ARDX (Ardelyx) E10: $-1.35 (As of Jun. 2026)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

ARDX Ardelyx Inc ARDX
66 GF Score
Price $4.06
GF Value $8.71
Valuation Possible Value Trap
! 5 Warning Signs
View Full Analysis

What is Ardelyx E10?

Ardelyx ARDX +4.10% 66 E10 is $-1.35 as of Jun. 2026. GuruFocus rates ARDX with a GF Score™ of 66/100 and a GF Value™ of $8.71 (Possible Value Trap). The stock has 5 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Ardelyx's adjusted earnings per share data for the three months ended in Jun. 2026 was $-0.070. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is $-1.35 for the trailing ten years ended in Jun. 2026.

Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

As of today (2026-08-16), Ardelyx's current stock price is $4.06. Ardelyx's E10 for the quarter that ended in Jun. 2026 was $-1.35. Ardelyx's Shiller PE Ratio of today is .


Ardelyx  (NAS:ARDX) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Ardelyx E10 Related Terms


Ardelyx E10 Historical Data

* Premium members only.

The historical data trend for Ardelyx's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ardelyx E10 Chart

Ardelyx Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 -1.44 -1.45 -1.52 0.00

Ardelyx Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -1.61 0.00 0.00 -1.45 -1.35

ARDX vs IMTX, TRAX, AVLN: E10 Comparison

For the Biotechnology subindustry, Ardelyx's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Ardelyx Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Ardelyx's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Ardelyx's Shiller PE Ratio falls into.


ARDX
66GF Score
Ardelyx Inc ARDX
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Ardelyx E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Ardelyx's adjusted earnings per share data for the three months ended in Jun. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=-0.07/333.9520*333.9520
=-0.070

Current CPI (Jun. 2026) = 333.9520.

Ardelyx Quarterly Data

per share eps CPI Adj_EPS
201609 -0.650 241.428 -0.899
201612 -0.650 241.432 -0.899
201703 -0.590 243.801 -0.808
201706 -0.540 244.955 -0.736
201709 -0.440 246.819 -0.595
201712 0.210 246.524 0.284
201803 -0.360 249.554 -0.482
201806 -0.420 251.989 -0.557
201809 -0.390 252.439 -0.516
201812 -0.450 251.233 -0.598
201903 -0.420 254.202 -0.552
201906 -0.410 256.143 -0.535
201909 -0.370 256.759 -0.481
201912 -0.270 256.974 -0.351
202003 -0.250 258.115 -0.323
202006 -0.280 257.797 -0.363
202009 -0.200 260.280 -0.257
202012 -0.320 260.474 -0.410
202103 -0.340 264.877 -0.429
202106 -0.450 271.696 -0.553
202109 -0.420 274.310 -0.511
202112 -0.310 278.802 -0.371
202203 -0.210 287.504 -0.244
202206 -0.190 296.311 -0.214
202209 -0.140 296.808 -0.158
202212 0.060 296.797 0.068
202303 -0.130 301.836 -0.144
202306 -0.080 305.109 -0.088
202309 0.030 307.789 0.033
202312 -0.130 306.746 -0.142
202403 -0.110 312.332 -0.118
202406 -0.070 314.175 -0.074
202409 0.000 315.301 0.000
202412 0.020 315.605 0.021
202503 -0.170 319.799 -0.178
202506 -0.080 322.561 -0.083
202509 0.000 324.800 0.000
202512 0.000 324.054 0.000
202603 -0.150 330.213 -0.152
202606 -0.070 333.952 -0.070

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of $-1.35 mean?
Ardelyx (ARDX) has a E10 of $-1.35 as of Jun. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Ardelyx and its competitors.
Is Ardelyx's E10 too high?
Ardelyx's current E10 is $-1.35. Overall, Ardelyx has a GF Score™ of 66/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Ardelyx's E10 compare to IMTX and TRAX?
Ardelyx's E10 of $-1.35 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Ardelyx and its competitors. Ardelyx's current E10 is $-1.35. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Ardelyx stock overvalued right now?
Based on GuruFocus' analysis, Ardelyx (ARDX) is currently considered Possible Value Trap. The stock's GF Value™ is $8.71, compared to a current price of $4.06 — trading 53.4% below its estimated fair value. The current E10 is $-1.35. Ardelyx's overall GF Score™ is 66/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Ardelyx (ARDX), the current E10 is $-1.35 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Ardelyx (ARDX) Overvalued in 2026?

Based on GuruFocus' analysis, Ardelyx stock appears to be undervalued. The current stock price of $4.06 is trading 53.4% below its estimated GF Value™ of $8.71. GuruFocus considers Ardelyx to be Possible Value Trap.

Key valuation signals for ARDX:

  • E10: $-1.35
  • GF Value™: $8.71 vs. price of $4.06 (53.4% below fair value)
  • GF Score™: 66/100 with 5 warning signs

No single metric tells the full story. See the ARDX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Ardelyx Business Description

Other Exchanges ARDX:Mexico41X:Germany
Address 400 Fifth Avenue, Suite 210, Waltham, MA, USA, 02451
Ardelyx Inc is a biopharmaceutical company developing and commercialize, first-in-class medicines that meet unmet medical needs. It has developed a platform that enabled the discovery of new biological mechanisms and pathways to develop potent and efficacious therapies that minimize the side effects and drug-drug interactions frequently encountered with traditional, systemically absorbed medicines. Its products Tenapanor, branded as IBSRELA, is used for the treatment of adults with IBS-C. Tenapanor, branded as XPHOZAH, is used to reduce serum phosphorus in adults with CKD on dialysis as add-on therapy in patients who have an inadequate response to phosphate binders or who are intolerant of any dose of phosphate binder therapy.
66GF Score

Get the complete analysis for ARDX

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$4.06
Price
$8.71
GF Value