Nippon Shinyaku Co (MEX:4516N) Cyclically Adjusted PB Ratio: 1.83 (As of Jul. 31, 2026) — 58% Below Median

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

MEX:4516N Nippon Shinyaku Co Ltd MEX:4516N
86 GF Score
Price MXN468.31
GF Value MXN557.50
! 3 Warning Signs
View Full Analysis

What is Nippon Shinyaku Co Cyclically Adjusted PB Ratio?

Nippon Shinyaku Co MEX:4516N 86 Cyclically Adjusted PB Ratio is 1.83 as of Jul. 31, 2026, which is 58% below its 10-year median of 4.36. GuruFocus rates MEX:4516N with a GF Score™ of 86/100 and a GF Value™ of MXN557.50. The stock has 3 warning signs investors should review. Among 746 Drug Manufacturers companies, Nippon Shinyaku Co ranks better than 58.98% on this metric.

As of today (2026-07-31), Nippon Shinyaku Co's current share price is MXN468.31. Nippon Shinyaku Co's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was MXN256.29. Nippon Shinyaku Co's Cyclically Adjusted PB Ratio for today is 1.83.

The historical rank and industry rank for Nippon Shinyaku Co's Cyclically Adjusted PB Ratio or its related term are showing as below:

MEX:4516N' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 1.2   Med: 4.36   Max: 6.39
Current: 1.45

During the past years, Nippon Shinyaku Co's highest Cyclically Adjusted PB Ratio was 6.39. The lowest was 1.20. And the median was 4.36.

MEX:4516N's Cyclically Adjusted PB Ratio is ranked better than
58.98% of 746 companies
in the Drug Manufacturers industry
Industry Median: 1.79 vs MEX:4516N: 1.45

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Nippon Shinyaku Co's adjusted book value per share data for the three months ended in Mar. 2026 was MXN491.562. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is MXN256.29 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Nippon Shinyaku Co  (MEX:4516N) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Nippon Shinyaku Co Cyclically Adjusted PB Ratio Related Terms


Nippon Shinyaku Co Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Nippon Shinyaku Co's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Nippon Shinyaku Co Cyclically Adjusted PB Ratio Chart

Nippon Shinyaku Co Annual Data
Trend Mar17 Mar18 Mar19 Mar20 Mar21 Mar22 Mar23 Mar24 Mar25 Mar26
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 4.52 2.84 1.97 1.50 1.83

Nippon Shinyaku Co Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1.50 1.21 1.26 2.06 1.83

MEX:4516N vs ZTS: Cyclically Adjusted PB Ratio Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Nippon Shinyaku Co's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Nippon Shinyaku Co Cyclically Adjusted PB Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Nippon Shinyaku Co's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Nippon Shinyaku Co's Cyclically Adjusted PB Ratio falls into.


MEX:4516N
86GF Score
Nippon Shinyaku Co Ltd MEX:4516N
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Nippon Shinyaku Co Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Nippon Shinyaku Co's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=468.31/256.29
=1.83

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Nippon Shinyaku Co's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Nippon Shinyaku Co's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=491.562/112.7000*112.7000
=491.562

Current CPI (Mar. 2026) = 112.7000.

Nippon Shinyaku Co Quarterly Data

Book Value per Share CPI Adj_Book
201606 272.138 98.100 312.640
201609 298.201 98.000 342.931
201612 303.348 98.400 347.432
201703 282.446 98.100 324.482
201706 283.476 98.500 324.343
201709 292.996 98.800 334.217
201712 322.258 99.400 365.377
201803 319.078 99.200 362.501
201806 336.875 99.200 382.720
201809 323.677 99.900 365.149
201812 342.870 99.700 387.577
201903 349.651 99.700 395.242
201906 359.042 99.800 405.451
201909 380.553 100.100 428.455
201912 363.269 100.500 407.367
202003 473.986 100.300 532.584
202006 476.205 99.900 537.220
202009 473.212 99.900 533.844
202012 443.803 99.300 503.692
202103 455.547 99.900 513.915
202106 456.769 99.500 517.365
202109 483.849 100.100 544.753
202112 473.431 100.100 533.024
202203 450.208 101.100 501.864
202206 412.318 101.800 456.466
202209 398.514 103.100 435.621
202212 419.789 104.100 454.469
202303 391.674 104.400 422.813
202306 364.614 105.200 390.608
202309 369.910 106.200 392.550
202312 376.339 106.800 397.129
202403 362.203 107.200 380.786
202406 0.000 108.200 0.000
202409 480.263 108.900 497.021
202412 497.992 110.700 506.989
202503 503.191 111.100 510.438
202506 486.478 111.700 490.833
202509 478.380 112.000 481.370
202512 486.393 113.000 485.102
202603 491.562 112.700 491.562

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 1.83 mean?
Nippon Shinyaku Co (MEX:4516N) has a Cyclically Adjusted PB Ratio of 1.83 as of Jul. 31, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Nippon Shinyaku Co and its competitors. This is 58% below median its historical median of 4.36. Over the past decade, Nippon Shinyaku Co's Cyclically Adjusted PB Ratio has ranged from 1.20 to 6.39. According to the industry distribution chart, Nippon Shinyaku Co ranks #306 out of 746 companies in the Drug Manufacturers industry, placing it in the top 41%.
Is Nippon Shinyaku Co's Cyclically Adjusted PB Ratio too high?
Nippon Shinyaku Co's current Cyclically Adjusted PB Ratio of 1.83 is 58% below median its 10-year median of 4.36. Over the past 10 years, this metric has ranged from a low of 1.20 to a high of 6.39. The Drug Manufacturers industry median Cyclically Adjusted PB Ratio is 1.79. Nippon Shinyaku Co's value of 1.83 is 2.2% above this industry median. Based on the distribution chart, Nippon Shinyaku Co ranks #306 out of 746 companies in the Drug Manufacturers industry, which is above the industry midpoint. Overall, Nippon Shinyaku Co has a GF Score™ of 86/100, reflecting its overall financial health beyond just this single metric.
How does Nippon Shinyaku Co's Cyclically Adjusted PB Ratio compare to ZTS?
According to the Drug Manufacturers industry distribution chart, Nippon Shinyaku Co ranks #306 out of 746 companies for Cyclically Adjusted PB Ratio. This puts Nippon Shinyaku Co in the upper half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.79. Nippon Shinyaku Co's value of 1.83 is 2.2% above this benchmark. Historically, Nippon Shinyaku Co's own Cyclically Adjusted PB Ratio has ranged from 1.20 to 6.39 over the past decade. While the company's 10-year median is 4.36 vs. the industry median of 1.79, Nippon Shinyaku Co has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Drug Manufacturers company?
The median Cyclically Adjusted PB Ratio among Drug Manufacturers companies is 1.79, based on 746 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Nippon Shinyaku Co's current Cyclically Adjusted PB Ratio of 1.83 is 2.2% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Nippon Shinyaku Co and its competitors. For the Drug Manufacturers industry, the median Cyclically Adjusted PB Ratio is 1.79 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Nippon Shinyaku Co's current Cyclically Adjusted PB Ratio is 1.83, which is 58% below median its own 10-year median of 4.36. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Nippon Shinyaku Co stock overvalued right now?
Nippon Shinyaku Co (MEX:4516N) has a current Cyclically Adjusted PB Ratio of 1.83. The stock's GF Value™ is MXN557.50, compared to a current price of MXN468.31 — trading 16% below its estimated fair value. The current Cyclically Adjusted PB Ratio is 1.83, which is 58% below median its 10-year median of 4.36 and 2.2% above the Drug Manufacturers industry median of 1.79. Nippon Shinyaku Co's overall GF Score™ is 86/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Nippon Shinyaku Co (MEX:4516N), the current Cyclically Adjusted PB Ratio is 1.83 as of Jul. 31, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Nippon Shinyaku Co (MEX:4516N) Overvalued in 2026?

Based on GuruFocus' analysis, Nippon Shinyaku Co stock appears to be undervalued. The current stock price of MXN468.31 is trading 16% below its estimated GF Value™ of MXN557.50.

Key valuation signals for MEX:4516N:

  • Cyclically Adjusted PB Ratio: 1.83 (58% below median its 10-year median of 4.36)
  • GF Value™: MXN557.50 vs. price of MXN468.31 (16% below fair value)
  • GF Score™: 86/100 with 3 warning signs
  • Industry Position: 2.2% above the Drug Manufacturers median (#306 of 746)

No single metric tells the full story. See the MEX:4516N stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Nippon Shinyaku Co Business Description

Other Exchanges NPPNY:USA4516:Japan
Address 14, Kisshoin Nishinosho Monguchicho, Minami-ku, Kyoto, JPN, 601-8550
Nippon Shinyaku Co Ltd is engaged in the pharmaceuticals and functional food businesses. The Pharmaceuticals Business develops and sells treatments for urological disorders, blood cancer, rare and intractable diseases, and gynecological conditions. The Functional Food Business produces and sells health food ingredients, quality-stabilizing preservatives, protein preparations, and supplements. It generates the majority of its revenue from the Pharmaceuticals segment.
86GF Score

Get the complete analysis for MEX:4516N

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN468.31
Price
MXN557.50
GF Value