Biogen (XSWX:BIIB) Cyclically Adjusted PB Ratio: 2.28 (As of Jul. 25, 2026) — 53% Below Median

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XSWX:BIIB Biogen Inc XSWX:BIIB
74 GF Score
Price CHF173.46
GF Value CHF164.93
! 7 Warning Signs
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What is Biogen Cyclically Adjusted PB Ratio?

Biogen XSWX:BIIB 74 Cyclically Adjusted PB Ratio is 2.28 as of Jul. 25, 2026, which is 53% below its 10-year median of 4.81. GuruFocus rates XSWX:BIIB with a GF Score™ of 74/100 and a GF Value™ of CHF164.93. The stock has 7 warning signs investors should review. Among 756 Drug Manufacturers companies, Biogen ranks worse than 54.76% on this metric.

As of today (2026-07-25), Biogen's current share price is CHF173.46. Biogen's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 was CHF75.96. Biogen's Cyclically Adjusted PB Ratio for today is 2.28.

The historical rank and industry rank for Biogen's Cyclically Adjusted PB Ratio or its related term are showing as below:

XSWX:BIIB' s Cyclically Adjusted PB Ratio Range Over the Past 10 Years
Min: 1.31   Med: 4.81   Max: 9.94
Current: 2.09

During the past years, Biogen's highest Cyclically Adjusted PB Ratio was 9.94. The lowest was 1.31. And the median was 4.81.

XSWX:BIIB's Cyclically Adjusted PB Ratio is ranked worse than
54.76% of 756 companies
in the Drug Manufacturers industry
Industry Median: 1.84 vs XSWX:BIIB: 2.09

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio. The Cyclically Adjusted Book per Share is the average of the inflation adjusted book value per share of a company over the past 10 years.

Biogen's adjusted book value per share data for the three months ended in Mar. 2026 was CHF99.488. Add all the adjusted book value per share for the past 10 years together and divide the count will get our Cyclically Adjusted Book per Share, which is CHF75.96 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Biogen  (XSWX:BIIB) Cyclically Adjusted PB Ratio Explanation

Compared with the regular PB Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PB Ratio smoothed out the fluctuations of book value during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PB Ratio should give similar results to regular PB Ratio.


Biogen Cyclically Adjusted PB Ratio Related Terms


Biogen Cyclically Adjusted PB Ratio Historical Data

* Premium members only.

The historical data trend for Biogen's Cyclically Adjusted PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Biogen Cyclically Adjusted PB Ratio Chart

Biogen Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PB Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 3.93 3.96 3.32 1.79 1.88

Biogen Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1.56 1.40 1.52 1.88 1.90

XSWX:BIIB vs OGN, AMRN, SCLX: Cyclically Adjusted PB Ratio Comparison

For the Drug Manufacturers - General subindustry, Biogen's Cyclically Adjusted PB Ratio, along with its competitors' market caps and Cyclically Adjusted PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Biogen Cyclically Adjusted PB Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Biogen's Cyclically Adjusted PB Ratio distribution charts can be found below:

* The bar in red indicates where Biogen's Cyclically Adjusted PB Ratio falls into.


XSWX:BIIB
74GF Score
Biogen Inc XSWX:BIIB
Cyclically Adjusted PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
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Biogen Cyclically Adjusted PB Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PB Ratio takes the Book Value per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/B calculation. Because it considers this 10-year average, it's often referred to as the CAPB Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PB Ratio.

Biogen's Cyclically Adjusted PB Ratio for today is calculated as

Cyclically Adjusted PB Ratio=Share Price/ Cyclically Adjusted Book per Share
=173.46/75.96
=2.28

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Biogen's Cyclically Adjusted Book per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Biogen's adjusted Book Value per Share data for the three months ended in Mar. 2026 was:

Adj_Book=Book Value per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=99.488/330.2130*330.2130
=99.488

Current CPI (Mar. 2026) = 330.2130.

Biogen Quarterly Data

Book Value per Share CPI Adj_Book
201606 50.456 241.018 69.129
201609 54.201 241.428 74.133
201612 57.295 241.432 78.364
201703 53.721 243.801 72.762
201706 53.046 244.955 71.509
201709 58.532 246.819 78.309
201712 58.860 246.524 78.842
201803 63.139 249.554 83.546
201806 60.257 251.989 78.962
201809 66.160 252.439 86.543
201812 65.588 251.233 86.207
201903 70.885 254.202 92.081
201906 69.250 256.143 89.275
201909 76.220 256.759 98.025
201912 75.264 256.974 96.715
202003 71.944 258.115 92.040
202006 67.959 257.797 87.049
202009 63.957 260.280 81.141
202012 62.376 260.474 79.076
202103 65.952 264.877 82.220
202106 65.463 271.696 79.562
202109 65.519 274.310 78.871
202112 68.268 278.802 80.857
202203 70.838 287.504 81.361
202206 79.330 296.311 88.406
202209 86.350 296.808 96.068
202212 86.677 296.797 96.436
202303 88.182 301.836 96.472
202306 89.959 305.109 97.361
202309 89.922 307.789 96.473
202312 88.327 306.746 95.084
202403 93.358 312.332 98.703
202406 98.146 314.175 103.156
202409 95.122 315.301 99.621
202412 102.279 315.605 107.013
202503 102.405 319.799 105.740
202506 97.817 322.561 100.137
202509 98.807 324.800 100.454
202512 99.107 324.054 100.991
202603 99.488 330.213 99.488

Add all the adjusted book value per share together and divide the count will get our Cyclically Adjusted Book per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PB Ratio of 2.28 mean?
Biogen (XSWX:BIIB) has a Cyclically Adjusted PB Ratio of 2.28 as of Jul. 25, 2026. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Biogen and its competitors. This is 53% below median its historical median of 4.81. Over the past decade, Biogen's Cyclically Adjusted PB Ratio has ranged from 1.31 to 9.94. According to the industry distribution chart, Biogen ranks #414 out of 756 companies in the Drug Manufacturers industry, placing it in the top 54.8%.
Is Biogen's Cyclically Adjusted PB Ratio too high?
Biogen's current Cyclically Adjusted PB Ratio of 2.28 is 53% below median its 10-year median of 4.81. Over the past 10 years, this metric has ranged from a low of 1.31 to a high of 9.94. The Drug Manufacturers industry median Cyclically Adjusted PB Ratio is 1.84. Biogen's value of 2.28 is 23.9% above this industry median. Based on the distribution chart, Biogen ranks #414 out of 756 companies in the Drug Manufacturers industry, which is below the industry midpoint. Overall, Biogen has a GF Score™ of 74/100, reflecting its overall financial health beyond just this single metric.
How does Biogen's Cyclically Adjusted PB Ratio compare to OGN and AMRN?
According to the Drug Manufacturers industry distribution chart, Biogen ranks #414 out of 756 companies for Cyclically Adjusted PB Ratio. This places Biogen in the lower half of its industry. The industry median Cyclically Adjusted PB Ratio is 1.84. Biogen's value of 2.28 is 23.9% above this benchmark. Historically, Biogen's own Cyclically Adjusted PB Ratio has ranged from 1.31 to 9.94 over the past decade. While the company's 10-year median is 4.81 vs. the industry median of 1.84, Biogen has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PB Ratio for a Drug Manufacturers company?
The median Cyclically Adjusted PB Ratio among Drug Manufacturers companies is 1.84, based on 756 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Biogen's current Cyclically Adjusted PB Ratio of 2.28 is 23.9% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PB Ratio mean?
A high Cyclically Adjusted PB Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PB Ratio is the ratio of share price to a company's inflation-adjusted book value per share over a 10-year period. View historical data on Biogen and its competitors. For the Drug Manufacturers industry, the median Cyclically Adjusted PB Ratio is 1.84 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Biogen's current Cyclically Adjusted PB Ratio is 2.28, which is 53% below median its own 10-year median of 4.81. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Biogen stock overvalued right now?
Biogen (XSWX:BIIB) has a current Cyclically Adjusted PB Ratio of 2.28. The stock's GF Value™ is CHF164.93, compared to a current price of CHF173.46 — trading 5.2% above its estimated fair value. The current Cyclically Adjusted PB Ratio is 2.28, which is 53% below median its 10-year median of 4.81 and 23.9% above the Drug Manufacturers industry median of 1.84. Biogen's overall GF Score™ is 74/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PB Ratio calculated?
Cyclically Adjusted PB Ratio is calculated from a company's financial statements. For Biogen (XSWX:BIIB), the current Cyclically Adjusted PB Ratio is 2.28 as of Jul. 25, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Biogen (XSWX:BIIB) Overvalued in 2026?

Based on GuruFocus' analysis, Biogen stock appears to be overvalued. The current stock price of CHF173.46 is trading 5.2% above its estimated GF Value™ of CHF164.93.

Key valuation signals for XSWX:BIIB:

  • Cyclically Adjusted PB Ratio: 2.28 (53% below median its 10-year median of 4.81)
  • GF Value™: CHF164.93 vs. price of CHF173.46 (5.2% above fair value)
  • GF Score™: 74/100 with 7 warning signs
  • Industry Position: 23.9% above the Drug Manufacturers median (#414 of 756)

No single metric tells the full story. See the XSWX:BIIB stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Biogen Business Description

Address 225 Binney Street, Cambridge, MA, USA, 02142
Biogen is an established biopharmaceutical company focused on treatments for neurodegenerative and rare diseases. Its declining multiple sclerosis franchise is its largest revenue generator and contributed 40% of total revenue in 2025. Biogen also generates significant revenue from its CD20 collaboration agreements with Roche (19% of total in 2025), which includes oncology drugs Rituxan and Gazyva and multiple sclerosis drug Ocrevus. Biogen's newer franchises include Spinraza (spinal muscular atrophy, with partner Ionis), Leqembi (Alzheimer's disease, collabroation revenue from its partner Eisai), Skyclarys (Friedreich's ataxia, Reata), Zurzuvae (postpartum depression, Sage), and Qalsody (amyotrophic lateral sclerosis, Ionis).
74GF Score

Get the complete analysis for XSWX:BIIB

Cyclically Adjusted PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

CHF173.46
Price
CHF164.93
GF Value