Tissue Regenix Group (FRA:LSW) Degree of Operating Leverage : -52.69 (As of Dec. 2025)

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FRA:LSW Tissue Regenix Group PLC FRA:LSW
10 GF Score
Price €0.07
GF Value €0.84
! 7 Warning Signs
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What is Tissue Regenix Group Degree of Operating Leverage?

Tissue Regenix Group FRA:LSW 10 Degree of Operating Leverage is -52.69 as of Dec. 2025. GuruFocus rates FRA:LSW with a GF Score™ of 10/100 and a GF Value™ of €0.84. The stock has 7 warning signs investors should review.

Degree of Operating Leverage (DOL) measures the percentage change in EBIT for a unit change in Revenue. Tissue Regenix Group's Degree of Operating Leverage for the quarter that ended in Dec. 2025 was -52.69. The higher Degree of Operating Leverage, the higher operating risk the company will take.

The industry rank for Tissue Regenix Group's Degree of Operating Leverage or its related term are showing as below:

FRA:LSW's Degree of Operating Leverage is not ranked
in the Biotechnology industry.
Industry Median: 0.01 vs FRA:LSW: -52.69

Tissue Regenix Group  (FRA:LSW) Degree of Operating Leverage Explanation

Degree of Operating Leverage (DOL) is a leverage ratio that measures the sensitivity of a company’s operting income, also referred to as Earnings Before Interest and Taxes (EBIT), to fluctuations in its Revenue. DOL is a method used to quantify a company’s operating risk. This risk is related to the company's structure of variable costs and fixed costs. Since the fixed costs do not allow the company to adjust the operating costs, the operating risk rises with a higher fixed-to-variable costs proportion.

A high Degree of Operating Leverage indicates that the company’s fixed costs exceed its variable costs. By increasing the sales, the company can earn more profits. In addition, the company must be able to maintain relatively high sales to cover all fixed costs.

Be Aware

The use of operating leverage varies across different industries and business sectors, and the application of Degree of Operating Leverage (DOL) should be adjusted accordingly.


Tissue Regenix Group Degree of Operating Leverage Related Terms


Tissue Regenix Group Degree of Operating Leverage Historical Data

* Premium members only.

The historical data trend for Tissue Regenix Group's Degree of Operating Leverage can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Tissue Regenix Group Degree of Operating Leverage Chart

Tissue Regenix Group Annual Data
Trend Jan16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Degree of Operating Leverage
Get a 7-Day Free Trial Premium Member Only Premium Member Only -2.13 -1.55 -12.04 2.77 -52.69

Tissue Regenix Group Semi-Annual Data
Jan16 Jul16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
Degree of Operating Leverage Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -12.04 156.55 2.77 3.46 -52.69

FRA:LSW vs VRTX, REGN, ALNY: Degree of Operating Leverage Comparison

For the Biotechnology subindustry, Tissue Regenix Group's Degree of Operating Leverage, along with its competitors' market caps and Degree of Operating Leverage data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Tissue Regenix Group Degree of Operating Leverage vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Tissue Regenix Group's Degree of Operating Leverage distribution charts can be found below:

* The bar in red indicates where Tissue Regenix Group's Degree of Operating Leverage falls into.


FRA:LSW
10GF Score
Tissue Regenix Group PLC FRA:LSW
Degree of Operating Leverage is just one metric. See GF Score™, valuation, warning signs, and more.
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Tissue Regenix Group Degree of Operating Leverage Calculation

Tissue Regenix Group's Degree of Operating Leverage for the quarter that ended in Dec. 2025 is calculated as:

Degree of Operating Leverage=% Change in EBIT**/% Change in Revenue
=( -8.695 (Dec. 2025) / -1.255 (Dec. 2024) - 1 )/( 24.279 (Dec. 2025) / 27.357 (Dec. 2024) - 1 )
=5.9283/-0.1125
=-52.69***

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

** TTM data of EBIT and Revenue was used to calculate Degree of Operating Leverage.
*** Please be aware that the Degree of Operating Leverage calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.

What does a Degree of Operating Leverage of -52.69 mean?
Tissue Regenix Group (FRA:LSW) has a Degree of Operating Leverage of -52.69 as of Dec. 2025. Degree of Operating Leverage (DOL) measures the percentage change in EBIT for a unit change in Revenue. View historical data for Tissue Regenix Group and its competitors.
Is Tissue Regenix Group's Degree of Operating Leverage too high?
Tissue Regenix Group's current Degree of Operating Leverage is -52.69. Overall, Tissue Regenix Group has a GF Score™ of 10/100, reflecting its overall financial health beyond just this single metric.
How does Tissue Regenix Group's Degree of Operating Leverage compare to VRTX and REGN?
Tissue Regenix Group's Degree of Operating Leverage of -52.69 can be compared against companies in the Biotechnology industry. The industry median Degree of Operating Leverage is 0.01. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Degree of Operating Leverage for a Biotechnology company?
The median Degree of Operating Leverage among Biotechnology companies is 0.01, based on 859 companies in the industry. Companies in the top quartile (top 25%) have a Degree of Operating Leverage significantly above this median, while those in the bottom quartile fall well below. However, Degree of Operating Leverage should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Degree of Operating Leverage mean?
A high Degree of Operating Leverage can signal that a stock is expensive relative to its fundamentals. Degree of Operating Leverage (DOL) measures the percentage change in EBIT for a unit change in Revenue. View historical data for Tissue Regenix Group and its competitors. For the Biotechnology industry, the median Degree of Operating Leverage is 0.01 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Tissue Regenix Group's current Degree of Operating Leverage is -52.69. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Tissue Regenix Group stock overvalued right now?
Tissue Regenix Group (FRA:LSW) has a current Degree of Operating Leverage of -52.69. The stock's GF Value™ is €0.84, compared to a current price of €0.07 — trading 91.7% below its estimated fair value. The current Degree of Operating Leverage is -52.69. Tissue Regenix Group's overall GF Score™ is 10/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Degree of Operating Leverage calculated?
Degree of Operating Leverage is calculated from a company's financial statements. For Tissue Regenix Group (FRA:LSW), the current Degree of Operating Leverage is -52.69 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Tissue Regenix Group (FRA:LSW) Overvalued in 2026?

Based on GuruFocus' analysis, Tissue Regenix Group stock appears to be undervalued. The current stock price of €0.07 is trading 91.7% below its estimated GF Value™ of €0.84.

Key valuation signals for FRA:LSW:

  • Degree of Operating Leverage: -52.69
  • GF Value™: €0.84 vs. price of €0.07 (91.7% below fair value)
  • GF Score™: 10/100 with 7 warning signs

No single metric tells the full story. See the FRA:LSW stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Tissue Regenix Group Business Description

Address Lotherton Way, Unit 3, Phoenix Court, Garforth, GBR, LS25 2GY
Tissue Regenix Group PLC is a pioneering medical technology company engaged in the development of regenerative products. The company incorporates dCELL and BioRinse technology, which helps to address complex and varying clinical needs. Its product portfolio includes Biosurgery, Orthopaedics, and Dental. The company has operations around the world, with special emphasis in the United States.
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Degree of Operating Leverage is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€0.07
Price
€0.84
GF Value