AstraZeneca (BUE:AZN) E10: ARS1,286.28 (As of Mar. 2026)

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BUE:AZN AstraZeneca PLC BUE:AZN
79 GF Score
Price ARS66,700.00
GF Value ARS71,271.93
Valuation Fairly Valued
! 1 Warning Sign
View Full Analysis

What is AstraZeneca E10?

AstraZeneca BUE:AZN +0.72% 79 E10 is ARS1,286.28 as of Mar. 2026. GuruFocus rates BUE:AZN with a GF Score™ of 79/100 and a GF Value™ of ARS71,271.93 (Fairly Valued). The stock has 1 warning sign investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

AstraZeneca's adjusted earnings per share data for the three months ended in Mar. 2026 was ARS2,754.543. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is ARS1,286.28 for the trailing ten years ended in Mar. 2026.

During the past 12 months, AstraZeneca's average E10 Growth Rate was 16.10% per year. During the past 3 years, the average E10 Growth Rate was 16.40% per year. During the past 5 years, the average E10 Growth Rate was 5.20% per year. During the past 10 years, the average E10 Growth Rate was -3.50% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of AstraZeneca was 77.50% per year. The lowest was -26.20% per year. And the median was 1.90% per year.

As of today (2026-07-22), AstraZeneca's current stock price is ARS66700.00. AstraZeneca's E10 for the quarter that ended in Mar. 2026 was ARS1,286.28. AstraZeneca's Shiller PE Ratio of today is 51.85.

During the past 13 years, the highest Shiller PE Ratio of AstraZeneca was 75.22. The lowest was 15.48. And the median was 42.54.


AstraZeneca  (BUE:AZN) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.

AstraZeneca's Shiller P/E Ratio of today is calculated as

Shiller PE Ratio=Share Price/E10
=66700.00/1286.28
=51.85

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Shiller P/E Ratio of AstraZeneca was 75.22. The lowest was 15.48. And the median was 42.54.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


AstraZeneca E10 Related Terms


AstraZeneca E10 Historical Data

* Premium members only.

The historical data trend for AstraZeneca's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

AstraZeneca E10 Chart

AstraZeneca Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 4.08 3.02 3.60 788.82 1,273.89

AstraZeneca Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 961.86 979.82 1,280.66 1,273.89 1,286.28

BUE:AZN vs LLY, JNJ, ABBV: E10 Comparison

For the Drug Manufacturers - General subindustry, AstraZeneca's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


AstraZeneca Shiller PE Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, AstraZeneca's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where AstraZeneca's Shiller PE Ratio falls into.


BUE:AZN
79GF Score
AstraZeneca PLC BUE:AZN
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

AstraZeneca E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, AstraZeneca's adjusted earnings per share data for the three months ended in Mar. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=2754.543/140.8000*140.8000
=2,754.543

Current CPI (Mar. 2026) = 140.8000.

AstraZeneca Quarterly Data

per share eps CPI Adj_EPS
201606 -0.033 101.000 -0.046
201609 11.933 101.500 16.553
201612 22.986 102.200 31.668
201703 6.475 102.700 8.877
201706 6.265 103.500 8.523
201709 9.463 104.300 12.775
201712 19.668 105.000 26.374
201803 5.440 105.100 7.288
201806 6.734 105.900 8.953
201809 12.512 106.600 16.526
201812 30.918 107.100 40.647
201903 18.372 107.000 24.175
201906 4.021 107.900 5.247
201909 12.863 108.400 16.708
201912 14.346 108.500 18.617
202003 36.621 108.600 47.479
202006 39.707 108.800 51.386
202009 36.378 109.200 46.905
202012 63.476 109.400 81.695
202103 106.294 109.700 136.428
202106 39.787 111.400 50.287
202109 -107.558 112.400 -134.735
202112 -22.218 114.700 -27.274
202203 26.843 116.500 32.442
202206 27.676 120.500 32.338
202209 145.897 122.300 167.966
202212 97.237 125.300 109.266
202303 229.158 126.800 254.459
202306 280.800 129.400 305.538
202309 307.956 130.100 333.284
202312 223.820 130.500 241.485
202403 1,179.500 131.600 1,261.957
202406 1,110.420 133.000 1,175.542
202409 864.955 133.500 912.252
202412 969.600 135.100 1,010.508
202503 1,993.489 136.100 2,062.331
202506 1,863.956 138.400 1,896.279
202509 2,199.980 138.900 2,230.073
202512 2,162.719 139.900 2,176.632
202603 2,754.543 140.800 2,754.543

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of ARS1,286.28 mean?
AstraZeneca (BUE:AZN) has a E10 of ARS1,286.28 as of Mar. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on AstraZeneca and its competitors.
Is AstraZeneca's E10 too high?
AstraZeneca's current E10 is ARS1,286.28. Overall, AstraZeneca has a GF Score™ of 79/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does AstraZeneca's E10 compare to LLY and JNJ?
AstraZeneca's E10 of ARS1,286.28 can be compared against companies in the Drug Manufacturers industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Drug Manufacturers company?
A good E10 depends on the Drug Manufacturers industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on AstraZeneca and its competitors. AstraZeneca's current E10 is ARS1,286.28. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is AstraZeneca stock overvalued right now?
Based on GuruFocus' analysis, AstraZeneca (BUE:AZN) is currently considered Fairly Valued. The stock's GF Value™ is ARS71,271.93, compared to a current price of ARS66,700.00 — trading 6.4% below its estimated fair value. The current E10 is ARS1,286.28. AstraZeneca's overall GF Score™ is 79/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For AstraZeneca (BUE:AZN), the current E10 is ARS1,286.28 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is AstraZeneca (BUE:AZN) Overvalued in 2026?

Based on GuruFocus' analysis, AstraZeneca stock appears to be undervalued. The current stock price of ARS66,700.00 is trading 6.4% below its estimated GF Value™ of ARS71,271.93. GuruFocus considers AstraZeneca to be Fairly Valued.

Key valuation signals for BUE:AZN:

  • E10: ARS1,286.28
  • GF Value™: ARS71,271.93 vs. price of ARS66,700.00 (6.4% below fair value)
  • GF Score™: 79/100 with 1 warning sign

No single metric tells the full story. See the BUE:AZN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


AstraZeneca Business Description

Address 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, GBR, CB2 0AA
A merger between Astra of Sweden and Zeneca of the United Kingdom formed AstraZeneca in 1999. The firm sells branded drugs across a number of major therapeutic areas, including oncology (over 40% of total revenue), cardiovascular, renal, and metabolic (over 20%), rare disease (16%), and respiratory and immunology (15%). The majority of sales comes from international markets, with the United States representing close to one-third of its sales.
79GF Score

Get the complete analysis for BUE:AZN

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

ARS66,700.00
Price
ARS71,271.93
GF Value