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Thermo Fisher ScientificTMO +1.17%85 Cyclically Adjusted PB Ratio is 5.21 as of Aug. 03, 2026, which is 7% below its 10-year median of 5.59. GuruFocus rates TMO with a GF Score™ of 85/100 and a GF Value™ of $592.55 (Fairly Valued). The stock has 8 warning signs investors should review. Among 131 Medical Diagnostics & Research companies, Thermo Fisher Scientific ranks worse than 83.21% on this metric.
The historical rank and industry rank for Thermo Fisher Scientific's Cyclically Adjusted PB Ratio or its related term are showing as below:
TMO'
s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 3.11 Med: 5.59 Max: 9.75
Current: 5.15
During the past years, Thermo Fisher Scientific's highest Cyclically Adjusted PB Ratio was 9.75. The lowest was 3.11. And the median was 5.59.
TMO's Cyclically Adjusted PB Ratio is ranked worse than 83.21% of 131
companies
in the Medical Diagnostics & Research industry
Industry Median: 1.75
vs TMO: 5.15
The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.
Thermo Fisher Scientific's adjusted book value per share data for the three months ended in Jun. 2026 was $141.773. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is $111.46 for the trailing ten years ended in Jun. 2026.
Shiller PE for Stocks: The True Measure of Stock Valuation
Thermo Fisher Scientific (NYSE:TMO) Cyclically Adjusted PB Ratio Explanation
Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.
If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.
Thermo Fisher Scientific Cyclically Adjusted PB Ratio Related Terms
Thermo Fisher Scientific Cyclically Adjusted PB Ratio Historical Data
* Premium members only.
The historical data trend for Thermo Fisher Scientific's Cyclically Adjusted PB Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Thermo Fisher Scientific Cyclically Adjusted PB Ratio Chart
TMO vs DHR, IDXX, A: Cyclically Adjusted PB Ratio Comparison
For the Diagnostics & Research subindustry, Thermo Fisher Scientific's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Thermo Fisher Scientific Cyclically Adjusted PB Ratio vs Medical Diagnostics & Research Industry
For the Medical Diagnostics & Research industry and Healthcare sector, Thermo Fisher Scientific's Cyclically Adjusted PB Ratio distribution charts can be found below:
* The bar in red indicates where Thermo Fisher Scientific's Cyclically Adjusted PB Ratio falls into.
Thermo Fisher Scientific Cyclically Adjusted PB Ratio Calculation
Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.
The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.
What does a Cyclically Adjusted PB Ratio of 5.21 mean?
Thermo Fisher Scientific (TMO) has a Cyclically Adjusted PB Ratio of 5.21 as of Aug. 03, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Thermo Fisher Scientific and its competitors. This is near median its historical median of 5.59. Over the past decade, Thermo Fisher Scientific's Cyclically Adjusted PB Ratio has ranged from 3.11 to 9.75. According to the industry distribution chart, Thermo Fisher Scientific ranks #109 out of 131 companies in the Medical Diagnostics & Research industry, placing it in the top 83.2%.
Is Thermo Fisher Scientific's Cyclically Adjusted PB Ratio too high?
Thermo Fisher Scientific's current Cyclically Adjusted PB Ratio of 5.21 is near median its 10-year median of 5.59. Over the past 10 years, this metric has ranged from a low of 3.11 to a high of 9.75. The Medical Diagnostics & Research industry median Cyclically Adjusted PB Ratio is 1.75. Thermo Fisher Scientific's value of 5.21 is 197.7% above this industry median. Based on the distribution chart, Thermo Fisher Scientific ranks #109 out of 131 companies in the Medical Diagnostics & Research industry, which is in the bottom quartile relative to peers. Overall, Thermo Fisher Scientific has a GF Score™ of 85/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Thermo Fisher Scientific's Cyclically Adjusted PB Ratio compare to DHR and IDXX?
According to the Medical Diagnostics & Research industry distribution chart, Thermo Fisher Scientific ranks #109 out of 131 companies for Cyclically Adjusted PB Ratio. This places Thermo Fisher Scientific in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.75. Thermo Fisher Scientific's value of 5.21 is 197.7% above this benchmark. Historically, Thermo Fisher Scientific's own Cyclically Adjusted PB Ratio has ranged from 3.11 to 9.75 over the past decade. While the company's 10-year median is 5.59 vs. the industry median of 1.75, Thermo Fisher Scientific has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Medical Diagnostics & Research company?
The median Cyclically Adjusted PB Ratio among Medical Diagnostics & Research companies is 1.75, based on 131 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Thermo Fisher Scientific's current Cyclically Adjusted PB Ratio of 5.21 is 197.7% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Thermo Fisher Scientific and its competitors. For the Medical Diagnostics & Research industry, the median Cyclically Adjusted PB Ratio is 1.75 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Thermo Fisher Scientific's current Cyclically Adjusted PB Ratio is 5.21, which is near median its own 10-year median of 5.59. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Thermo Fisher Scientific stock overvalued right now?
Based on GuruFocus' analysis, Thermo Fisher Scientific (TMO) is currently considered Fairly Valued. The stock's GF Value™ is $592.55, compared to a current price of $581.02 — trading 1.9% below its estimated fair value. The current Cyclically Adjusted PB Ratio is 5.21, which is near median its 10-year median of 5.59 and 197.7% above the Medical Diagnostics & Research industry median of 1.75. Thermo Fisher Scientific's overall GF Score™ is 85/100 with 8 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Thermo Fisher Scientific (TMO), the current Cyclically Adjusted PB Ratio is 5.21 as of Aug. 03, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Thermo Fisher Scientific (TMO) Overvalued in 2026?
Based on GuruFocus' analysis, Thermo Fisher Scientific stock appears to be undervalued.
The current stock price of $581.02 is trading 1.9% below its estimated GF Value™ of $592.55.
GuruFocus considers Thermo Fisher Scientific to be Fairly Valued.
Key valuation signals for TMO:
Cyclically Adjusted PB Ratio: 5.21 (near median its 10-year median of 5.59)
GF Value™: $592.55 vs. price of $581.02 (1.9% below fair value)
Industry Position: 197.7% above the Medical Diagnostics & Research median (#109 of 131)
No single metric tells the full story. See the TMO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Thermo Fisher Scientific sells scientific instruments and laboratory equipment, diagnostics consumables, and life science reagents. The firm operates through four segments as of year-end 2025 (revenue figures include some cross-segment revenue): analytical technologies (17% of sales); specialty diagnostic products (11%); life science solutions (23%); and lab products and services, which includes CRO services (the remainder).
85GF Score
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