Exicure (STU:2H0) Cyclically Adjusted PB Ratio: 0.02 (As of Aug. 24, 2026)

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STU:2H0 Exicure Inc STU:2H0
32 GF Score
Price €0.99
! 3 Warning Signs
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What is Exicure Cyclically Adjusted PB Ratio?

Exicure STU:2H0 -4.50% 32 Cyclically Adjusted PB Ratio is 0.02 as of Aug. 24, 2026. GuruFocus rates STU:2H0 with a GF Score™ of 32/100. The stock has 3 warning signs investors should review. Among 685 Biotechnology companies, Exicure ranks better than 97.23% on this metric.

As of today (2026-08-24), Exicure's current share price is €0.985. Exicure's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 was €43.16. Exicure's Cyclically Adjusted PB Ratio for today is 0.02.

The historical rank and industry rank for Exicure's Cyclically Adjusted PB Ratio or its related term are showing as below:

STU:2H0' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0   Med: 0   Max: 0.02
Current: 0.02

During the past years, Exicure's highest Cyclically Adjusted PB Ratio was 0.02. The lowest was 0.00. And the median was 0.00.

STU:2H0's Cyclically Adjusted PB Ratio is ranked better than
97.23% of 685 companies
in the Biotechnology industry
Industry Median: 1.62 vs STU:2H0: 0.02

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Exicure's adjusted book value per share data for the three months ended in Jun. 2026 was €0.133. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is €43.16 for the trailing ten years ended in Jun. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Exicure  (STU:2H0) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Exicure Cyclically Adjusted PB Ratio Related Terms


Exicure Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Exicure's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Exicure Cyclically Adjusted PB Ratio Chart

Exicure Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.00

Exicure Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.04

STU:2H0 vs AEON, LNAI, PBM: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, Exicure's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Exicure Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Exicure's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Exicure's Cyclically Adjusted PB Ratio falls into.


STU:2H0
32GF Score
Exicure Inc STU:2H0
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Exicure Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Exicure's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=0.985/43.16
=0.02

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Exicure's Cyclically Adjusted Book per Share for the quarter that ended in Jun. 2026 is calculated as:

For example, Exicure's adjusted Book Value per Share data for the three months ended in Jun. 2026 was:

Adj_Book=Book Value per Share/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=0.133/333.9520*333.9520
=0.133

Current CPI (Jun. 2026) = 333.9520.

Exicure Quarterly Data

Book Value per Share CPI Adj_Book
201609 0.000 241.428 0.000
201612 -144.837 241.432 -200.340
201703 0.000 243.801 0.000
201706 0.000 244.955 0.000
201709 37.266 246.819 50.422
201712 64.179 246.524 86.940
201803 50.289 249.554 67.297
201806 32.228 251.989 42.711
201809 72.956 252.439 96.514
201812 62.220 251.233 82.706
201903 48.301 254.202 63.454
201906 34.057 256.143 44.403
201909 116.323 256.759 151.295
201912 126.606 256.974 164.532
202003 132.578 258.115 171.531
202006 124.950 257.797 161.861
202009 107.113 260.280 137.431
202012 86.572 260.474 110.993
202103 71.608 264.877 90.282
202106 51.807 271.696 63.678
202109 20.249 274.310 24.652
202112 13.710 278.802 16.422
202203 3.587 287.504 4.167
202206 1.109 296.311 1.250
202209 -3.766 296.808 -4.237
202212 14.185 296.797 15.961
202303 8.157 301.836 9.025
202306 5.178 305.109 5.667
202309 2.436 307.789 2.643
202312 1.606 306.746 1.748
202403 1.173 312.332 1.254
202406 0.866 314.175 0.921
202409 0.641 315.301 0.679
202412 1.073 315.605 1.135
202503 1.666 319.799 1.740
202506 1.216 322.561 1.259
202509 0.926 324.800 0.952
202512 0.526 324.054 0.542
202603 0.285 330.213 0.288
202606 0.133 333.952 0.133

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 0.02 mean?
Exicure (STU:2H0) has a Cyclically Adjusted PB Ratio of 0.02 as of Aug. 24, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Exicure and its competitors. According to the industry distribution chart, Exicure ranks #19 out of 685 companies in the Biotechnology industry, placing it in the top 2.8%.
Is Exicure's Cyclically Adjusted PB Ratio too high?
Exicure's current Cyclically Adjusted PB Ratio is 0.02. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.62. Exicure's value of 0.02 is 98.8% below this industry median. Based on the distribution chart, Exicure ranks #19 out of 685 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Exicure has a GF Score™ of 32/100, reflecting its overall financial health beyond just this single metric.
How does Exicure's Cyclically Adjusted PB Ratio compare to AEON and LNAI?
According to the Biotechnology industry distribution chart, Exicure ranks #19 out of 685 companies for Cyclically Adjusted PB Ratio. This places Exicure in the top 3% of its industry — outperforming the majority of peers. The industry median Cyclically Adjusted PB Ratio is 1.62. Exicure's value of 0.02 is 98.8% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.62, based on 685 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Exicure's current Cyclically Adjusted PB Ratio of 0.02 is 98.8% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Exicure and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.62 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Exicure's current Cyclically Adjusted PB Ratio is 0.02. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Exicure stock overvalued right now?
Exicure (STU:2H0) has a current Cyclically Adjusted PB Ratio of 0.02. The current Cyclically Adjusted PB Ratio is 0.02 and 98.8% below the Biotechnology industry median of 1.62. Exicure's overall GF Score™ is 32/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Exicure (STU:2H0), the current Cyclically Adjusted PB Ratio is 0.02 as of Aug. 24, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Exicure Business Description

Other Exchanges XCUR:USA
Address 400 Seaport Court, Suite 102, Redwood City, CA, USA, 94063
Exicure Inc is a clinical-stage biotechnology company focused on developing treatments for blood-related diseases, with an emphasis on small-molecule therapies that have the potential to benefit a broad range of patients. The company acquired GPCR Therapeutics USA and secured a license for GPC-100 (Burixafor), a clinical-stage small-molecule compound that inhibits the chemokine receptor CXCR4. GPC-100 has demonstrated the ability to effectively mobilize various cell types, including hematopoietic stem cells and lymphocytes, highlighting its broad therapeutic potential across multiple indications.
32GF Score

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Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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