Ono Pharmaceutical Co (FRA:ON4) Cyclically Adjusted PS Ratio: 2.84 (As of Aug. 02, 2026) — 53% Below Median

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FRA:ON4 Ono Pharmaceutical Co Ltd FRA:ON4
85 GF Score
Price €12.69
GF Value €11.59
Valuation Fairly Valued
! 3 Warning Signs
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What is Ono Pharmaceutical Co Cyclically Adjusted PS Ratio?

Ono Pharmaceutical Co FRA:ON4 -3.24% 85 Cyclically Adjusted PS Ratio is 2.84 as of Aug. 02, 2026, which is 53% below its 10-year median of 5.98. GuruFocus rates FRA:ON4 with a GF Score™ of 85/100 and a GF Value™ of €11.59 (Fairly Valued). The stock has 3 warning signs investors should review. Among 749 Drug Manufacturers companies, Ono Pharmaceutical Co ranks worse than 62.62% on this metric.

As of today (2026-08-02), Ono Pharmaceutical Co's current share price is €12.685. Ono Pharmaceutical Co's Cyclically Adjusted Revenue per Share for the quarter that ended in Jun. 2026 was €4.47. Ono Pharmaceutical Co's Cyclically Adjusted PS Ratio for today is 2.84.

The historical rank and industry rank for Ono Pharmaceutical Co's Cyclically Adjusted PS Ratio or its related term are showing as below:

FRA:ON4' s Cyclically Adjusted PS Ratio Range Over the Past 10 Years
Min: 2.05   Med: 5.98   Max: 10.51
Current: 2.85

During the past years, Ono Pharmaceutical Co's highest Cyclically Adjusted PS Ratio was 10.51. The lowest was 2.05. And the median was 5.98.

FRA:ON4's Cyclically Adjusted PS Ratio is ranked worse than
62.62% of 749 companies
in the Drug Manufacturers industry
Industry Median: 1.97 vs FRA:ON4: 2.85

The Shiller PE Ratio was first used by professor Robert Shiller. He uses E10 for his Shiller PE Ratio calculation. E10 is the average of the inflation adjusted earnings per share of a company over the past 10 years. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PS Ratio. The Cyclically Adjusted Revenue per Share is the average of the inflation adjusted revenue per share of a company over the past 10 years.

Ono Pharmaceutical Co's adjusted revenue per share data for the three months ended in Jun. 2026 was €1.334. Add all the adjusted revenue per share for the past 10 years together and divide 10 will get our Cyclically Adjusted Revenue per Share, which is €4.47 for the trailing ten years ended in Jun. 2026.

Shiller PE for Stocks: The True Measure of Stock Valuation


Ono Pharmaceutical Co  (FRA:ON4) Cyclically Adjusted PS Ratio Explanation

Compared with the regular PS Ratio, which works poorly for cyclical businesses, the Cyclically Adjusted PS Ratio smoothed out the fluctuations of revenue during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Cyclically Adjusted PS Ratio should give similar results to regular PS Ratio.


Ono Pharmaceutical Co Cyclically Adjusted PS Ratio Related Terms


Ono Pharmaceutical Co Cyclically Adjusted PS Ratio Historical Data

* Premium members only.

The historical data trend for Ono Pharmaceutical Co's Cyclically Adjusted PS Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ono Pharmaceutical Co Cyclically Adjusted PS Ratio Chart

Ono Pharmaceutical Co Annual Data
Trend Mar17 Mar18 Mar19 Mar20 Mar21 Mar22 Mar23 Mar24 Mar25 Mar26
Cyclically Adjusted PS Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 6.58 5.08 3.86 2.19 3.07

Ono Pharmaceutical Co Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Cyclically Adjusted PS Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 2.06 2.19 2.70 3.07 2.85

FRA:ON4 vs LLY, JNJ, ABBV: Cyclically Adjusted PS Ratio Comparison

For the Drug Manufacturers - General subindustry, Ono Pharmaceutical Co's Cyclically Adjusted PS Ratio, along with its competitors' market caps and Cyclically Adjusted PS Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Ono Pharmaceutical Co Cyclically Adjusted PS Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Ono Pharmaceutical Co's Cyclically Adjusted PS Ratio distribution charts can be found below:

* The bar in red indicates where Ono Pharmaceutical Co's Cyclically Adjusted PS Ratio falls into.


FRA:ON4
85GF Score
Ono Pharmaceutical Co Ltd FRA:ON4
Cyclically Adjusted PS Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Ono Pharmaceutical Co Cyclically Adjusted PS Ratio Calculation

Like the Shiller PE Ratio, the Cyclically Adjusted PS Ratio takes the Revenue per Share from the past 10 years, adjusts it for inflation, and then calculates the average. This average is then used for the P/S calculation. Because it considers this 10-year average, it's often referred to as the CAPS Ratio.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The similar calculation is applied by GuruFocus to calculate the Cyclically Adjusted PS Ratio.

Ono Pharmaceutical Co's Cyclically Adjusted PS Ratio for today is calculated as

Cyclically Adjusted PS Ratio=Share Price/ Cyclically Adjusted Revenue per Share
=12.685/4.47
=2.84

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ono Pharmaceutical Co's Cyclically Adjusted Revenue per Share for the quarter that ended in Jun. 2026 is calculated as:

For example, Ono Pharmaceutical Co's adjusted Revenue per Share data for the three months ended in Jun. 2026 was:

Adj_RevenuePerShare=Revenue per Share/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=1.334/113.6000*113.6000
=1.334

Current CPI (Jun. 2026) = 113.6000.

Ono Pharmaceutical Co Quarterly Data

Revenue per Share CPI Adj_RevenuePerShare
201609 0.974 98.000 1.129
201612 1.097 98.400 1.266
201703 0.874 98.100 1.012
201706 0.926 98.500 1.068
201709 0.888 98.800 1.021
201712 1.151 99.400 1.315
201803 0.910 99.200 1.042
201806 1.078 99.200 1.234
201809 1.088 99.900 1.237
201812 1.201 99.700 1.368
201903 1.013 99.700 1.154
201906 1.181 99.800 1.344
201909 1.258 100.100 1.428
201912 1.261 100.500 1.425
202003 1.129 100.300 1.279
202006 1.239 99.900 1.409
202009 1.217 99.900 1.384
202012 1.340 99.300 1.533
202103 1.151 99.900 1.309
202106 1.319 99.500 1.506
202109 1.340 100.100 1.521
202112 1.520 100.100 1.725
202203 1.405 101.100 1.579
202206 1.543 101.800 1.722
202209 1.588 103.100 1.750
202212 1.753 104.100 1.913
202303 1.547 104.400 1.683
202306 1.605 105.200 1.733
202309 1.816 106.200 1.943
202312 1.756 106.800 1.868
202403 1.465 107.200 1.552
202406 1.473 108.200 1.547
202409 1.646 108.900 1.717
202412 1.773 110.700 1.819
202503 1.483 111.100 1.516
202506 1.627 111.700 1.655
202509 1.589 112.000 1.612
202512 1.630 113.000 1.639
202603 1.377 112.700 1.388
202606 1.334 113.600 1.334

Add all the adjusted revenue per share together and divide 10 will get our Cyclically Adjusted Revenue per Share.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

What does a Cyclically Adjusted PS Ratio of 2.84 mean?
Ono Pharmaceutical Co (FRA:ON4) has a Cyclically Adjusted PS Ratio of 2.84 as of Aug. 02, 2026. Cyclically Adjusted PS Ratio is the ratio of share price to a company's inflation-adjusted revenue per share over a 10-year period. View historical data on Ono Pharmaceutical Co and its competitors. This is 53% below median its historical median of 5.98. Over the past decade, Ono Pharmaceutical Co's Cyclically Adjusted PS Ratio has ranged from 2.05 to 10.51. According to the industry distribution chart, Ono Pharmaceutical Co ranks #469 out of 749 companies in the Drug Manufacturers industry, placing it in the top 62.6%.
Is Ono Pharmaceutical Co's Cyclically Adjusted PS Ratio too high?
Ono Pharmaceutical Co's current Cyclically Adjusted PS Ratio of 2.84 is 53% below median its 10-year median of 5.98. Over the past 10 years, this metric has ranged from a low of 2.05 to a high of 10.51. The Drug Manufacturers industry median Cyclically Adjusted PS Ratio is 1.97. Ono Pharmaceutical Co's value of 2.84 is 44.2% above this industry median. Based on the distribution chart, Ono Pharmaceutical Co ranks #469 out of 749 companies in the Drug Manufacturers industry, which is below the industry midpoint. Overall, Ono Pharmaceutical Co has a GF Score™ of 85/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Ono Pharmaceutical Co's Cyclically Adjusted PS Ratio compare to LLY and JNJ?
According to the Drug Manufacturers industry distribution chart, Ono Pharmaceutical Co ranks #469 out of 749 companies for Cyclically Adjusted PS Ratio. This places Ono Pharmaceutical Co in the lower half of its industry. The industry median Cyclically Adjusted PS Ratio is 1.97. Ono Pharmaceutical Co's value of 2.84 is 44.2% above this benchmark. Historically, Ono Pharmaceutical Co's own Cyclically Adjusted PS Ratio has ranged from 2.05 to 10.51 over the past decade. While the company's 10-year median is 5.98 vs. the industry median of 1.97, Ono Pharmaceutical Co has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Cyclically Adjusted PS Ratio for a Drug Manufacturers company?
The median Cyclically Adjusted PS Ratio among Drug Manufacturers companies is 1.97, based on 749 companies in the industry. Companies in the top quartile (top 25%) have a Cyclically Adjusted PS Ratio significantly above this median, while those in the bottom quartile fall well below. However, Cyclically Adjusted PS Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Ono Pharmaceutical Co's current Cyclically Adjusted PS Ratio of 2.84 is 44.2% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Cyclically Adjusted PS Ratio mean?
A high Cyclically Adjusted PS Ratio can signal that a stock is expensive relative to its fundamentals. Cyclically Adjusted PS Ratio is the ratio of share price to a company's inflation-adjusted revenue per share over a 10-year period. View historical data on Ono Pharmaceutical Co and its competitors. For the Drug Manufacturers industry, the median Cyclically Adjusted PS Ratio is 1.97 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Ono Pharmaceutical Co's current Cyclically Adjusted PS Ratio is 2.84, which is 53% below median its own 10-year median of 5.98. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Ono Pharmaceutical Co stock overvalued right now?
Based on GuruFocus' analysis, Ono Pharmaceutical Co (FRA:ON4) is currently considered Fairly Valued. The stock's GF Value™ is €11.59, compared to a current price of €12.69 — trading 9.4% above its estimated fair value. The current Cyclically Adjusted PS Ratio is 2.84, which is 53% below median its 10-year median of 5.98 and 44.2% above the Drug Manufacturers industry median of 1.97. Ono Pharmaceutical Co's overall GF Score™ is 85/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Cyclically Adjusted PS Ratio calculated?
Cyclically Adjusted PS Ratio is calculated from a company's financial statements. For Ono Pharmaceutical Co (FRA:ON4), the current Cyclically Adjusted PS Ratio is 2.84 as of Aug. 02, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Ono Pharmaceutical Co (FRA:ON4) Overvalued in 2026?

Based on GuruFocus' analysis, Ono Pharmaceutical Co stock appears to be overvalued. The current stock price of €12.69 is trading 9.4% above its estimated GF Value™ of €11.59. GuruFocus considers Ono Pharmaceutical Co to be Fairly Valued.

Key valuation signals for FRA:ON4:

  • Cyclically Adjusted PS Ratio: 2.84 (53% below median its 10-year median of 5.98)
  • GF Value™: €11.59 vs. price of €12.69 (9.4% above fair value)
  • GF Score™: 85/100 with 3 warning signs
  • Industry Position: 44.2% above the Drug Manufacturers median (#469 of 749)

No single metric tells the full story. See the FRA:ON4 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Ono Pharmaceutical Co Business Description

Other Exchanges OPHLY:USA4528:Japan
Address 1-8-2 Kyutarocho, Chuo-ku, Osaka, JPN, 541-8564
Ono Pharmaceutical Co Ltd is a drug manufacturer with a focus on drug discovery in areas of unmet medical needs. The vast majority of the company's revenue is derived from its circulatory and respiratory drugs, followed by its metabolic drugs and vitamins. The company also reports revenue derived from royalties. The bulk of the company's sales is generated in Japan, followed by the rest of Asia and Europe.
85GF Score

Get the complete analysis for FRA:ON4

Cyclically Adjusted PS Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€12.69
Price
€11.59
GF Value