Ardelyx (MEX:ARDX) Cyclically Adjusted PB Ratio: 2.40 (As of Jul. 19, 2026) — 12% Above Median

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Director of Data and Quant Analytics at GuruFocus
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Founder & CEO of GuruFocus
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MEX:ARDX Ardelyx Inc MEX:ARDX
69 GF Score
Price MXN99.00
GF Value MXN217.64
Valuation Possible Value Trap
! 6 Warning Signs
View Full Analysis

What is Ardelyx Cyclically Adjusted PB Ratio?

Ardelyx MEX:ARDX 69 Cyclically Adjusted PB Ratio is 2.40 as of Jul. 19, 2026, which is 12% above its 10-year median of 2.14. GuruFocus rates MEX:ARDX with a GF Score™ of 69/100 and a GF Value™ of MXN217.64 (Possible Value Trap). The stock has 6 warning signs investors should review. Among 698 Biotechnology companies, Ardelyx ranks worse than 62.89% on this metric.

As of today (2026-07-19), Ardelyx's current share price is MXN99.00. Ardelyx's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was MXN41.28. Ardelyx's Cyclically Adjusted PB Ratio for today is 2.40.

The historical rank and industry rank for Ardelyx's Cyclically Adjusted PB Ratio or its related term are showing as below:

MEX:ARDX' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.47   Med: 2.14   Max: 3.81
Current: 2.7

During the past years, Ardelyx's highest Cyclically Adjusted PB Ratio was 3.81. The lowest was 0.47. And the median was 2.14.

MEX:ARDX's Cyclically Adjusted PB Ratio is ranked worse than
62.89% of 698 companies
in the Biotechnology industry
Industry Median: 1.605 vs MEX:ARDX: 2.70

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Ardelyx's adjusted book value per share data for the three months ended in Mar. 2026 was MXN10.852. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is MXN41.28 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Ardelyx  (MEX:ARDX) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Ardelyx Cyclically Adjusted PB Ratio Related Terms


Ardelyx Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Ardelyx's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ardelyx Cyclically Adjusted PB Ratio Chart

Ardelyx Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 1.08 2.30 2.02 2.86

Ardelyx Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 2.00 1.70 2.54 2.86 3.11

MEX:ARDX vs AVLN, INBX, JBIO: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Ardelyx's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Ardelyx Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Ardelyx's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Ardelyx's Cyclically Adjusted PB Ratio falls into.


MEX:ARDX
69GF Score
Ardelyx Inc MEX:ARDX
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Ardelyx Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Ardelyx's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=99.00/41.28
=2.40

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ardelyx's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Ardelyx's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=10.852/330.2130*330.2130
=10.852

Current CPI (Mar. 2026) = 330.2130.

Ardelyx Quarterly Data

Book Value per Share CPI Adj_Book
201606 75.044 241.018 102.816
201609 91.123 241.428 124.633
201612 84.174 241.432 115.127
201703 66.628 243.801 90.243
201706 55.237 244.955 74.463
201709 48.379 246.819 64.725
201712 57.558 246.524 77.098
201803 49.222 249.554 65.131
201806 51.745 251.989 67.808
201809 42.601 252.439 55.726
201812 36.374 251.233 47.809
201903 28.459 254.202 36.969
201906 20.988 256.143 27.057
201909 15.433 256.759 19.848
201912 39.635 256.974 50.931
202003 44.180 258.115 56.521
202006 37.896 257.797 48.541
202009 32.151 260.280 40.789
202012 26.801 260.474 33.977
202103 27.094 264.877 33.777
202106 22.729 271.696 27.624
202109 15.682 274.310 18.878
202112 13.019 278.802 15.420
202203 9.375 287.504 10.768
202206 6.938 296.311 7.732
202209 7.177 296.808 7.985
202212 9.654 296.797 10.741
202303 10.541 301.836 11.532
202306 9.692 305.109 10.489
202309 14.344 307.789 15.389
202312 12.181 306.746 13.113
202403 10.704 312.332 11.317
202406 11.440 314.175 12.024
202409 13.158 315.301 13.780
202412 15.184 315.605 15.887
202503 12.459 319.799 12.865
202506 10.912 322.561 11.171
202509 11.648 324.800 11.842
202512 12.302 324.054 12.536
202603 10.852 330.213 10.852

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 2.40 mean?
Ardelyx (MEX:ARDX) has a Cyclically Adjusted PB Ratio of 2.40 as of Jul. 19, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Ardelyx and its competitors. This is 12% above median its historical median of 2.14. Over the past decade, Ardelyx's Cyclically Adjusted PB Ratio has ranged from 0.47 to 3.81. According to the industry distribution chart, Ardelyx ranks #439 out of 698 companies in the Biotechnology industry, placing it in the top 62.9%.
Is Ardelyx's Cyclically Adjusted PB Ratio too high?
Ardelyx's current Cyclically Adjusted PB Ratio of 2.40 is 12% above median its 10-year median of 2.14. Over the past 10 years, this metric has ranged from a low of 0.47 to a high of 3.81. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.61. Ardelyx's value of 2.40 is 49.5% above this industry median. Based on the distribution chart, Ardelyx ranks #439 out of 698 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Ardelyx has a GF Score™ of 69/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Ardelyx's Cyclically Adjusted PB Ratio compare to AVLN and INBX?
According to the Biotechnology industry distribution chart, Ardelyx ranks #439 out of 698 companies for Cyclically Adjusted PB Ratio. This places Ardelyx in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.61. Ardelyx's value of 2.40 is 49.5% above this benchmark. Historically, Ardelyx's own Cyclically Adjusted PB Ratio has ranged from 0.47 to 3.81 over the past decade. While the company's 10-year median is 2.14 vs. the industry median of 1.61, Ardelyx has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.61, based on 698 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Ardelyx's current Cyclically Adjusted PB Ratio of 2.40 is 49.5% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Ardelyx and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.61 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Ardelyx's current Cyclically Adjusted PB Ratio is 2.40, which is 12% above median its own 10-year median of 2.14. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Ardelyx stock overvalued right now?
Based on GuruFocus' analysis, Ardelyx (MEX:ARDX) is currently considered Possible Value Trap. The stock's GF Value™ is MXN217.64, compared to a current price of MXN99.00 — trading 54.5% below its estimated fair value. The current Cyclically Adjusted PB Ratio is 2.40, which is 12% above median its 10-year median of 2.14 and 49.5% above the Biotechnology industry median of 1.61. Ardelyx's overall GF Score™ is 69/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Ardelyx (MEX:ARDX), the current Cyclically Adjusted PB Ratio is 2.40 as of Jul. 19, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Ardelyx (MEX:ARDX) Overvalued in 2026?

Based on GuruFocus' analysis, Ardelyx stock appears to be undervalued. The current stock price of MXN99.00 is trading 54.5% below its estimated GF Value™ of MXN217.64. GuruFocus considers Ardelyx to be Possible Value Trap.

Key valuation signals for MEX:ARDX:

  • Cyclically Adjusted PB Ratio: 2.40 (12% above median its 10-year median of 2.14)
  • GF Value™: MXN217.64 vs. price of MXN99.00 (54.5% below fair value)
  • GF Score™: 69/100 with 6 warning signs
  • Industry Position: 49.5% above the Biotechnology median (#439 of 698)

No single metric tells the full story. See the MEX:ARDX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Ardelyx Business Description

Other Exchanges ARDX:USA41X:Germany
Address 400 Fifth Avenue, Suite 210, Waltham, MA, USA, 02451
Ardelyx Inc is a biopharmaceutical company developing and commercialize, first-in-class medicines that meet unmet medical needs. It has developed a platform that enabled the discovery of new biological mechanisms and pathways to develop potent and efficacious therapies that minimize the side effects and drug-drug interactions frequently encountered with traditional, systemically absorbed medicines. Its products Tenapanor, branded as IBSRELA, is used for the treatment of adults with IBS-C. Tenapanor, branded as XPHOZAH, is used to reduce serum phosphorus in adults with CKD on dialysis as add-on therapy in patients who have an inadequate response to phosphate binders or who are intolerant of any dose of phosphate binder therapy.
69GF Score

Get the complete analysis for MEX:ARDX

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN99.00
Price
MXN217.64
GF Value