BIFRF (Biofrontera AG) Cyclically Adjusted PS Ratio: 0.27 (As of Aug. 18, 2026) — 75% Below Median

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BIFRF Biofrontera AG BIFRF
62 GF Score
Price $22.68
GF Value $22.02
! 4 Warning Signs
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What is Biofrontera AG Cyclically Adjusted PS Ratio?

Biofrontera AG BIFRF 62 Cyclically Adjusted PS Ratio is 0.27 as of Aug. 18, 2026, which is 75% below its 10-year median of 1.08. GuruFocus rates BIFRF with a GF Score™ of 62/100 and a GF Value™ of $22.02. The stock has 4 warning signs investors should review. Among 749 Drug Manufacturers companies, Biofrontera AG ranks better than 92.12% on this metric.

As of today (2026-08-18), Biofrontera AG's current share price is $22.68. Biofrontera AG's Cyclically Adjusted Revenue per Share for the quarter that ended in Mar. 2026 was $82.75. Biofrontera AG's Cyclically Adjusted PS Ratio for today is 0.27.

The historical rank and industry rank for Biofrontera AG's Cyclically Adjusted PS Ratio or its related term are showing as below:

BIFRF' s Cyclically Adjusted PS Ratio Range Over the Past 10 Years
Min: 0.23   Med: 1.08   Max: 8.77
Current: 0.26

During the past years, Biofrontera AG's highest Cyclically Adjusted PS Ratio was 8.77. The lowest was 0.23. And the median was 1.08.

BIFRF's Cyclically Adjusted PS Ratio is ranked better than
92.12% of 749 companies
in the Drug Manufacturers industry
Industry Median: 2.05 vs BIFRF: 0.26

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PS Ratio. The Cyclically Adjusted Revenue per Share is the average of the inflation adjusted revenue per share of a company over the past 10 years.

Biofrontera AG's adjusted revenue per share data for the three months ended in Mar. 2026 was $0.703. Add all the adjusted revenue per share for the past 10 years together and divide 10 will get our Cyclically Adjusted Revenue per Share, which is $82.75 for the trailing ten years ended in Mar. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Biofrontera AG  (OTCPK:BIFRF) Cyclically Adjusted PS Ratio Explanation

Compared with the regular PS Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PS Ratio smoothed out the fluctuations of revenue during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PS Ratio should give similar results to regular PS Ratio.


Biofrontera AG Cyclically Adjusted PS Ratio Related Terms


Biofrontera AG Cyclically Adjusted PS Ratio Historical Data

* Premium members only.

The historical data trend for Biofrontera AG's Cyclically Adjusted PS Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Biofrontera AG Cyclically Adjusted PS Ratio Chart

Biofrontera AG Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PS Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 4.07 3.94 0.92 0.23 0.26

Biofrontera AG Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Cyclically Adjusted PS Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.26 0.24 0.29 0.26 0.27

BIFRF vs ZTS, UTHR, VTRS: Cyclically Adjusted PS Ratio Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Biofrontera AG's Cyclically Adjusted PS Ratio, along with its competitors' market caps and Cyclically Adjusted PS Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Biofrontera AG Cyclically Adjusted PS Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Biofrontera AG's Cyclically Adjusted PS Ratio distribution charts can be found below:

* The bar in red indicates where Biofrontera AG's Cyclically Adjusted PS Ratio falls into.


BIFRF
62GF Score
Biofrontera AG BIFRF
Cyclically Adjusted PS Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
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Biofrontera AG Cyclically Adjusted PS Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PS Ratio takes the Revenue per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/S calculation. Because it considers this 10-year average, it's often referred to as the CAPS Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PS Ratio.

Biofrontera AG's Cyclically Adjusted PS Ratio for today is calculated as

Cyclically Adjusted PS Ratio=Share Price/ Cyclically Adjusted Revenue per Share
=22.68/82.75
=0.27

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Biofrontera AG's Cyclically Adjusted Revenue per Share for the quarter that ended in Mar. 2026 is calculated as:

For example, Biofrontera AG's adjusted Revenue per Share data for the three months ended in Mar. 2026 was:

Adj_RevenuePerShare=Revenue per Share/CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=0.703/131.2583*131.2583
=0.703

Current CPI (Mar. 2026) = 131.2583.

Biofrontera AG Quarterly Data

Revenue per Share CPI Adj_RevenuePerShare
201606 0.475 100.717 0.619
201609 0.808 101.017 1.050
201612 2.333 101.217 3.025
201703 1.450 101.417 1.877
201706 1.391 102.117 1.788
201709 1.346 102.717 1.720
201712 2.929 102.617 3.747
201803 2.845 102.917 3.628
201806 1.950 104.017 2.461
201809 2.858 104.718 3.582
201812 3.268 104.217 4.116
201903 3.424 104.217 4.312
201906 3.768 105.718 4.678
201909 2.476 106.018 3.065
201912 5.915 105.818 7.337
202003 3.658 105.718 4.542
202006 4.072 106.618 5.013
202009 2.421 105.818 3.003
202012 2.892 105.518 3.597
202103 2.419 107.518 2.953
202106 3.250 108.486 3.932
202109 2.242 109.435 2.689
202112 2.814 110.384 3.346
202203 2.585 113.968 2.977
202206 3.956 115.760 4.486
202209 2.505 118.818 2.767
202212 1.414 119.345 1.555
202303 2.044 122.402 2.192
202306 4.274 123.140 4.556
202309 2.464 124.195 2.604
202312 2.674 123.773 2.836
202403 1.329 125.038 1.395
202406 0.619 125.882 0.645
202409 0.629 126.198 0.654
202412 0.251 127.041 0.259
202503 0.574 127.779 0.590
202506 1.065 128.412 1.089
202509 0.676 129.255 0.686
202512 0.167 129.361 0.169
202603 0.703 131.258 0.703

Add all the adjusted revenue per share together and divide 10 will get our Cyclically Adjusted Revenue per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PS Ratio of 0.27 mean?
Biofrontera AG (BIFRF) has a Cyclically Adjusted PS Ratio of 0.27 as of Aug. 18, 2026. Cyclically Adjusted PS Ratio is the ratio of share price to a company's inflation-adjusted revenue per share over a 10-year period. View historical data on Biofrontera AG and its competitors. This is 75% below median its historical median of 1.08. Over the past decade, Biofrontera AG's Cyclically Adjusted PS Ratio has ranged from 0.23 to 8.77. According to the industry distribution chart, Biofrontera AG ranks #59 out of 749 companies in the Drug Manufacturers industry, placing it in the top 7.9%.
Is Biofrontera AG's Cyclically Adjusted PS Ratio too high?
Biofrontera AG's current Cyclically Adjusted PS Ratio of 0.27 is 75% below median its 10-year median of 1.08. Over the past 10 years, this metric has ranged from a low of 0.23 to a high of 8.77. The Drug Manufacturers industry median Cyclically Adjusted PS Ratio is 2.05. Biofrontera AG's value of 0.27 is 86.8% below this industry median. Based on the distribution chart, Biofrontera AG ranks #59 out of 749 companies in the Drug Manufacturers industry, which is in the top quartile — a strong position relative to peers. Overall, Biofrontera AG has a GF Score™ of 62/100, reflecting its overall financial health beyond just this single metric.
How does Biofrontera AG's Cyclically Adjusted PS Ratio compare to ZTS and UTHR?
According to the Drug Manufacturers industry distribution chart, Biofrontera AG ranks #59 out of 749 companies for Cyclically Adjusted PS Ratio. This places Biofrontera AG in the top 8% of its industry — outperforming the majority of peers. The industry median Cyclically Adjusted PS Ratio is 2.05. Biofrontera AG's value of 0.27 is 86.8% below this benchmark. Historically, Biofrontera AG's own Cyclically Adjusted PS Ratio has ranged from 0.23 to 8.77 over the past decade. While the company's 10-year median is 1.08 vs. the industry median of 2.05, Biofrontera AG has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PS Ratio for a Drug Manufacturers company?
The median Cyclically Adjusted PS Ratio among Drug Manufacturers companies is 2.05, based on 749 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PS Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PS Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Biofrontera AG's current Cyclically Adjusted PS Ratio of 0.27 is 86.8% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PS Ratio mean?
A high Cyclically Adjusted PS Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PS Ratio is the ratio of share price to a company's inflation-adjusted revenue per share over a 10-year period. View historical data on Biofrontera AG and its competitors. For the Drug Manufacturers industry, the median Cyclically Adjusted PS Ratio is 2.05 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Biofrontera AG's current Cyclically Adjusted PS Ratio is 0.27, which is 75% below median its own 10-year median of 1.08. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Biofrontera AG stock overvalued right now?
Biofrontera AG (BIFRF) has a current Cyclically Adjusted PS Ratio of 0.27. The stock's GF Value™ is $22.02, compared to a current price of $22.68 — trading 3% above its estimated fair value. The current Cyclically Adjusted PS Ratio is 0.27, which is 75% below median its 10-year median of 1.08 and 86.8% below the Drug Manufacturers industry median of 2.05. Biofrontera AG's overall GF Score™ is 62/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PS Ratio calculated?
Cyclically Adjusted PS Ratio is calculated from a company's financial statements. For Biofrontera AG (BIFRF), the current Cyclically Adjusted PS Ratio is 0.27 as of Aug. 18, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Biofrontera AG (BIFRF) Overvalued in 2026?

Based on GuruFocus' analysis, Biofrontera AG stock appears to be overvalued. The current stock price of $22.68 is trading 3% above its estimated GF Value™ of $22.02.

Key valuation signals for BIFRF:

  • Cyclically Adjusted PS Ratio: 0.27 (75% below median its 10-year median of 1.08)
  • GF Value™: $22.02 vs. price of $22.68 (3% above fair value)
  • GF Score™: 62/100 with 4 warning signs
  • Industry Position: 86.8% below the Drug Manufacturers median (#59 of 749)

No single metric tells the full story. See the BIFRF stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Biofrontera AG Business Description

Other Exchanges 0DOL:UKB8FK:Germany
Address Hemmelrather Weg 201, Leverkusen, NW, DEU, 51377
Biofrontera AG is active in the field of healthcare. It manufactures pharmaceutical products, especially medical cosmetics and dermatological drugs for the care and treatment of skin diseases. Its suite of products includes the prescription drugs Ameluz and BF-RhodoLED and BF-RhodoLED XL, for the treatment of actinic keratosis and Belixos, for the regenerative care of reddened and inflamed skin. Geographically, the company generates maximum revenue from Germany, and the rest from Spain, the United Kingdom, the rest of Europe, and other regions.
62GF Score

Get the complete analysis for BIFRF

Cyclically Adjusted PS Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$22.68
Price
$22.02
GF Value