Hologic (MEX:HOLX) Cyclically Adjusted PB Ratio: 4.49 (As of Jul. 27, 2026) — Near Median

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MEX:HOLX Hologic Inc MEX:HOLX
57 GF Score
Price MXN1,260.00
GF Value MXN1,360.12
! 5 Warning Signs
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What is Hologic Cyclically Adjusted PB Ratio?

Hologic MEX:HOLX 57 Cyclically Adjusted PB Ratio is 4.49 as of Jul. 27, 2026, which is 9% below its 10-year median of 4.95. GuruFocus rates MEX:HOLX with a GF Score™ of 57/100 and a GF Value™ of MXN1,360.12. The stock has 5 warning signs investors should review.

As of today (2026-07-27), Hologic's current share price is MXN1260.00. Hologic's Cyclically Adjusted Book per Share for the quarter that ended in Dec. 2025 was MXN280.45. Hologic's Cyclically Adjusted PB Ratio for today is 4.49.

The historical rank and industry rank for Hologic's Cyclically Adjusted PB Ratio or its related term are showing as below:

MEX:HOLX' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 3.09   Med: 4.95   Max: 8.37
Current: 4.59

During the past years, Hologic's highest Cyclically Adjusted PB Ratio was 8.37. The lowest was 3.09. And the median was 4.95.

MEX:HOLX's Cyclically Adjusted PB Ratio is not ranked
in the Medical Devices & Instruments industry.
Industry Median: 1.8 vs MEX:HOLX: 4.59

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Hologic's adjusted book value per share data for the three months ended in Dec. 2025 was MXN423.380. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is MXN280.45 for the trailing ten years ended in Dec. 2025.

Shiller PE for Stocks: The True Measure of Stock Valuation


Hologic  (MEX:HOLX) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Hologic Cyclically Adjusted PB Ratio Related Terms


Hologic Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Hologic's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Hologic Cyclically Adjusted PB Ratio Chart

Hologic Annual Data
Trend Sep16 Sep17 Sep18 Sep19 Sep20 Sep21 Sep22 Sep23 Sep24 Sep25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 6.96 5.38 5.25 5.54 4.14

Hologic Quarterly Data
Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 4.81 4.00 4.11 4.14 4.49

MEX:HOLX vs WST, COO, ALGN: Cyclically Adjusted PB Ratio Comparison

For the Medical Instruments & Supplies subindustry, Hologic's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Hologic Cyclically Adjusted PB Ratio vs Medical Devices & Instruments Industry

For the Medical Devices & Instruments industry and Healthcare sector, Hologic's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Hologic's Cyclically Adjusted PB Ratio falls into.


MEX:HOLX
57GF Score
Hologic Inc MEX:HOLX
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Hologic Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Hologic's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=1260.00/280.45
=4.49

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Hologic's Cyclically Adjusted Book per Share for the quarter that ended in Dec. 2025 is calculated as:

For example, Hologic's adjusted Book Value per Share data for the three months ended in Dec. 2025 was:

Adj_Book=Book Value per Share/CPI of Dec. 2025 (Change)*Current CPI (Dec. 2025)
=423.38/324.0540*324.0540
=423.380

Current CPI (Dec. 2025) = 324.0540.

Hologic Quarterly Data

Book Value per Share CPI Adj_Book
201603 125.795 238.132 171.184
201606 136.342 241.018 183.315
201609 149.176 241.428 200.230
201612 164.541 241.432 220.850
201703 188.292 243.801 250.273
201706 184.844 244.955 244.532
201709 183.574 246.819 241.018
201712 227.121 246.524 298.549
201803 162.268 249.554 210.710
201806 177.040 251.989 227.671
201809 168.207 252.439 215.926
201812 161.645 251.233 208.499
201903 156.306 254.202 199.257
201906 159.432 256.143 201.702
201909 156.035 256.759 196.931
201912 160.871 256.974 202.864
202003 189.445 258.115 237.841
202006 201.174 257.797 252.878
202009 232.082 260.280 288.947
202012 252.491 260.474 314.122
202103 302.732 264.877 370.366
202106 304.698 271.696 363.416
202109 341.974 274.310 403.988
202112 368.027 278.802 427.761
202203 382.702 287.504 431.354
202206 403.023 296.311 440.757
202209 396.892 296.808 433.325
202212 402.699 296.797 439.682
202303 388.229 301.836 416.806
202306 362.697 305.109 385.218
202309 361.546 307.789 380.652
202312 336.801 306.746 355.805
202403 344.504 312.332 357.433
202406 390.858 314.175 403.148
202409 435.910 315.301 448.011
202412 441.348 315.605 453.163
202503 424.020 319.799 429.662
202506 410.321 322.561 412.220
202509 416.059 324.800 415.103
202512 423.380 324.054 423.380

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 4.49 mean?
Hologic (MEX:HOLX) has a Cyclically Adjusted PB Ratio of 4.49 as of Jul. 27, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Hologic and its competitors. This is near median its historical median of 4.95. Over the past decade, Hologic's Cyclically Adjusted PB Ratio has ranged from 3.09 to 8.37.
Is Hologic's Cyclically Adjusted PB Ratio too high?
Hologic's current Cyclically Adjusted PB Ratio of 4.49 is near median its 10-year median of 4.95. Over the past 10 years, this metric has ranged from a low of 3.09 to a high of 8.37. The Medical Devices & Instruments industry median Cyclically Adjusted PB Ratio is 1.80. Hologic's value of 4.49 is 149.4% above this industry median. Overall, Hologic has a GF Score™ of 57/100, reflecting its overall financial health beyond just this single metric.
How does Hologic's Cyclically Adjusted PB Ratio compare to WST and COO?
Hologic's Cyclically Adjusted PB Ratio of 4.49 can be compared against companies in the Medical Devices & Instruments industry. The industry median Cyclically Adjusted PB Ratio is 1.80. Hologic's value of 4.49 is 149.4% above this benchmark. Historically, Hologic's own Cyclically Adjusted PB Ratio has ranged from 3.09 to 8.37 over the past decade. While the company's 10-year median is 4.95 vs. the industry median of 1.80, Hologic has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Medical Devices & Instruments company?
The median Cyclically Adjusted PB Ratio among Medical Devices & Instruments companies is 1.80, based on 521 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Hologic's current Cyclically Adjusted PB Ratio of 4.49 is 149.4% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Hologic and its competitors. For the Medical Devices & Instruments industry, the median Cyclically Adjusted PB Ratio is 1.80 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Hologic's current Cyclically Adjusted PB Ratio is 4.49, which is near median its own 10-year median of 4.95. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Hologic stock overvalued right now?
Hologic (MEX:HOLX) has a current Cyclically Adjusted PB Ratio of 4.49. The stock's GF Value™ is MXN1,360.12, compared to a current price of MXN1,260.00 — trading 7.4% below its estimated fair value. The current Cyclically Adjusted PB Ratio is 4.49, which is near median its 10-year median of 4.95 and 149.4% above the Medical Devices & Instruments industry median of 1.80. Hologic's overall GF Score™ is 57/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Hologic (MEX:HOLX), the current Cyclically Adjusted PB Ratio is 4.49 as of Jul. 27, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Hologic (MEX:HOLX) Overvalued in 2026?

Based on GuruFocus' analysis, Hologic stock appears to be undervalued. The current stock price of MXN1,260.00 is trading 7.4% below its estimated GF Value™ of MXN1,360.12.

Key valuation signals for MEX:HOLX:

  • Cyclically Adjusted PB Ratio: 4.49 (near median its 10-year median of 4.95)
  • GF Value™: MXN1,360.12 vs. price of MXN1,260.00 (7.4% below fair value)
  • GF Score™: 57/100 with 5 warning signs
  • Industry Position: 149.4% above the Medical Devices & Instruments median

No single metric tells the full story. See the MEX:HOLX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Hologic Business Description

Address 250 Campus Drive, Marlborough, MA, USA, 01752
Hologic manufactures proprietary products for the healthcare needs of women. The company operates in four segments: diagnostics (44% of total sales), breast health (38%), surgical (16%), and skeletal health (2%). While the company traditionally focused on breast health, the acquisition of Gen-Probe put greater emphasis on commercial diagnostics. The United States accounts for the largest portion of the firm's revenue (69%), followed by Europe (20%), Asia (8%), and other international markets (3%). Hologic is headquartered in Bedford, Massachusetts.
57GF Score

Get the complete analysis for MEX:HOLX

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN1,260.00
Price
MXN1,360.12
GF Value