Lumosa Therapeutics Co (ROCO:6535) Cyclically Adjusted PB Ratio: 8.23 (As of Aug. 10, 2026) — 53% Below Median

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ROCO:6535 Lumosa Therapeutics Co Ltd ROCO:6535
70 GF Score
Price NT$91.10
GF Value NT$128.00
Valuation Modestly Undervalued
! 3 Warning Signs
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What is Lumosa Therapeutics Co Cyclically Adjusted PB Ratio?

Lumosa Therapeutics Co ROCO:6535 +1.11% 70 Cyclically Adjusted PB Ratio is 8.23 as of Aug. 10, 2026, which is 53% below its 10-year median of 17.37. GuruFocus rates ROCO:6535 with a GF Score™ of 70/100 and a GF Value™ of NT$128.00 (Modestly Undervalued). The stock has 3 warning signs investors should review. Among 692 Biotechnology companies, Lumosa Therapeutics Co ranks worse than 85.55% on this metric.

As of today (2026-08-10), Lumosa Therapeutics Co's current share price is NT$91.10. Lumosa Therapeutics Co's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was NT$11.07. Lumosa Therapeutics Co's Cyclically Adjusted PB Ratio for today is 8.23.

The historical rank and industry rank for Lumosa Therapeutics Co's Cyclically Adjusted PB Ratio or its related term are showing as below:

ROCO:6535' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 7.86   Med: 17.37   Max: 35.92
Current: 8.23

During the past years, Lumosa Therapeutics Co's highest Cyclically Adjusted PB Ratio was 35.92. The lowest was 7.86. And the median was 17.37.

ROCO:6535's Cyclically Adjusted PB Ratio is ranked worse than
85.55% of 692 companies
in the Biotechnology industry
Industry Median: 1.615 vs ROCO:6535: 8.23

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Lumosa Therapeutics Co's adjusted book value per share data for the three months ended in Mar. 2026 was NT$8.328. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is NT$11.07 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Lumosa Therapeutics Co  (ROCO:6535) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Lumosa Therapeutics Co Cyclically Adjusted PB Ratio Related Terms


Lumosa Therapeutics Co Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Lumosa Therapeutics Co's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Lumosa Therapeutics Co Cyclically Adjusted PB Ratio Chart

Lumosa Therapeutics Co Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 23.50 17.92

Lumosa Therapeutics Co Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 16.52 13.52 26.52 17.92 12.92

ROCO:6535 vs VRTX, REGN, RVMD: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Lumosa Therapeutics Co's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Lumosa Therapeutics Co Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Lumosa Therapeutics Co's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Lumosa Therapeutics Co's Cyclically Adjusted PB Ratio falls into.


ROCO:6535
70GF Score
Lumosa Therapeutics Co Ltd ROCO:6535
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Lumosa Therapeutics Co Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Lumosa Therapeutics Co's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=91.10/11.07
=8.23

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Lumosa Therapeutics Co's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Lumosa Therapeutics Co's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=8.328/330.2130*330.2130
=8.328

Current CPI (Mar. 2026) = 330.2130.

Lumosa Therapeutics Co Quarterly Data

Book Value per Share CPI Adj_Book
201606 5.321 241.018 7.290
201609 9.840 241.428 13.459
201612 9.199 241.432 12.582
201703 8.694 243.801 11.775
201706 8.137 244.955 10.969
201709 7.651 246.819 10.236
201712 7.205 246.524 9.651
201803 7.360 249.554 9.739
201806 7.057 251.989 9.248
201809 6.943 252.439 9.082
201812 10.857 251.233 14.270
201903 10.192 254.202 13.240
201906 10.311 256.143 13.293
201909 9.648 256.759 12.408
201912 8.840 256.974 11.359
202003 7.900 258.115 10.107
202006 7.239 257.797 9.272
202009 6.845 260.280 8.684
202012 10.671 260.474 13.528
202103 11.532 264.877 14.377
202106 10.793 271.696 13.118
202109 13.814 274.310 16.629
202112 12.957 278.802 15.346
202203 11.840 287.504 13.599
202206 10.657 296.311 11.876
202209 9.719 296.808 10.813
202212 9.970 296.797 11.093
202303 10.868 301.836 11.890
202306 9.952 305.109 10.771
202309 9.226 307.789 9.898
202312 8.471 306.746 9.119
202403 7.822 312.332 8.270
202406 8.276 314.175 8.698
202409 6.834 315.301 7.157
202412 11.319 315.605 11.843
202503 10.739 319.799 11.089
202506 9.596 322.561 9.824
202509 9.447 324.800 9.604
202512 8.960 324.054 9.130
202603 8.328 330.213 8.328

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 8.23 mean?
Lumosa Therapeutics Co (ROCO:6535) has a Cyclically Adjusted PB Ratio of 8.23 as of Aug. 10, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Lumosa Therapeutics Co and its competitors. This is 53% below median its historical median of 17.37. Over the past decade, Lumosa Therapeutics Co's Cyclically Adjusted PB Ratio has ranged from 7.86 to 35.92. According to the industry distribution chart, Lumosa Therapeutics Co ranks #592 out of 692 companies in the Biotechnology industry, placing it in the top 85.5%.
Is Lumosa Therapeutics Co's Cyclically Adjusted PB Ratio too high?
Lumosa Therapeutics Co's current Cyclically Adjusted PB Ratio of 8.23 is 53% below median its 10-year median of 17.37. Over the past 10 years, this metric has ranged from a low of 7.86 to a high of 35.92. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.62. Lumosa Therapeutics Co's value of 8.23 is 409.6% above this industry median. Based on the distribution chart, Lumosa Therapeutics Co ranks #592 out of 692 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Lumosa Therapeutics Co has a GF Score™ of 70/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Lumosa Therapeutics Co's Cyclically Adjusted PB Ratio compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Lumosa Therapeutics Co ranks #592 out of 692 companies for Cyclically Adjusted PB Ratio. This places Lumosa Therapeutics Co in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.62. Lumosa Therapeutics Co's value of 8.23 is 409.6% above this benchmark. Historically, Lumosa Therapeutics Co's own Cyclically Adjusted PB Ratio has ranged from 7.86 to 35.92 over the past decade. While the company's 10-year median is 17.37 vs. the industry median of 1.62, Lumosa Therapeutics Co has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.62, based on 692 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Lumosa Therapeutics Co's current Cyclically Adjusted PB Ratio of 8.23 is 409.6% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Lumosa Therapeutics Co and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.62 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Lumosa Therapeutics Co's current Cyclically Adjusted PB Ratio is 8.23, which is 53% below median its own 10-year median of 17.37. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Lumosa Therapeutics Co stock overvalued right now?
Based on GuruFocus' analysis, Lumosa Therapeutics Co (ROCO:6535) is currently considered Modestly Undervalued. The stock's GF Value™ is NT$128.00, compared to a current price of NT$91.10 — trading 28.8% below its estimated fair value. The current Cyclically Adjusted PB Ratio is 8.23, which is 53% below median its 10-year median of 17.37 and 409.6% above the Biotechnology industry median of 1.62. Lumosa Therapeutics Co's overall GF Score™ is 70/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Lumosa Therapeutics Co (ROCO:6535), the current Cyclically Adjusted PB Ratio is 8.23 as of Aug. 10, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Lumosa Therapeutics Co (ROCO:6535) Overvalued in 2026?

Based on GuruFocus' analysis, Lumosa Therapeutics Co stock appears to be undervalued. The current stock price of NT$91.10 is trading 28.8% below its estimated GF Value™ of NT$128.00. GuruFocus considers Lumosa Therapeutics Co to be Modestly Undervalued.

Key valuation signals for ROCO:6535:

  • Cyclically Adjusted PB Ratio: 8.23 (53% below median its 10-year median of 17.37)
  • GF Value™: NT$128.00 vs. price of NT$91.10 (28.8% below fair value)
  • GF Score™: 70/100 with 3 warning signs
  • Industry Position: 409.6% above the Biotechnology median (#592 of 692)

No single metric tells the full story. See the ROCO:6535 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Lumosa Therapeutics Co Business Description

Address Park Street, 4th Floor, No. 3-2, Nangang District, Taipei, TWN, 11503
Lumosa Therapeutics Co Ltd develops new drugs. The company is engaged in the development of drugs for unmet medical needs in the fields of oncology and Neuroscience. Geographically, it derives a majority of its revenue from Taiwan and also has a presence in Asia, and America. The product pipeline of the company is Neuroscience, which includes LT 1001 for Postoperative Pain, LT 3001 for Acute Ischemic Stroke, LT 5001 for Uremic Pruritus, LT 6001 for Neurological disorder, and Oncology, including LT 2003 for Solid Tumor. It generates revenue from sales of goods.
70GF Score

Get the complete analysis for ROCO:6535

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

NT$91.10
Price
NT$128.00
GF Value