Eisai Co (MEX:4523N) Cyclically Adjusted PB Ratio: 1.77 (As of Aug. 09, 2026) — 49% Below Median

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

MEX:4523N Eisai Co Ltd MEX:4523N
77 GF Score
Price MXN888.98
GF Value MXN1,078.35
! 8 Warning Signs
View Full Analysis

What is Eisai Co Cyclically Adjusted PB Ratio?

Eisai Co MEX:4523N 77 Cyclically Adjusted PB Ratio is 1.77 as of Aug. 09, 2026, which is 49% below its 10-year median of 3.50. GuruFocus rates MEX:4523N with a GF Score™ of 77/100 and a GF Value™ of MXN1,078.35. The stock has 8 warning signs investors should review. Among 733 Drug Manufacturers companies, Eisai Co ranks better than 51.84% on this metric.

As of today (2026-08-09), Eisai Co's current share price is MXN888.98. Eisai Co's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was MXN501.92. Eisai Co's Cyclically Adjusted PB Ratio for today is 1.77.

The historical rank and industry rank for Eisai Co's Cyclically Adjusted PB Ratio or its related term are showing as below:

MEX:4523N' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 1.34   Med: 3.5   Max: 6.28
Current: 1.74

During the past years, Eisai Co's highest Cyclically Adjusted PB Ratio was 6.28. The lowest was 1.34. And the median was 3.50.

MEX:4523N's Cyclically Adjusted PB Ratio is ranked better than
51.84% of 733 companies
in the Drug Manufacturers industry
Industry Median: 1.81 vs MEX:4523N: 1.74

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Eisai Co's adjusted book value per share data for the three months ended in Mar. 2026 was MXN362.415. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is MXN501.92 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Eisai Co  (MEX:4523N) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Eisai Co Cyclically Adjusted PB Ratio Related Terms


Eisai Co Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Eisai Co's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Eisai Co Cyclically Adjusted PB Ratio Chart

Eisai Co Annual Data
Trend Mar17 Mar18 Mar19 Mar20 Mar21 Mar22 Mar23 Mar24 Mar25 Mar26
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 2.68 3.26 2.52 1.57 1.77

Eisai Co Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1.57 1.55 1.85 1.70 1.77

MEX:4523N vs ZTS: Cyclically Adjusted PB Ratio Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Eisai Co's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Eisai Co Cyclically Adjusted PB Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Eisai Co's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Eisai Co's Cyclically Adjusted PB Ratio falls into.


MEX:4523N
77GF Score
Eisai Co Ltd MEX:4523N
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Eisai Co Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Eisai Co's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=888.98/501.92
=1.77

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Eisai Co's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Eisai Co's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=362.415/112.7000*112.7000
=362.415

Current CPI (Mar. 2026) = 112.7000.

Eisai Co Quarterly Data

Book Value per Share CPI Adj_Book
201606 335.154 98.100 385.034
201609 363.860 98.000 418.439
201612 368.912 98.400 422.524
201703 340.764 98.100 391.479
201706 328.292 98.500 375.619
201709 339.374 98.800 387.120
201712 358.892 99.400 406.913
201803 355.225 99.200 403.567
201806 371.158 99.200 421.668
201809 366.717 99.900 413.704
201812 366.616 99.700 414.419
201903 382.675 99.700 432.572
201906 377.149 99.800 425.899
201909 390.688 100.100 439.866
201912 388.960 100.500 436.177
202003 515.336 100.300 579.047
202006 508.104 99.900 573.206
202009 495.124 99.900 558.563
202012 449.513 99.300 510.172
202103 460.246 99.900 519.216
202106 455.681 99.500 516.133
202109 475.537 100.100 535.395
202112 461.922 100.100 520.066
202203 438.566 101.100 488.886
202206 421.425 101.800 466.548
202209 405.495 103.100 443.252
202212 390.133 104.100 422.363
202303 376.147 104.400 406.051
202306 357.280 105.200 382.751
202309 353.985 106.200 375.651
202312 336.607 106.800 355.202
202403 338.197 107.200 355.549
202406 364.090 108.200 379.232
202409 400.469 108.900 414.443
202412 420.089 110.700 427.679
202503 409.683 111.100 415.583
202506 383.030 111.700 386.459
202509 376.042 112.000 378.392
202512 364.463 113.000 363.495
202603 362.415 112.700 362.415

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 1.77 mean?
Eisai Co (MEX:4523N) has a Cyclically Adjusted PB Ratio of 1.77 as of Aug. 09, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Eisai Co and its competitors. This is 49% below median its historical median of 3.50. Over the past decade, Eisai Co's Cyclically Adjusted PB Ratio has ranged from 1.34 to 6.28. According to the industry distribution chart, Eisai Co ranks #353 out of 733 companies in the Drug Manufacturers industry, placing it in the top 48.2%.
Is Eisai Co's Cyclically Adjusted PB Ratio too high?
Eisai Co's current Cyclically Adjusted PB Ratio of 1.77 is 49% below median its 10-year median of 3.50. Over the past 10 years, this metric has ranged from a low of 1.34 to a high of 6.28. The Drug Manufacturers industry median Cyclically Adjusted PB Ratio is 1.81. Eisai Co's value of 1.77 is 2.2% below this industry median. Based on the distribution chart, Eisai Co ranks #353 out of 733 companies in the Drug Manufacturers industry, which is above the industry midpoint. Overall, Eisai Co has a GF Score™ of 77/100, reflecting its overall financial health beyond just this single metric.
How does Eisai Co's Cyclically Adjusted PB Ratio compare to ZTS?
According to the Drug Manufacturers industry distribution chart, Eisai Co ranks #353 out of 733 companies for Cyclically Adjusted PB Ratio. This puts Eisai Co in the upper half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.81. Eisai Co's value of 1.77 is 2.2% below this benchmark. Historically, Eisai Co's own Cyclically Adjusted PB Ratio has ranged from 1.34 to 6.28 over the past decade. While the company's 10-year median is 3.50 vs. the industry median of 1.81, Eisai Co has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Drug Manufacturers company?
The median Cyclically Adjusted PB Ratio among Drug Manufacturers companies is 1.81, based on 733 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Eisai Co's current Cyclically Adjusted PB Ratio of 1.77 is 2.2% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Eisai Co and its competitors. For the Drug Manufacturers industry, the median Cyclically Adjusted PB Ratio is 1.81 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Eisai Co's current Cyclically Adjusted PB Ratio is 1.77, which is 49% below median its own 10-year median of 3.50. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Eisai Co stock overvalued right now?
Eisai Co (MEX:4523N) has a current Cyclically Adjusted PB Ratio of 1.77. The stock's GF Value™ is MXN1,078.35, compared to a current price of MXN888.98 — trading 17.6% below its estimated fair value. The current Cyclically Adjusted PB Ratio is 1.77, which is 49% below median its 10-year median of 3.50 and 2.2% below the Drug Manufacturers industry median of 1.81. Eisai Co's overall GF Score™ is 77/100 with 8 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Eisai Co (MEX:4523N), the current Cyclically Adjusted PB Ratio is 1.77 as of Aug. 09, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Eisai Co (MEX:4523N) Overvalued in 2026?

Based on GuruFocus' analysis, Eisai Co stock appears to be undervalued. The current stock price of MXN888.98 is trading 17.6% below its estimated GF Value™ of MXN1,078.35.

Key valuation signals for MEX:4523N:

  • Cyclically Adjusted PB Ratio: 1.77 (49% below median its 10-year median of 3.50)
  • GF Value™: MXN1,078.35 vs. price of MXN888.98 (17.6% below fair value)
  • GF Score™: 77/100 with 8 warning signs
  • Industry Position: 2.2% below the Drug Manufacturers median (#353 of 733)

No single metric tells the full story. See the MEX:4523N stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Eisai Co Business Description

Address 4-6-10 Koishikawa, Bunkyo-ku, Tokyo, JPN, 112-8088
Eisai Co Ltd is a specialty and generic drug manufacturing company. The company's business consists of research and development, manufacturing, sales, import, and export of pharmaceuticals. The pharmaceutical business is categorized by region, including East Asia & Global South; Europe, Middle East, Africa, Russia, Oceania (EMEA); Americas; China; and Japan. The company also reports a consumer healthcare business for Japan. The vast majority of the company's revenue is derived from its American pharmaceutical business, followed by its Japanese pharmaceuticals segment. The company utilizes licensing strategies in order to expand its research, development, manufacturing, and marketing capabilities.
77GF Score

Get the complete analysis for MEX:4523N

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN888.98
Price
MXN1,078.35
GF Value