AstraZeneca (MEX:AZN1N) Cyclically Adjusted PB Ratio: 7.34 (As of Sep. 14, 2026) — Near Median

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MEX:AZN1N AstraZeneca PLC MEX:AZN1N
84 GF Score
Price MXN2,777.00
GF Value MXN3,041.09
Valuation Fairly Valued
! 1 Warning Sign
View Full Analysis

What is AstraZeneca Cyclically Adjusted PB Ratio?

AstraZeneca MEX:AZN1N 84 Cyclically Adjusted PB Ratio is 7.34 as of Sep. 14, 2026, which is 7% below its 10-year median of 7.89. GuruFocus rates MEX:AZN1N with a GF Score™ of 84/100 and a GF Value™ of MXN3,041.09 (Fairly Valued). The stock has 1 warning sign investors should review. Among 636 Drug Manufacturers companies, AstraZeneca ranks worse than 90.25% on this metric.

As of today (2026-09-14), AstraZeneca's current share price is MXN2777.00. AstraZeneca's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 was MXN378.21. AstraZeneca's Cyclically Adjusted PB Ratio for today is 7.34.

The historical rank and industry rank for AstraZeneca's Cyclically Adjusted PB Ratio or its related term are showing as below:

MEX:AZN1N' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 4.21   Med: 7.89   Max: 10.1
Current: 7.17

During the past years, AstraZeneca's highest Cyclically Adjusted PB Ratio was 10.10. The lowest was 4.21. And the median was 7.89.

MEX:AZN1N's Cyclically Adjusted PB Ratio is ranked worse than
90.25% of 636 companies
in the Drug Manufacturers industry
Industry Median: 1.685 vs MEX:AZN1N: 7.17

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

AstraZeneca's adjusted book value per share data for the three months ended in Jun. 2026 was MXN565.872. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is MXN378.21 for the trailing ten years ended in Jun. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


AstraZeneca  (MEX:AZN1N) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


AstraZeneca Cyclically Adjusted PB Ratio Related Terms


AstraZeneca Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for AstraZeneca's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

AstraZeneca Cyclically Adjusted PB Ratio Chart

AstraZeneca Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 8.24 9.33 8.20 7.46 8.93

AstraZeneca Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 6.84 7.41 8.93 9.28 8.63

MEX:AZN1N vs LLY, JNJ, ABBV: Cyclically Adjusted PB Ratio Comparison

For the Drug Manufacturers - General subindustry, AstraZeneca's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


AstraZeneca Cyclically Adjusted PB Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, AstraZeneca's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where AstraZeneca's Cyclically Adjusted PB Ratio falls into.


MEX:AZN1N
84GF Score
AstraZeneca PLC MEX:AZN1N
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

AstraZeneca Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

AstraZeneca's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=2777.00/378.21
=7.34

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

AstraZeneca's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 is calculated as:

For example, AstraZeneca's adjusted Book Value per Share data for the three months ended in Jun. 2026 was:

Adj_Book=Book Value per Share/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=565.872/142.3000*142.3000
=565.872

Current CPI (Jun. 2026) = 142.3000.

AstraZeneca Quarterly Data

Book Value per Share CPI Adj_Book
201609 199.805 101.500 280.121
201612 242.047 102.200 337.018
201703 193.183 102.700 267.672
201706 194.973 103.500 268.064
201709 196.760 104.300 268.446
201712 232.034 105.000 314.461
201803 185.249 105.100 250.818
201806 196.159 105.900 263.583
201809 176.244 106.600 235.268
201812 193.214 107.100 256.717
201903 155.021 107.000 206.163
201906 198.389 107.900 261.638
201909 183.051 108.400 240.297
201912 188.681 108.500 247.459
202003 192.594 108.600 252.358
202006 215.242 108.800 281.516
202009 205.289 109.200 267.515
202012 236.734 109.400 307.927
202103 224.693 109.700 291.466
202106 237.698 111.400 303.630
202109 527.530 112.400 667.860
202112 519.907 114.700 645.011
202203 466.981 116.500 570.398
202206 466.530 120.500 550.931
202209 456.093 122.300 530.679
202212 465.914 125.300 529.127
202303 416.233 126.800 467.113
202306 413.610 129.400 454.843
202309 418.045 130.100 457.247
202312 428.615 130.500 467.371
202403 400.876 131.600 433.470
202406 466.928 133.000 499.578
202409 517.172 133.500 551.263
202412 548.751 135.100 577.996
202503 541.604 136.100 566.277
202506 543.161 138.400 558.467
202509 542.992 138.900 556.283
202512 565.067 139.900 574.761
202603 550.376 140.800 556.239
202606 565.872 142.300 565.872

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 7.34 mean?
AstraZeneca (MEX:AZN1N) has a Cyclically Adjusted PB Ratio of 7.34 as of Sep. 14, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on AstraZeneca and its competitors. This is near median its historical median of 7.89. Over the past decade, AstraZeneca's Cyclically Adjusted PB Ratio has ranged from 4.21 to 10.10. According to the industry distribution chart, AstraZeneca ranks #574 out of 636 companies in the Drug Manufacturers industry, placing it in the top 90.3%.
Is AstraZeneca's Cyclically Adjusted PB Ratio too high?
AstraZeneca's current Cyclically Adjusted PB Ratio of 7.34 is near median its 10-year median of 7.89. Over the past 10 years, this metric has ranged from a low of 4.21 to a high of 10.10. The Drug Manufacturers industry median Cyclically Adjusted PB Ratio is 1.69. AstraZeneca's value of 7.34 is 335.6% above this industry median. Based on the distribution chart, AstraZeneca ranks #574 out of 636 companies in the Drug Manufacturers industry, which is in the bottom quartile relative to peers. Overall, AstraZeneca has a GF Score™ of 84/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does AstraZeneca's Cyclically Adjusted PB Ratio compare to LLY and JNJ?
According to the Drug Manufacturers industry distribution chart, AstraZeneca ranks #574 out of 636 companies for Cyclically Adjusted PB Ratio. This places AstraZeneca in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.69. AstraZeneca's value of 7.34 is 335.6% above this benchmark. Historically, AstraZeneca's own Cyclically Adjusted PB Ratio has ranged from 4.21 to 10.10 over the past decade. While the company's 10-year median is 7.89 vs. the industry median of 1.69, AstraZeneca has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Drug Manufacturers company?
The median Cyclically Adjusted PB Ratio among Drug Manufacturers companies is 1.69, based on 636 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. AstraZeneca's current Cyclically Adjusted PB Ratio of 7.34 is 335.6% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on AstraZeneca and its competitors. For the Drug Manufacturers industry, the median Cyclically Adjusted PB Ratio is 1.69 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. AstraZeneca's current Cyclically Adjusted PB Ratio is 7.34, which is near median its own 10-year median of 7.89. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is AstraZeneca stock overvalued right now?
Based on GuruFocus' analysis, AstraZeneca (MEX:AZN1N) is currently considered Fairly Valued. The stock's GF Value™ is MXN3,041.09, compared to a current price of MXN2,777.00 — trading 8.7% below its estimated fair value. The current Cyclically Adjusted PB Ratio is 7.34, which is near median its 10-year median of 7.89 and 335.6% above the Drug Manufacturers industry median of 1.69. AstraZeneca's overall GF Score™ is 84/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For AstraZeneca (MEX:AZN1N), the current Cyclically Adjusted PB Ratio is 7.34 as of Sep. 14, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is AstraZeneca (MEX:AZN1N) Overvalued in 2026?

Based on GuruFocus' analysis, AstraZeneca stock appears to be undervalued. The current stock price of MXN2,777.00 is trading 8.7% below its estimated GF Value™ of MXN3,041.09. GuruFocus considers AstraZeneca to be Fairly Valued.

Key valuation signals for MEX:AZN1N:

  • Cyclically Adjusted PB Ratio: 7.34 (near median its 10-year median of 7.89)
  • GF Value™: MXN3,041.09 vs. price of MXN2,777.00 (8.7% below fair value)
  • GF Score™: 84/100 with 1 warning sign
  • Industry Position: 335.6% above the Drug Manufacturers median (#574 of 636)

No single metric tells the full story. See the MEX:AZN1N stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


AstraZeneca Business Description

Address 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, GBR, CB2 0AA
A merger between Astra of Sweden and Zeneca of the United Kingdom formed AstraZeneca in 1999. The firm sells branded drugs across a number of major therapeutic areas, including oncology (over 40% of total revenue), cardiovascular, renal, and metabolic (over 20%), rare disease (16%), and respiratory and immunology (15%). The majority of sales comes from international markets, with the United States representing close to one-third of its sales.
84GF Score

Get the complete analysis for MEX:AZN1N

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN2,777.00
Price
MXN3,041.09
GF Value