Kala Bio (STU:27F) Cyclically Adjusted PB Ratio: 0.07 (As of Aug. 11, 2026)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

STU:27F Kala Bio Inc STU:27F
18 GF Score
Price €3.14
! 2 Warning Signs
View Full Analysis

What is Kala Bio Cyclically Adjusted PB Ratio?

Kala Bio STU:27F 18 Cyclically Adjusted PB Ratio is 0.07 as of Aug. 11, 2026. GuruFocus rates STU:27F with a GF Score™ of 18/100. The stock has 2 warning signs investors should review. Among 692 Biotechnology companies, Kala Bio ranks worse than 144508.53% on this metric.

As of today (2026-08-11), Kala Bio's current share price is €3.14. Kala Bio's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was €43.17. Kala Bio's Cyclically Adjusted PB Ratio for today is 0.07.

The historical rank and industry rank for Kala Bio's Cyclically Adjusted PB Ratio or its related term are showing as below:

STU:27F's Cyclically Adjusted PB Ratio is not ranked *
in the Biotechnology industry.
Industry Median: 1.615
* Ranked among companies with meaningful Cyclically Adjusted PB Ratio only.

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Kala Bio's adjusted book value per share data for the three months ended in Mar. 2026 was €0.501. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is €43.17 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Kala Bio  (STU:27F) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Kala Bio Cyclically Adjusted PB Ratio Related Terms


Kala Bio Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Kala Bio's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Kala Bio Cyclically Adjusted PB Ratio Chart

Kala Bio Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.01

Kala Bio Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.03 0.01 0.00

STU:27F vs GDTC, GTBP, INAB: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Kala Bio's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Kala Bio Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Kala Bio's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Kala Bio's Cyclically Adjusted PB Ratio falls into.


STU:27F
18GF Score
Kala Bio Inc STU:27F
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Kala Bio Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Kala Bio's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=3.14/43.17
=0.07

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Kala Bio's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Kala Bio's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=0.501/330.2130*330.2130
=0.501

Current CPI (Mar. 2026) = 330.2130.

Kala Bio Quarterly Data

Book Value per Share CPI Adj_Book
201606 0.000 241.018 0.000
201609 0.000 241.428 0.000
201612 -9,244.222 241.432 -12,643.570
201703 2,334.111 243.801 3,161.405
201706 -10,622.556 244.955 -14,319.798
201709 8,294.600 246.819 11,097.139
201712 7,577.900 246.524 10,150.416
201803 6,510.000 249.554 8,614.114
201806 5,828.800 251.989 7,638.213
201809 4,707.800 252.439 6,158.227
201812 6,591.143 251.233 8,663.198
201903 5,206.786 254.202 6,763.709
201906 3,860.214 256.143 4,976.489
201909 2,792.500 256.759 3,591.383
201912 1,908.786 256.974 2,452.800
202003 5,821.227 258.115 7,447.242
202006 5,204.591 257.797 6,666.577
202009 4,091.773 260.280 5,191.166
202012 3,424.833 260.474 4,341.794
202103 3,547.115 264.877 4,422.066
202106 2,690.154 271.696 3,269.551
202109 2,009.577 274.310 2,419.119
202112 572.000 278.802 677.477
202203 -165.448 287.504 -190.025
202206 -1,029.310 296.311 -1,147.077
202209 -32.600 296.808 -36.269
202212 526.794 296.797 586.105
202303 476.370 301.836 521.156
202306 316.569 305.109 342.616
202309 194.741 307.789 208.929
202312 125.109 306.746 134.680
202403 109.429 312.332 115.694
202406 138.511 314.175 145.582
202409 67.174 315.301 70.351
202412 96.533 315.605 101.001
202503 40.930 319.799 42.263
202506 -20.746 322.561 -21.238
202509 -49.550 324.800 -50.376
202512 10.725 324.054 10.929
202603 0.501 330.213 0.501

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 0.07 mean?
Kala Bio (STU:27F) has a Cyclically Adjusted PB Ratio of 0.07 as of Aug. 11, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Kala Bio and its competitors. According to the industry distribution chart, Kala Bio ranks #999999 out of 692 companies in the Biotechnology industry.
Is Kala Bio's Cyclically Adjusted PB Ratio too high?
Kala Bio's current Cyclically Adjusted PB Ratio is 0.07. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.62. Kala Bio's value of 0.07 is 95.7% below this industry median. Based on the distribution chart, Kala Bio ranks #999999 out of 692 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Kala Bio has a GF Score™ of 18/100, reflecting its overall financial health beyond just this single metric.
How does Kala Bio's Cyclically Adjusted PB Ratio compare to GDTC and GTBP?
According to the Biotechnology industry distribution chart, Kala Bio ranks #999999 out of 692 companies for Cyclically Adjusted PB Ratio. This places Kala Bio in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.62. Kala Bio's value of 0.07 is 95.7% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.62, based on 692 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Kala Bio's current Cyclically Adjusted PB Ratio of 0.07 is 95.7% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Kala Bio and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.62 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Kala Bio's current Cyclically Adjusted PB Ratio is 0.07. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Kala Bio stock overvalued right now?
Kala Bio (STU:27F) has a current Cyclically Adjusted PB Ratio of 0.07. The current Cyclically Adjusted PB Ratio is 0.07 and 95.7% below the Biotechnology industry median of 1.62. Kala Bio's overall GF Score™ is 18/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Kala Bio (STU:27F), the current Cyclically Adjusted PB Ratio is 0.07 as of Aug. 11, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Kala Bio Business Description

Other Exchanges KALA:USA0JQ2:UK
Address 1167 Massachusetts Avenue, Arlington, MA, USA, 02476
Kala Bio Inc is a clinical-stage biopharmaceutical company dedicated to the research, development and commercialization of inventive therapies for rare and severe diseases of the front and back of the eye. It main product candidate, KPI-012, is a human MSC-S, which contains numerous human-derived biofactors, such as growth factors, protease inhibitors, matrix proteins, and neurotrophic factors that can potentially correct the impaired corneal healing that is an underlying etiology of multiple severe ocular diseases. Its MSC-S platform is for retinal degenerative diseases, such as Retinitis Pigmentosa and Stargardt Disease.
18GF Score

Get the complete analysis for STU:27F

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€3.14
Price