Zhongyuan Union Cell & Gene Engineering (SHSE:600645) Cyclically Adjusted PB Ratio: 3.17 (As of Aug. 18, 2026) — 39% Below Median

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

SHSE:600645 Zhongyuan Union Cell & Gene Engineering Corp Ltd SHSE:600645
65 GF Score
Price ¥22.41
GF Value ¥20.92
Valuation Fairly Valued
! 2 Warning Signs
View Full Analysis

What is Zhongyuan Union Cell & Gene Engineering Cyclically Adjusted PB Ratio?

Zhongyuan Union Cell & Gene Engineering SHSE:600645 +4.82% 65 Cyclically Adjusted PB Ratio is 3.17 as of Aug. 18, 2026, which is 39% below its 10-year median of 5.17. GuruFocus rates SHSE:600645 with a GF Score™ of 65/100 and a GF Value™ of ¥20.92 (Fairly Valued). The stock has 2 warning signs investors should review. Among 692 Biotechnology companies, Zhongyuan Union Cell & Gene Engineering ranks worse than 65.03% on this metric.

As of today (2026-08-18), Zhongyuan Union Cell & Gene Engineering's current share price is ¥22.41. Zhongyuan Union Cell & Gene Engineering's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was ¥7.08. Zhongyuan Union Cell & Gene Engineering's Cyclically Adjusted PB Ratio for today is 3.17.

The historical rank and industry rank for Zhongyuan Union Cell & Gene Engineering's Cyclically Adjusted PB Ratio or its related term are showing as below:

SHSE:600645' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 2.36   Med: 5.17   Max: 31.73
Current: 3.15

During the past years, Zhongyuan Union Cell & Gene Engineering's highest Cyclically Adjusted PB Ratio was 31.73. The lowest was 2.36. And the median was 5.17.

SHSE:600645's Cyclically Adjusted PB Ratio is ranked worse than
65.03% of 692 companies
in the Biotechnology industry
Industry Median: 1.635 vs SHSE:600645: 3.15

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Zhongyuan Union Cell & Gene Engineering's adjusted book value per share data for the three months ended in Mar. 2026 was ¥7.948. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is ¥7.08 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Zhongyuan Union Cell & Gene Engineering  (SHSE:600645) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Zhongyuan Union Cell & Gene Engineering Cyclically Adjusted PB Ratio Related Terms


Zhongyuan Union Cell & Gene Engineering Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Zhongyuan Union Cell & Gene Engineering's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Zhongyuan Union Cell & Gene Engineering Cyclically Adjusted PB Ratio Chart

Zhongyuan Union Cell & Gene Engineering Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 5.55 3.20 3.38 2.94 3.62

Zhongyuan Union Cell & Gene Engineering Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 3.46 3.44 3.60 3.62 4.36

SHSE:600645 vs VRTX, REGN, RVMD: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Zhongyuan Union Cell & Gene Engineering's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Zhongyuan Union Cell & Gene Engineering Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Zhongyuan Union Cell & Gene Engineering's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Zhongyuan Union Cell & Gene Engineering's Cyclically Adjusted PB Ratio falls into.


SHSE:600645
65GF Score
Zhongyuan Union Cell & Gene Engineering Corp Ltd SHSE:600645
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Zhongyuan Union Cell & Gene Engineering Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Zhongyuan Union Cell & Gene Engineering's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=22.41/7.08
=3.17

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Zhongyuan Union Cell & Gene Engineering's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Zhongyuan Union Cell & Gene Engineering's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=7.948/116.3033*116.3033
=7.948

Current CPI (Mar. 2026) = 116.3033.

Zhongyuan Union Cell & Gene Engineering Quarterly Data

Book Value per Share CPI Adj_Book
201606 4.027 101.400 4.619
201609 3.999 102.400 4.542
201612 4.113 102.600 4.662
201703 3.962 103.200 4.465
201706 3.892 103.100 4.390
201709 3.851 104.100 4.302
201712 7.141 104.500 7.948
201803 4.102 105.300 4.531
201806 4.517 104.900 5.008
201809 6.839 106.600 7.462
201812 6.293 106.500 6.872
201903 6.354 107.700 6.862
201906 6.523 107.700 7.044
201909 7.161 109.800 7.585
201912 7.166 111.200 7.495
202003 7.193 112.300 7.449
202006 7.673 110.400 8.083
202009 7.724 111.700 8.042
202012 7.298 111.500 7.612
202103 7.682 112.662 7.930
202106 7.748 111.769 8.062
202109 7.665 112.215 7.944
202112 7.401 113.108 7.610
202203 7.310 114.335 7.436
202206 7.432 114.558 7.545
202209 7.578 115.339 7.641
202212 7.599 115.116 7.677
202303 7.644 115.116 7.723
202306 7.819 114.558 7.938
202309 7.905 115.339 7.971
202312 7.873 114.781 7.977
202403 7.822 115.227 7.895
202406 7.709 114.781 7.811
202409 7.728 115.785 7.763
202412 7.683 114.893 7.777
202503 7.739 115.116 7.819
202506 7.801 114.907 7.896
202509 7.931 115.471 7.988
202512 7.921 115.832 7.953
202603 7.948 116.303 7.948

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 3.17 mean?
Zhongyuan Union Cell & Gene Engineering (SHSE:600645) has a Cyclically Adjusted PB Ratio of 3.17 as of Aug. 18, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Zhongyuan Union Cell & Gene Engineering and its competitors. This is 39% below median its historical median of 5.17. Over the past decade, Zhongyuan Union Cell & Gene Engineering's Cyclically Adjusted PB Ratio has ranged from 2.36 to 31.73. According to the industry distribution chart, Zhongyuan Union Cell & Gene Engineering ranks #450 out of 692 companies in the Biotechnology industry, placing it in the top 65%.
Is Zhongyuan Union Cell & Gene Engineering's Cyclically Adjusted PB Ratio too high?
Zhongyuan Union Cell & Gene Engineering's current Cyclically Adjusted PB Ratio of 3.17 is 39% below median its 10-year median of 5.17. Over the past 10 years, this metric has ranged from a low of 2.36 to a high of 31.73. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.64. Zhongyuan Union Cell & Gene Engineering's value of 3.17 is 93.9% above this industry median. Based on the distribution chart, Zhongyuan Union Cell & Gene Engineering ranks #450 out of 692 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Zhongyuan Union Cell & Gene Engineering has a GF Score™ of 65/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Zhongyuan Union Cell & Gene Engineering's Cyclically Adjusted PB Ratio compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Zhongyuan Union Cell & Gene Engineering ranks #450 out of 692 companies for Cyclically Adjusted PB Ratio. This places Zhongyuan Union Cell & Gene Engineering in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.64. Zhongyuan Union Cell & Gene Engineering's value of 3.17 is 93.9% above this benchmark. Historically, Zhongyuan Union Cell & Gene Engineering's own Cyclically Adjusted PB Ratio has ranged from 2.36 to 31.73 over the past decade. While the company's 10-year median is 5.17 vs. the industry median of 1.64, Zhongyuan Union Cell & Gene Engineering has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.64, based on 692 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Zhongyuan Union Cell & Gene Engineering's current Cyclically Adjusted PB Ratio of 3.17 is 93.9% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Zhongyuan Union Cell & Gene Engineering and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.64 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Zhongyuan Union Cell & Gene Engineering's current Cyclically Adjusted PB Ratio is 3.17, which is 39% below median its own 10-year median of 5.17. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Zhongyuan Union Cell & Gene Engineering stock overvalued right now?
Based on GuruFocus' analysis, Zhongyuan Union Cell & Gene Engineering (SHSE:600645) is currently considered Fairly Valued. The stock's GF Value™ is ¥20.92, compared to a current price of ¥22.41 — trading 7.1% above its estimated fair value. The current Cyclically Adjusted PB Ratio is 3.17, which is 39% below median its 10-year median of 5.17 and 93.9% above the Biotechnology industry median of 1.64. Zhongyuan Union Cell & Gene Engineering's overall GF Score™ is 65/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Zhongyuan Union Cell & Gene Engineering (SHSE:600645), the current Cyclically Adjusted PB Ratio is 3.17 as of Aug. 18, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Zhongyuan Union Cell & Gene Engineering (SHSE:600645) Overvalued in 2026?

Based on GuruFocus' analysis, Zhongyuan Union Cell & Gene Engineering stock appears to be overvalued. The current stock price of ¥22.41 is trading 7.1% above its estimated GF Value™ of ¥20.92. GuruFocus considers Zhongyuan Union Cell & Gene Engineering to be Fairly Valued.

Key valuation signals for SHSE:600645:

  • Cyclically Adjusted PB Ratio: 3.17 (39% below median its 10-year median of 5.17)
  • GF Value™: ¥20.92 vs. price of ¥22.41 (7.1% above fair value)
  • GF Score™: 65/100 with 2 warning signs
  • Industry Position: 93.9% above the Biotechnology median (#450 of 692)

No single metric tells the full story. See the SHSE:600645 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Zhongyuan Union Cell & Gene Engineering Business Description

Address 45 East of Tianjin Airport Economic Zone nine, Tianjin, CHN, 300304
Zhongyuan Union Cell & Gene Engineering Corp Ltd is engaged in stem cell technology research, as well as detection and storage sources of stem cells in China. The company insists on the core strategy upon dual-core development of 'cell + gene' with the major businesses covering various cell storage businesses of newborns and adults; the preparation and storage of cord blood hematopoietic stem cells, umbilical cord mesenchymal stem cells, placental pluripotent stem cells, adipose-derived stem cells and immune cells; genetic testing services relating to children's genes.
65GF Score

Get the complete analysis for SHSE:600645

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

¥22.41
Price
¥20.92
GF Value