Voyager Therapeutics (MEX:VYGR) Cyclically Adjusted PB Ratio: 0.81 (As of Aug. 13, 2026) — 12% Below Median

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MEX:VYGR Voyager Therapeutics Inc MEX:VYGR
54 GF Score
Price MXN63.00
GF Value MXN32.88
! 5 Warning Signs
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What is Voyager Therapeutics Cyclically Adjusted PB Ratio?

Voyager Therapeutics MEX:VYGR 54 Cyclically Adjusted PB Ratio is 0.81 as of Aug. 13, 2026, which is 12% below its 10-year median of 0.92. GuruFocus rates MEX:VYGR with a GF Score™ of 54/100 and a GF Value™ of MXN32.88. The stock has 5 warning signs investors should review. Among 694 Biotechnology companies, Voyager Therapeutics ranks better than 67% on this metric.

As of today (2026-08-13), Voyager Therapeutics's current share price is MXN63.00. Voyager Therapeutics's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 was MXN77.58. Voyager Therapeutics's Cyclically Adjusted PB Ratio for today is 0.81.

The historical rank and industry rank for Voyager Therapeutics's Cyclically Adjusted PB Ratio or its related term are showing as below:

MEX:VYGR' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0.62   Med: 0.92   Max: 2.37
Current: 0.74

During the past years, Voyager Therapeutics's highest Cyclically Adjusted PB Ratio was 2.37. The lowest was 0.62. And the median was 0.92.

MEX:VYGR's Cyclically Adjusted PB Ratio is ranked better than
67% of 694 companies
in the Biotechnology industry
Industry Median: 1.63 vs MEX:VYGR: 0.74

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Voyager Therapeutics's adjusted book value per share data for the three months ended in Jun. 2026 was MXN43.963. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is MXN77.58 for the trailing ten years ended in Jun. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Voyager Therapeutics  (MEX:VYGR) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Voyager Therapeutics Cyclically Adjusted PB Ratio Related Terms


Voyager Therapeutics Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Voyager Therapeutics's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Voyager Therapeutics Cyclically Adjusted PB Ratio Chart

Voyager Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 1.30 0.88

Voyager Therapeutics Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.70 1.01 0.88 0.88 0.81

MEX:VYGR vs NERV, DTIL, GLSI: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Voyager Therapeutics's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Voyager Therapeutics Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Voyager Therapeutics's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Voyager Therapeutics's Cyclically Adjusted PB Ratio falls into.


MEX:VYGR
54GF Score
Voyager Therapeutics Inc MEX:VYGR
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Voyager Therapeutics Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Voyager Therapeutics's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=63.00/77.58
=0.81

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Voyager Therapeutics's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 is calculated as:

For example, Voyager Therapeutics's adjusted Book Value per Share data for the three months ended in Jun. 2026 was:

Adj_Book=Book Value per Share/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=43.963/333.9520*333.9520
=43.963

Current CPI (Jun. 2026) = 333.9520.

Voyager Therapeutics Quarterly Data

Book Value per Share CPI Adj_Book
201609 113.434 241.428 156.906
201612 109.474 241.432 151.426
201703 89.365 243.801 122.410
201706 73.193 244.955 99.785
201709 58.907 246.819 79.703
201712 83.387 246.524 112.960
201803 55.999 249.554 74.938
201806 50.234 251.989 66.573
201809 37.970 252.439 50.231
201812 28.178 251.233 37.456
201903 53.403 254.202 70.157
201906 62.010 256.143 80.847
201909 57.978 256.759 75.409
201912 50.910 256.974 66.160
202003 50.576 258.115 65.436
202006 47.700 257.797 61.791
202009 98.551 260.280 126.446
202012 82.149 260.474 105.323
202103 74.135 264.877 93.468
202106 58.253 271.696 71.601
202109 47.577 274.310 57.921
202112 51.426 278.802 61.599
202203 39.534 287.504 45.921
202206 31.430 296.311 35.423
202209 41.683 296.808 46.899
202212 29.799 296.797 33.529
202303 90.034 301.836 99.614
202306 77.974 305.109 85.345
202309 69.907 307.789 75.849
202312 91.088 306.746 99.167
202403 104.154 312.332 111.364
202406 112.808 314.175 119.909
202409 119.246 315.301 126.300
202412 114.226 315.605 120.866
202503 101.052 319.799 105.524
202506 82.915 322.561 85.843
202509 72.661 324.800 74.708
202512 59.792 324.054 61.618
202603 51.926 330.213 52.514
202606 43.963 333.952 43.963

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 0.81 mean?
Voyager Therapeutics (MEX:VYGR) has a Cyclically Adjusted PB Ratio of 0.81 as of Aug. 13, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Voyager Therapeutics and its competitors. This is 12% below median its historical median of 0.92. Over the past decade, Voyager Therapeutics' Cyclically Adjusted PB Ratio has ranged from 0.62 to 2.37. According to the industry distribution chart, Voyager Therapeutics ranks #229 out of 694 companies in the Biotechnology industry, placing it in the top 33%.
Is Voyager Therapeutics' Cyclically Adjusted PB Ratio too high?
Voyager Therapeutics' current Cyclically Adjusted PB Ratio of 0.81 is 12% below median its 10-year median of 0.92. Over the past 10 years, this metric has ranged from a low of 0.62 to a high of 2.37. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.63. Voyager Therapeutics' value of 0.81 is 50.3% below this industry median. Based on the distribution chart, Voyager Therapeutics ranks #229 out of 694 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Voyager Therapeutics has a GF Score™ of 54/100, reflecting its overall financial health beyond just this single metric.
How does Voyager Therapeutics' Cyclically Adjusted PB Ratio compare to NERV and DTIL?
According to the Biotechnology industry distribution chart, Voyager Therapeutics ranks #229 out of 694 companies for Cyclically Adjusted PB Ratio. This puts Voyager Therapeutics in the upper half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.63. Voyager Therapeutics' value of 0.81 is 50.3% below this benchmark. Historically, Voyager Therapeutics' own Cyclically Adjusted PB Ratio has ranged from 0.62 to 2.37 over the past decade. While the company's 10-year median is 0.92 vs. the industry median of 1.63, Voyager Therapeutics has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.63, based on 694 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Voyager Therapeutics's current Cyclically Adjusted PB Ratio of 0.81 is 50.3% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Voyager Therapeutics and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.63 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Voyager Therapeutics's current Cyclically Adjusted PB Ratio is 0.81, which is 12% below median its own 10-year median of 0.92. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Voyager Therapeutics stock overvalued right now?
Voyager Therapeutics (MEX:VYGR) has a current Cyclically Adjusted PB Ratio of 0.81. The stock's GF Value™ is MXN32.88, compared to a current price of MXN63.00 — trading 91.6% above its estimated fair value. The current Cyclically Adjusted PB Ratio is 0.81, which is 12% below median its 10-year median of 0.92 and 50.3% below the Biotechnology industry median of 1.63. Voyager Therapeutics' overall GF Score™ is 54/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Voyager Therapeutics (MEX:VYGR), the current Cyclically Adjusted PB Ratio is 0.81 as of Aug. 13, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Voyager Therapeutics (MEX:VYGR) Overvalued in 2026?

Based on GuruFocus' analysis, Voyager Therapeutics stock appears to be overvalued. The current stock price of MXN63.00 is trading 91.6% above its estimated GF Value™ of MXN32.88.

Key valuation signals for MEX:VYGR:

  • Cyclically Adjusted PB Ratio: 0.81 (12% below median its 10-year median of 0.92)
  • GF Value™: MXN32.88 vs. price of MXN63.00 (91.6% above fair value)
  • GF Score™: 54/100 with 5 warning signs
  • Industry Position: 50.3% below the Biotechnology median (#229 of 694)

No single metric tells the full story. See the MEX:VYGR stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Voyager Therapeutics Business Description

Other Exchanges VYGR:USAVT6:Germany
Address 75 Hayden Avenue, Lexington, MA, USA, 02421
Voyager Therapeutics Inc is a biotechnology company to leverage the power of human genetics to modify the course of and ultimately cure neurological diseases. Its pipeline includes programs for Alzheimer's disease, or AD; Friedreich's ataxia, or FA; Parkinson's disease, or PD; and multiple other diseases of the central nervous system, or CNS. Many of its programs are derived from its TRACER (Tropism Redirection of AAV by Cell-type-specific Expression of RNA) adeno-associated virus, or AAV, capsid discovery platform, which the company has used to generate novel capsids, or TRACER Capsids, and identify associated receptors to potentially enable high brain penetration with genetic medicines following intravenous, or IV, dosing. Its segment is developing and commercializing genetic medicine.
54GF Score

Get the complete analysis for MEX:VYGR

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN63.00
Price
MXN32.88
GF Value