companies is 1.84, based on 756 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Biofrontera AG's current Cyclically Adjusted PB Ratio of 0.41 is 77.7% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Biofrontera AG and its competitors. For the Drug Manufacturers industry, the median Cyclically Adjusted PB Ratio is 1.84 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Biofrontera AG's current Cyclically Adjusted PB Ratio is 0.41, which is 77% below median its own 10-year median of 1.75. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Biofrontera AG stock overvalued right now?
Based on GuruFocus' analysis, Biofrontera AG (LTS:0DOL) is currently considered Fairly Valued. The stock's GF Value™ is €2.40, compared to a current price of €2.56 — trading 6.7% above its estimated fair value. The current Cyclically Adjusted PB Ratio is 0.41, which is 77% below median its 10-year median of 1.75 and 77.7% below the Drug Manufacturers industry median of 1.84. Biofrontera AG's overall GF Score™ is 62/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Biofrontera AG (LTS:0DOL), the current Cyclically Adjusted PB Ratio is 0.41 as of Jul. 25, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Biofrontera AG (LTS:0DOL) Overvalued in 2026?

Based on GuruFocus' analysis, Biofrontera AG stock appears to be overvalued. The current stock price of €2.56 is trading 6.7% above its estimated GF Value™ of €2.40. GuruFocus considers Biofrontera AG to be Fairly Valued.

Key valuation signals for LTS:0DOL:

  • Cyclically Adjusted PB Ratio: 0.41 (77% below median its 10-year median of 1.75)
  • GF Value™: €2.40 vs. price of €2.56 (6.7% above fair value)
  • GF Score™: 62/100 with 4 warning signs
  • Industry Position: 77.7% below the Drug Manufacturers median (#85 of 756)

No single metric tells the full story. See the LTS:0DOL stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Biofrontera AG Business Description

Other Exchanges B8FK:Germany
Address Hemmelrather Weg 201, Leverkusen, NW, DEU, 51377
Biofrontera AG is active in the field of healthcare. It manufactures pharmaceutical products, especially medical cosmetics and dermatological drugs for the care and treatment of skin diseases. Its suite of products includes the prescription drugs Ameluz and BF-RhodoLED and BF-RhodoLED XL, for the treatment of actinic keratosis and Belixos, for the regenerative care of reddened and inflamed skin. Geographically, the company generates maximum revenue from Germany, and the rest from Spain, the United Kingdom, the rest of Europe, and other regions.
62GF Score

Get the complete analysis for LTS:0DOL

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€2.56
Price
€2.40
GF Value