SanBio Co (TSE:4592) Cyclically Adjusted PB Ratio: 8.81 (As of Aug. 05, 2026)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

TSE:4592 SanBio Co Ltd TSE:4592
23 GF Score
Price 円971.00
! 1 Warning Sign
View Full Analysis

What is SanBio Co Cyclically Adjusted PB Ratio?

SanBio Co TSE:4592 +3.52% 23 Cyclically Adjusted PB Ratio is 8.81 as of Aug. 05, 2026. GuruFocus rates TSE:4592 with a GF Score™ of 23/100. The stock has 1 warning sign investors should review. Among 696 Biotechnology companies, SanBio Co ranks worse than 86.49% on this metric.

As of today (2026-08-05), SanBio Co's current share price is 円971.00. SanBio Co's Cyclically Adjusted Book per Share for the quarter that ended in Jan. 2026 was 円110.21. SanBio Co's Cyclically Adjusted PB Ratio for today is 8.81.

The historical rank and industry rank for SanBio Co's Cyclically Adjusted PB Ratio or its related term are showing as below:

TSE:4592' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 0   Med: 0   Max: 8.68
Current: 8.68

During the past years, SanBio Co's highest Cyclically Adjusted PB Ratio was 8.68. The lowest was 0.00. And the median was 0.00.

TSE:4592's Cyclically Adjusted PB Ratio is ranked worse than
86.49% of 696 companies
in the Biotechnology industry
Industry Median: 1.585 vs TSE:4592: 8.68

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

SanBio Co's adjusted book value per share data for the three months ended in Jan. 2026 was 円174.345. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is 円110.21 for the trailing ten years ended in Jan. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


SanBio Co  (TSE:4592) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


SanBio Co Cyclically Adjusted PB Ratio Related Terms


SanBio Co Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for SanBio Co's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

SanBio Co Cyclically Adjusted PB Ratio Chart

SanBio Co Annual Data
Trend Jan17 Jan18 Jan19 Jan20 Jan21 Jan22 Jan23 Jan24 Jan25 Jan26
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 5.98 16.78

SanBio Co Quarterly Data
Jul21 Oct21 Jan22 Apr22 Jul22 Oct22 Jan23 Apr23 Jul23 Oct23 Jan24 Apr24 Jul24 Oct24 Jan25 Apr25 Jul25 Oct25 Jan26 Apr26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 17.10 20.45 25.76 16.78 0.00

TSE:4592 vs VRTX, REGN, RVMD: Cyclically Adjusted PB Ratio Comparison

For the Biotechnology subindustry, SanBio Co's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


SanBio Co Cyclically Adjusted PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, SanBio Co's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where SanBio Co's Cyclically Adjusted PB Ratio falls into.


TSE:4592
23GF Score
SanBio Co Ltd TSE:4592
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

SanBio Co Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

SanBio Co's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=971.00/110.21
=8.81

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

SanBio Co's Cyclically Adjusted Book per Share for the quarter that ended in Jan. 2026 is calculated as:

For example, SanBio Co's adjusted Book Value per Share data for the three months ended in Jan. 2026 was:

Adj_Book=Book Value per Share/CPI of Jan. 2026 (Change)*Current CPI (Jan. 2026)
=174.345/112.9000*112.9000
=174.345

Current CPI (Jan. 2026) = 112.9000.

SanBio Co Quarterly Data

Book Value per Share CPI Adj_Book
201604 136.753 98.100 157.384
201607 118.835 97.900 137.043
201610 106.775 98.600 122.261
201701 101.864 98.200 117.112
201704 78.472 98.500 89.944
201707 53.189 98.300 61.089
201710 31.745 98.800 36.275
201801 18.756 99.500 21.282
201804 74.426 99.100 84.790
201807 217.473 99.200 247.507
201810 204.922 100.200 230.895
201901 179.139 99.700 202.857
201904 161.438 100.000 182.264
201907 268.117 99.800 303.311
201910 245.121 100.400 275.639
202001 211.069 100.500 237.111
202004 188.253 100.200 212.113
202007 174.180 100.000 196.649
202010 164.026 99.800 185.556
202101 161.242 99.800 182.407
202104 133.243 99.100 151.798
202107 107.209 99.700 121.403
202110 75.258 99.900 85.051
202201 39.294 100.300 44.230
202204 44.699 101.500 49.719
202207 65.969 102.300 72.804
202210 27.985 103.700 30.468
202301 69.120 104.700 74.533
202304 59.216 105.100 63.611
202307 34.316 105.700 36.654
202310 28.666 107.100 30.218
202401 41.108 106.900 43.415
202404 34.965 107.700 36.653
202407 22.905 108.600 23.812
202410 8.985 109.500 9.264
202501 24.855 111.200 25.235
202504 26.314 111.500 26.644
202507 17.968 111.900 18.129
202510 6.833 112.800 6.839
202601 174.345 112.900 174.345

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 8.81 mean?
SanBio Co (TSE:4592) has a Cyclically Adjusted PB Ratio of 8.81 as of Aug. 05, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on SanBio Co and its competitors. According to the industry distribution chart, SanBio Co ranks #602 out of 696 companies in the Biotechnology industry, placing it in the top 86.5%.
Is SanBio Co's Cyclically Adjusted PB Ratio too high?
SanBio Co's current Cyclically Adjusted PB Ratio is 8.81. The Biotechnology industry median Cyclically Adjusted PB Ratio is 1.59. SanBio Co's value of 8.81 is 455.8% above this industry median. Based on the distribution chart, SanBio Co ranks #602 out of 696 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, SanBio Co has a GF Score™ of 23/100, reflecting its overall financial health beyond just this single metric.
How does SanBio Co's Cyclically Adjusted PB Ratio compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, SanBio Co ranks #602 out of 696 companies for Cyclically Adjusted PB Ratio. This places SanBio Co in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.59. SanBio Co's value of 8.81 is 455.8% above this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Biotechnology company?
The median Cyclically Adjusted PB Ratio among Biotechnology companies is 1.59, based on 696 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. SanBio Co's current Cyclically Adjusted PB Ratio of 8.81 is 455.8% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on SanBio Co and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PB Ratio is 1.59 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. SanBio Co's current Cyclically Adjusted PB Ratio is 8.81. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is SanBio Co stock overvalued right now?
SanBio Co (TSE:4592) has a current Cyclically Adjusted PB Ratio of 8.81. The current Cyclically Adjusted PB Ratio is 8.81 and 455.8% above the Biotechnology industry median of 1.59. SanBio Co's overall GF Score™ is 23/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For SanBio Co (TSE:4592), the current Cyclically Adjusted PB Ratio is 8.81 as of Aug. 05, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

SanBio Co Business Description

Address 8-1 Street Luke Tower 32nd Floor, Akashi-cho, Chuo-ku, Tokyo, JPN, 104-0044
SanBio Co Ltd is engaged in the research and development of regenerative cells drugs. The company has three types of drugs under development, including nerve regeneration cell SB623, used for the treatment of chronic cerebral infarction, traumatic brain injury, age-related macular degeneration, retinitis pigmentosa, Parkinson's disease, spinal cord injury and Alzheimer's disease; enhanced type-mesenchymal stem cells SB618, used to treat peripheral neuropathy, as well as muscle stem cells SB308, used in the treatment of muscular dystrophy.
23GF Score

Get the complete analysis for TSE:4592

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円971.00
Price