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Degree of Operating Leverage (DOL) measures the percentage change in EBIT for a unit change in Revenue.
Proteomics International Laboratories's Degree of Operating Leverage for the quarter that ended in Dec. 2025 was -17.97. The higher Degree of Operating Leverage, the higher operating risk the company will take.
PIQLF's Degree of Operating Leverage is ranked better than 94.13% of 852
companies
in the Biotechnology industry
Industry Median: -0.035
vs PIQLF: -17.97
Proteomics International Laboratories (OTCPK:PIQLF) Degree of Operating Leverage Explanation
Degree of Operating Leverage (DOL) is a leverage ratio that measures the sensitivity of a company’s operting income, also referred to as Earnings Before Interest and Taxes (EBIT), to fluctuations in its Revenue. DOL is a method used to quantify a company’s operating risk. This risk is related to the company's structure of variable costs and fixed costs. Since the fixed costs do not allow the company to adjust the operating costs, the operating risk rises with a higher fixed-to-variable costs proportion.
A high Degree of Operating Leverage indicates that the company’s fixed costs exceed its variable costs. By increasing the sales, the company can earn more profits. In addition, the company must be able to maintain relatively high sales to cover all fixed costs.
Be Aware
The use of operating leverage varies across different industries and business sectors, and the application of Degree of Operating Leverage (DOL) should be adjusted accordingly.
Proteomics International Laboratories Degree of Operating Leverage Related Terms
Proteomics International Laboratories Degree of Operating Leverage Historical Data
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Proteomics International Laboratories Degree of Operating Leverage Chart
PIQLF vs VRTX, REGN, RVMD: Degree of Operating Leverage Comparison
For the Biotechnology subindustry, Proteomics International Laboratories's Degree of Operating Leverage, along with its competitors' market caps and Degree of Operating Leverage data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Proteomics International Laboratories Degree of Operating Leverage vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Proteomics International Laboratories's Degree of Operating Leverage distribution charts can be found below:
* The bar in red indicates where Proteomics International Laboratories's Degree of Operating Leverage falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
** TTM data of EBIT and Revenue was used to calculate Degree of Operating Leverage.
*** Please be aware that the Degree of Operating Leverage calculations are based on company-level data using the primary share class. The calculated data provided is for demonstration purposes and may slightly differ from the results displayed in the title due to potential variations caused by currency exchange rate differences throughout the year.
What does a Degree of Operating Leverage of -17.97 mean?
Proteomics International Laboratories (PIQLF) has a Degree of Operating Leverage of -17.97 as of Dec. 2025. Degree of Operating Leverage (DOL) measures the percentage change in EBIT for a unit change in Revenue. View historical data for Proteomics International Laboratories and its competitors. According to the industry distribution chart, Proteomics International Laboratories ranks #50 out of 852 companies in the Biotechnology industry, placing it in the top 5.9%.
Is Proteomics International Laboratories' Degree of Operating Leverage too high?
Proteomics International Laboratories' current Degree of Operating Leverage is -17.97. Based on the distribution chart, Proteomics International Laboratories ranks #50 out of 852 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Proteomics International Laboratories has a GF Score™ of 26/100, reflecting its overall financial health beyond just this single metric.
How does Proteomics International Laboratories' Degree of Operating Leverage compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Proteomics International Laboratories ranks #50 out of 852 companies for Degree of Operating Leverage. This places Proteomics International Laboratories in the top 6% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Degree of Operating Leverage for a Biotechnology company?
A good Degree of Operating Leverage depends on the Biotechnology industry context. However, Degree of Operating Leverage should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Degree of Operating Leverage mean?
A high Degree of Operating Leverage can signal that a stock is expensive relative to its fundamentals. Degree of Operating Leverage (DOL) measures the percentage change in EBIT for a unit change in Revenue. View historical data for Proteomics International Laboratories and its competitors. Proteomics International Laboratories's current Degree of Operating Leverage is -17.97. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Proteomics International Laboratories stock overvalued right now?
Proteomics International Laboratories (PIQLF) has a current Degree of Operating Leverage of -17.97. The stock's GF Value™ is $0.83, compared to a current price of $0.26 — trading 68.7% below its estimated fair value. The current Degree of Operating Leverage is -17.97. Proteomics International Laboratories' overall GF Score™ is 26/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Degree of Operating Leverage calculated?
Degree of Operating Leverage is calculated from a company's financial statements. For Proteomics International Laboratories (PIQLF), the current Degree of Operating Leverage is -17.97 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Proteomics International Laboratories (PIQLF) Overvalued in 2026?
Based on GuruFocus' analysis, Proteomics International Laboratories stock appears to be undervalued.
The current stock price of $0.26 is trading 68.7% below its estimated GF Value™ of $0.83.
Key valuation signals for PIQLF:
Degree of Operating Leverage: -17.97
GF Value™: $0.83 vs. price of $0.26 (68.7% below fair value)
No single metric tells the full story. See the PIQLF stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Proteomics International Laboratories Business Description
Proteomics International Laboratories Ltd is a biological research and drug discovery company. It is a pioneering medical technology company operating at the forefront of predictive diagnostics and precision medicine. The Company specialises in proteomics-the industrial-scale study of the structure and function of proteins. Its pipeline includes Promarker, Pipeline PromarkerD, PromarkerEndo, PromarkerEso, and OxiDx.
26GF Score
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Degree of Operating Leverage is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
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