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Nippon Shinyaku CoTSE:4516 +1.13%77 Debt-to-EBITDA is 0.13 as of Mar. 2026, which is 86% above its 10-year median of 0.07. GuruFocus rates TSE:4516 with a GF Score™ of 77/100 and a GF Value™ of 円4,747.83 (Modestly Undervalued). The stock has 3 warning signs investors should review. Among 683 Drug Manufacturers companies, Nippon Shinyaku Co ranks better than 90.34% on this metric.
Debt-to-EBITDA measures a company's ability to pay off its debt.
A high Debt-to-EBITDA ratio generally means that a company may spend more time to paying off its debt. According to Joel Tillinghast's BIG MONEY THINKS SMALL: Biases, Blind Spots, and Smarter Investing, a ratio of Debt-to-EBITDA exceeding four is usually considered scary unless tangible assets cover the debt.
The historical rank and industry rank for Nippon Shinyaku Co's Debt-to-EBITDA or its related term are showing as below:
TSE:4516'
s Debt-to-EBITDA Range Over the Past 10 Years
Min: 0.06 Med: 0.07 Max: 0.09
Current: 0.06
During the past 13 years, the highest Debt-to-EBITDA Ratio of Nippon Shinyaku Co was 0.09. The lowest was 0.06. And the median was 0.07.
TSE:4516's Debt-to-EBITDA is ranked better than 90.34% of 683
companies
in the Drug Manufacturers industry
Industry Median: 1.63
vs TSE:4516: 0.06
A high Debt-to-EBITDA ratio generally means that a company may spend more time to paying off its debt.
According to Joel Tillinghast's BIG MONEY THINKS SMALL: Biases, Blind Spots, and Smarter Investing, a ratio of Debt-to-EBITDA exceeding four is usually considered scary unless tangible assets cover the debt.
Nippon Shinyaku Co Debt-to-EBITDA Related Terms
Nippon Shinyaku Co Debt-to-EBITDA Historical Data
* Premium members only.
The historical data trend for Nippon Shinyaku Co's Debt-to-EBITDA can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Drug Manufacturers - Specialty & Generic subindustry, Nippon Shinyaku Co's Debt-to-EBITDA, along with its competitors' market caps and Debt-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Nippon Shinyaku Co Debt-to-EBITDA vs Drug Manufacturers Industry
For the Drug Manufacturers industry and Healthcare sector, Nippon Shinyaku Co's Debt-to-EBITDA distribution charts can be found below:
* The bar in red indicates where Nippon Shinyaku Co's Debt-to-EBITDA falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
In the calculation of annual Debt-to-EBITDA, the EBITDA of the last fiscal year is used. In calculating the annualized quarterly data,
the EBITDA data used here is four times the quarterly (Mar. 2026) EBITDA data.
Nippon Shinyaku Co (TSE:4516) has a Debt-to-EBITDA of 0.13 as of Mar. 2026. Debt-to-EBITDA ratio represents the ratio of total debt to total earnings before interest, taxes, depreciation and amortization. View historical data on Nippon Shinyaku Co. This is 86% above median its historical median of 0.07. Over the past decade, Nippon Shinyaku Co's Debt-to-EBITDA has ranged from 0.06 to 0.09. According to the industry distribution chart, Nippon Shinyaku Co ranks #66 out of 683 companies in the Drug Manufacturers industry, placing it in the top 9.7%.
Is Nippon Shinyaku Co's Debt-to-EBITDA too high?
Nippon Shinyaku Co's current Debt-to-EBITDA of 0.13 is 86% above median its 10-year median of 0.07. Over the past 10 years, this metric has ranged from a low of 0.06 to a high of 0.09. The Drug Manufacturers industry median Debt-to-EBITDA is 1.63. Nippon Shinyaku Co's value of 0.13 is 92% below this industry median. Based on the distribution chart, Nippon Shinyaku Co ranks #66 out of 683 companies in the Drug Manufacturers industry, which is in the top quartile — a strong position relative to peers. Overall, Nippon Shinyaku Co has a GF Score™ of 77/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Nippon Shinyaku Co's Debt-to-EBITDA compare to ZTS?
According to the Drug Manufacturers industry distribution chart, Nippon Shinyaku Co ranks #66 out of 683 companies for Debt-to-EBITDA. This places Nippon Shinyaku Co in the top 10% of its industry — outperforming the majority of peers. The industry median Debt-to-EBITDA is 1.63. Nippon Shinyaku Co's value of 0.13 is 92% below this benchmark. Historically, Nippon Shinyaku Co's own Debt-to-EBITDA has ranged from 0.06 to 0.09 over the past decade. While the company's 10-year median is 0.07 vs. the industry median of 1.63, Nippon Shinyaku Co has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Debt-to-EBITDA for a Drug Manufacturers company?
The median Debt-to-EBITDA among Drug Manufacturers companies is 1.63, based on 683 companies in the industry. Companies in the top quartile (top 25%) have a Debt-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, Debt-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Nippon Shinyaku Co's current Debt-to-EBITDA of 0.13 is 92% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Debt-to-EBITDA mean?
A high Debt-to-EBITDA can signal that a stock is expensive relative to its fundamentals. Debt-to-EBITDA ratio represents the ratio of total debt to total earnings before interest, taxes, depreciation and amortization. View historical data on Nippon Shinyaku Co. For the Drug Manufacturers industry, the median Debt-to-EBITDA is 1.63 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Nippon Shinyaku Co's current Debt-to-EBITDA is 0.13, which is 86% above median its own 10-year median of 0.07. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Nippon Shinyaku Co stock overvalued right now?
Based on GuruFocus' analysis, Nippon Shinyaku Co (TSE:4516) is currently considered Modestly Undervalued. The stock's GF Value™ is 円4,747.83, compared to a current price of 円3,579.00 — trading 24.6% below its estimated fair value. The current Debt-to-EBITDA is 0.13, which is 86% above median its 10-year median of 0.07 and 92% below the Drug Manufacturers industry median of 1.63. Nippon Shinyaku Co's overall GF Score™ is 77/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Debt-to-EBITDA calculated?
Debt-to-EBITDA is calculated from a company's financial statements. For Nippon Shinyaku Co (TSE:4516), the current Debt-to-EBITDA is 0.13 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Nippon Shinyaku Co (TSE:4516) Overvalued in 2026?
Based on GuruFocus' analysis, Nippon Shinyaku Co stock appears to be undervalued.
The current stock price of 円3,579.00 is trading 24.6% below its estimated GF Value™ of 円4,747.83.
GuruFocus considers Nippon Shinyaku Co to be Modestly Undervalued.
Key valuation signals for TSE:4516:
Debt-to-EBITDA: 0.13 (86% above median its 10-year median of 0.07)
GF Value™: 円4,747.83 vs. price of 円3,579.00 (24.6% below fair value)
Industry Position: 92% below the Drug Manufacturers median (#66 of 683)
No single metric tells the full story. See the TSE:4516 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Nippon Shinyaku Co Ltd is engaged in the pharmaceuticals and functional food businesses. The Pharmaceuticals Business develops and sells treatments for urological disorders, blood cancer, rare and intractable diseases, and gynecological conditions. The Functional Food Business produces and sells health food ingredients, quality-stabilizing preservatives, protein preparations, and supplements. It generates the majority of its revenue from the Pharmaceuticals segment.
77GF Score
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