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A high debt to equity ratio generally means that a company has been aggressive in financing its growth with debt. This can result in volatile earnings as a result of the additional interest expense.
The historical rank and industry rank for PTC Therapeutics's Debt-to-Equity or its related term are showing as below:
PTCT'
s Debt-to-Equity Range Over the Past 10 Years
Min: -13.19 Med: 0.36 Max: 882.73
Current: -4.21
During the past 13 years, the highest Debt-to-Equity Ratio of PTC Therapeutics was 882.73. The lowest was -13.19. And the median was 0.36.
PTCT's Debt-to-Equity is not ranked
in the Biotechnology industry.
Industry Median: 0.16
vs PTCT: -4.21
Because a company can increase its ROE % by having more financial leverage, it is important to watch the leverage ratio when investing in high ROE % companies.
PTC Therapeutics Debt-to-Equity Related Terms
PTC Therapeutics Debt-to-Equity Historical Data
* Premium members only.
The historical data trend for PTC Therapeutics's Debt-to-Equity can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
PTCT vs XENE, CGON, ERAS: Debt-to-Equity Comparison
For the Biotechnology subindustry, PTC Therapeutics's Debt-to-Equity, along with its competitors' market caps and Debt-to-Equity data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
PTC Therapeutics Debt-to-Equity vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, PTC Therapeutics's Debt-to-Equity distribution charts can be found below:
* The bar in red indicates where PTC Therapeutics's Debt-to-Equity falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
PTC Therapeutics (PTCT) has a Debt-to-Equity of -4.21 as of Jun. 2026. Debt-to-Equity ratio represents the ratio of total debt to total company equity. View historical data on PTC Therapeutics and its competitors. According to the industry distribution chart, PTC Therapeutics ranks #999999 out of 967 companies in the Biotechnology industry.
Is PTC Therapeutics' Debt-to-Equity too high?
PTC Therapeutics' current Debt-to-Equity is -4.21. Based on the distribution chart, PTC Therapeutics ranks #999999 out of 967 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, PTC Therapeutics has a GF Score™ of 62/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does PTC Therapeutics' Debt-to-Equity compare to XENE and CGON?
According to the Biotechnology industry distribution chart, PTC Therapeutics ranks #999999 out of 967 companies for Debt-to-Equity. This places PTC Therapeutics in the lower half of its industry. The industry median Debt-to-Equity is 0.16. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Debt-to-Equity for a Biotechnology company?
The median Debt-to-Equity among Biotechnology companies is 0.16, based on 967 companies in the industry. Companies in the top quartile (top 25%) have a Debt-to-Equity significantly above this median, while those in the bottom quartile fall well below. However, Debt-to-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Debt-to-Equity mean?
A high Debt-to-Equity can signal that a stock is expensive relative to its fundamentals. Debt-to-Equity ratio represents the ratio of total debt to total company equity. View historical data on PTC Therapeutics and its competitors. For the Biotechnology industry, the median Debt-to-Equity is 0.16 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. PTC Therapeutics's current Debt-to-Equity is -4.21. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is PTC Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, PTC Therapeutics (PTCT) is currently considered Significantly Overvalued. The stock's GF Value™ is $37.54, compared to a current price of $72.64 — trading 93.5% above its estimated fair value. The current Debt-to-Equity is -4.21. PTC Therapeutics' overall GF Score™ is 62/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Debt-to-Equity calculated?
Debt-to-Equity is calculated from a company's financial statements. For PTC Therapeutics (PTCT), the current Debt-to-Equity is -4.21 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is PTC Therapeutics (PTCT) Overvalued in 2026?
Based on GuruFocus' analysis, PTC Therapeutics stock appears to be overvalued.
The current stock price of $72.64 is trading 93.5% above its estimated GF Value™ of $37.54.
GuruFocus considers PTC Therapeutics to be Significantly Overvalued.
Key valuation signals for PTCT:
Debt-to-Equity: -4.21
GF Value™: $37.54 vs. price of $72.64 (93.5% above fair value)
No single metric tells the full story. See the PTCT stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
PTC Therapeutics Inc is a biopharmaceutical company that discovers, develops and commercializes clinically differentiated medicines that provide benefits to children and adults living with rare disorders. Its diversified therapeutic portfolio that includes several commercial products and product candidates in various stages of development, including discovery, research and clinical stages, focused on the development of new treatments for multiple therapeutic areas for rare diseases relating to neurology and metabolism. The company views its operations and manages its business in one operating segment: life science, which is focused on the discovery, development and commercialization of the company's clinically differentiated medicines that provide benefits to patients with rare disorders.
62GF Score
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