CytomX Therapeutics (FRA:6C1) Cyclically Adjusted PS Ratio: 1.92 (As of Sep. 16, 2026) — Near Median

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FRA:6C1 CytomX Therapeutics Inc FRA:6C1
38 GF Score
Price €2.72
GF Value €0.12
Valuation Significantly Overvalued
! 6 Warning Signs
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What is CytomX Therapeutics Cyclically Adjusted PS Ratio?

CytomX Therapeutics FRA:6C1 -2.44% 38 Cyclically Adjusted PS Ratio is 1.92 as of Sep. 16, 2026, which is 9% above its 10-year median of 1.76. GuruFocus rates FRA:6C1 with a GF Score™ of 38/100 and a GF Value™ of €0.12 (Significantly Overvalued). The stock has 6 warning signs investors should review. Among 532 Biotechnology companies, CytomX Therapeutics ranks better than 69.74% on this metric.

As of today (2026-09-16), CytomX Therapeutics's current share price is €2.724. CytomX Therapeutics's Cyclically Adjusted Revenue per Share for the quarter that ended in Jun. 2026 was €1.42. CytomX Therapeutics's Cyclically Adjusted PS Ratio for today is 1.92.

The historical rank and industry rank for CytomX Therapeutics's Cyclically Adjusted PS Ratio or its related term are showing as below:

FRA:6C1' s Cyclically Adjusted PS Ratio Range Over the Past 10 Years
Min: 0.35   Med: 1.76   Max: 4.34
Current: 2.47

During the past years, CytomX Therapeutics's highest Cyclically Adjusted PS Ratio was 4.34. The lowest was 0.35. And the median was 1.76.

FRA:6C1's Cyclically Adjusted PS Ratio is ranked better than
69.74% of 532 companies
in the Biotechnology industry
Industry Median: 5.78 vs FRA:6C1: 2.47

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PS Ratio. The Cyclically Adjusted Revenue per Share is the average of the inflation adjusted revenue per share of a company over the past 10 years.

CytomX Therapeutics's adjusted revenue per share data for the three months ended in Jun. 2026 was €0.006. Add all the adjusted revenue per share for the past 10 years together and divide 10 will get our Cyclically Adjusted Revenue per Share, which is €1.42 for the trailing ten years ended in Jun. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


CytomX Therapeutics  (FRA:6C1) Cyclically Adjusted PS Ratio Explanation

Compared with the regular PS Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PS Ratio smoothed out the fluctuations of revenue during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PS Ratio should give similar results to regular PS Ratio.


CytomX Therapeutics Cyclically Adjusted PS Ratio Related Terms


CytomX Therapeutics Cyclically Adjusted PS Ratio Historical Data

* Premium members only.

The historical data trend for CytomX Therapeutics's Cyclically Adjusted PS Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

CytomX Therapeutics Cyclically Adjusted PS Ratio Chart

CytomX Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Cyclically Adjusted PS Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 1.47 1.20 0.77 2.71

CytomX Therapeutics Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted PS Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1.17 1.95 2.52 2.65 2.27

FRA:6C1 vs GYRE, BBOT, TECX: Cyclically Adjusted PS Ratio Comparison

For the Biotechnology subindustry, CytomX Therapeutics's Cyclically Adjusted PS Ratio, along with its competitors' market caps and Cyclically Adjusted PS Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


CytomX Therapeutics Cyclically Adjusted PS Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, CytomX Therapeutics's Cyclically Adjusted PS Ratio distribution charts can be found below:

* The bar in red indicates where CytomX Therapeutics's Cyclically Adjusted PS Ratio falls into.


FRA:6C1
38GF Score
CytomX Therapeutics Inc FRA:6C1
Cyclically Adjusted PS Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

CytomX Therapeutics Cyclically Adjusted PS Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PS Ratio takes the Revenue per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/S calculation. Because it considers this 10-year average, it's often referred to as the CAPS Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PS Ratio.

CytomX Therapeutics's Cyclically Adjusted PS Ratio for today is calculated as

Cyclically Adjusted PS Ratio=Share Price/ Cyclically Adjusted Revenue per Share
=2.724/1.416
=1.92

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

CytomX Therapeutics's Cyclically Adjusted Revenue per Share for the quarter that ended in Jun. 2026 is calculated as:

For example, CytomX Therapeutics's adjusted Revenue per Share data for the three months ended in Jun. 2026 was:

Adj_RevenuePerShare=Revenue per Share/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=0.006/333.9520*333.9520
=0.006

Current CPI (Jun. 2026) = 333.9520.

CytomX Therapeutics Quarterly Data

Revenue per Share CPI Adj_RevenuePerShare
201609 0.085 241.428 0.118
201612 0.159 241.432 0.220
201703 0.299 243.801 0.410
201706 0.216 244.955 0.294
201709 0.557 246.819 0.754
201712 0.598 246.524 0.810
201803 0.299 249.554 0.400
201806 0.460 251.989 0.610
201809 0.245 252.439 0.324
201812 0.223 251.233 0.296
201903 0.575 254.202 0.755
201906 0.177 256.143 0.231
201909 0.212 256.759 0.276
201912 0.165 256.974 0.214
202003 0.957 258.115 1.238
202006 0.327 257.797 0.424
202009 0.330 260.280 0.423
202012 0.296 260.474 0.379
202103 0.217 264.877 0.274
202106 0.208 271.696 0.256
202109 0.229 274.310 0.279
202112 0.264 278.802 0.316
202203 0.123 287.504 0.143
202206 0.260 296.311 0.293
202209 0.168 296.808 0.189
202212 0.298 296.797 0.335
202303 0.331 301.836 0.366
202306 0.341 305.109 0.373
202309 0.299 307.789 0.324
202312 0.368 306.746 0.401
202403 0.462 312.332 0.494
202406 0.275 314.175 0.292
202409 0.357 315.301 0.378
202412 0.446 315.605 0.472
202503 0.555 319.799 0.580
202506 0.128 322.561 0.133
202509 0.031 324.800 0.032
202512 0.003 324.054 0.003
202603 0.049 330.213 0.050
202606 0.006 333.952 0.006

Add all the adjusted revenue per share together and divide 10 will get our Cyclically Adjusted Revenue per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PS Ratio of 1.92 mean?
CytomX Therapeutics (FRA:6C1) has a Cyclically Adjusted PS Ratio of 1.92 as of Sep. 16, 2026. Cyclically Adjusted PS Ratio is the ratio of share price to a company's inflation-adjusted revenue per share over a 10-year period. View historical data on CytomX Therapeutics and its competitors. This is near median its historical median of 1.76. Over the past decade, CytomX Therapeutics' Cyclically Adjusted PS Ratio has ranged from 0.35 to 4.34. According to the industry distribution chart, CytomX Therapeutics ranks #161 out of 532 companies in the Biotechnology industry, placing it in the top 30.3%.
Is CytomX Therapeutics' Cyclically Adjusted PS Ratio too high?
CytomX Therapeutics' current Cyclically Adjusted PS Ratio of 1.92 is near median its 10-year median of 1.76. Over the past 10 years, this metric has ranged from a low of 0.35 to a high of 4.34. The Biotechnology industry median Cyclically Adjusted PS Ratio is 5.78. CytomX Therapeutics' value of 1.92 is 66.8% below this industry median. Based on the distribution chart, CytomX Therapeutics ranks #161 out of 532 companies in the Biotechnology industry, which is above the industry midpoint. Overall, CytomX Therapeutics has a GF Score™ of 38/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does CytomX Therapeutics' Cyclically Adjusted PS Ratio compare to GYRE and BBOT?
According to the Biotechnology industry distribution chart, CytomX Therapeutics ranks #161 out of 532 companies for Cyclically Adjusted PS Ratio. This puts CytomX Therapeutics in the upper half of its industry. The industry median Cyclically Adjusted PS Ratio is 5.78. CytomX Therapeutics' value of 1.92 is 66.8% below this benchmark. Historically, CytomX Therapeutics' own Cyclically Adjusted PS Ratio has ranged from 0.35 to 4.34 over the past decade. While the company's 10-year median is 1.76 vs. the industry median of 5.78, CytomX Therapeutics has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PS Ratio for a Biotechnology company?
The median Cyclically Adjusted PS Ratio among Biotechnology companies is 5.78, based on 532 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PS Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PS Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. CytomX Therapeutics's current Cyclically Adjusted PS Ratio of 1.92 is 66.8% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PS Ratio mean?
A high Cyclically Adjusted PS Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PS Ratio is the ratio of share price to a company's inflation-adjusted revenue per share over a 10-year period. View historical data on CytomX Therapeutics and its competitors. For the Biotechnology industry, the median Cyclically Adjusted PS Ratio is 5.78 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. CytomX Therapeutics's current Cyclically Adjusted PS Ratio is 1.92, which is near median its own 10-year median of 1.76. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is CytomX Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, CytomX Therapeutics (FRA:6C1) is currently considered Significantly Overvalued. The stock's GF Value™ is €0.12, compared to a current price of €2.72 — trading 2170% above its estimated fair value. The current Cyclically Adjusted PS Ratio is 1.92, which is near median its 10-year median of 1.76 and 66.8% below the Biotechnology industry median of 5.78. CytomX Therapeutics' overall GF Score™ is 38/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PS Ratio calculated?
Cyclically Adjusted PS Ratio is calculated from a company's financial statements. For CytomX Therapeutics (FRA:6C1), the current Cyclically Adjusted PS Ratio is 1.92 as of Sep. 16, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is CytomX Therapeutics (FRA:6C1) Overvalued in 2026?

Based on GuruFocus' analysis, CytomX Therapeutics stock appears to be overvalued. The current stock price of €2.72 is trading 2170% above its estimated GF Value™ of €0.12. GuruFocus considers CytomX Therapeutics to be Significantly Overvalued.

Key valuation signals for FRA:6C1:

  • Cyclically Adjusted PS Ratio: 1.92 (near median its 10-year median of 1.76)
  • GF Value™: €0.12 vs. price of €2.72 (2170% above fair value)
  • GF Score™: 38/100 with 6 warning signs
  • Industry Position: 66.8% below the Biotechnology median (#161 of 532)

No single metric tells the full story. See the FRA:6C1 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


CytomX Therapeutics Business Description

Other Exchanges CTMX:USA6C1:Germany
Address 151 Oyster Point Boulevard, Suite 400, South San Francisco, CA, USA, 94080
CytomX Therapeutics Inc a clinical-stage, oncology-focused biopharmaceutical company developing novel, masked, conditionally activated biologics designed to be localized to the tumor microenvironment. It is engaged in developing antibody therapeutics based on probody technology platforms. The company's probody technology platform creates proprietary cancer immunotherapies against clinically-validated targets and develops cancer therapeutics. Probody therapeutics are designed to take advantage of conditions in the tumor microenvironment to enhance the tumor-targeting features of an antibody and reduce drug activity in healthy tissues.
38GF Score

Get the complete analysis for FRA:6C1

Cyclically Adjusted PS Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€2.72
Price
€0.12
GF Value