EPIX (ESSA Pharma) E10: $-2.61 (As of Jun. 2025)

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EPIX ESSA Pharma Inc EPIX
22 GF Score
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What is ESSA Pharma E10?

ESSA Pharma EPIX 22 E10 is $-2.61 as of Jun. 2025. GuruFocus rates EPIX with a GF Score™ of 22/100.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

ESSA Pharma's adjusted earnings per share data for the three months ended in Jun. 2025 was $-0.090. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is $-2.61 for the trailing ten years ended in Jun. 2025.

Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

As of today (2026-08-24), ESSA Pharma's current stock price is $0.2012. ESSA Pharma's E10 for the quarter that ended in Jun. 2025 was $-2.61. ESSA Pharma's Shiller PE Ratio of today is .


ESSA Pharma  (NAS:EPIX) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


ESSA Pharma E10 Related Terms


ESSA Pharma E10 Historical Data

* Premium members only.

The historical data trend for ESSA Pharma's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

ESSA Pharma E10 Chart

ESSA Pharma Annual Data
Trend Sep15 Sep16 Sep17 Sep18 Sep19 Sep20 Sep21 Sep22 Sep23 Sep24
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 -4.15 -3.96

ESSA Pharma Quarterly Data
Sep20 Dec20 Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -4.03 -3.96 -3.78 -3.33 -2.61

EPIX vs SLXN, NLSP, PTNT: E10 Comparison

For the Biotechnology subindustry, ESSA Pharma's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


ESSA Pharma Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, ESSA Pharma's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where ESSA Pharma's Shiller PE Ratio falls into.


EPIX
22GF Score
ESSA Pharma Inc EPIX
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ESSA Pharma E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, ESSA Pharma's adjusted earnings per share data for the three months ended in Jun. 2025 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Jun. 2025 (Change)*Current CPI (Jun. 2025)
=-0.09/129.8920*129.8920
=-0.090

Current CPI (Jun. 2025) = 129.8920.

ESSA Pharma Quarterly Data

per share eps CPI Adj_EPS
201509 1.400 100.421 1.811
201512 -3.600 99.947 -4.679
201603 -0.800 101.054 -1.028
201606 -2.600 102.002 -3.311
201609 -3.000 101.765 -3.829
201612 1.000 101.449 1.280
201703 -5.230 102.634 -6.619
201706 2.320 103.029 2.925
201709 -1.400 103.345 -1.760
201712 -1.440 103.345 -1.810
201803 -0.830 105.004 -1.027
201806 -0.500 105.557 -0.615
201809 -0.390 105.636 -0.480
201812 -0.430 105.399 -0.530
201903 -0.540 106.979 -0.656
201906 -0.520 107.690 -0.627
201909 -0.070 107.611 -0.084
201912 -0.220 107.769 -0.265
202003 -0.450 107.927 -0.542
202006 -0.240 108.401 -0.288
202009 -0.170 108.164 -0.204
202012 -0.200 108.559 -0.239
202103 -0.360 110.298 -0.424
202106 -0.210 111.720 -0.244
202109 -0.200 112.905 -0.230
202112 -0.210 113.774 -0.240
202203 -0.250 117.646 -0.276
202206 -0.200 120.806 -0.215
202209 -0.140 120.648 -0.151
202212 -0.150 120.964 -0.161
202303 -0.160 122.702 -0.169
202306 -0.170 124.203 -0.178
202309 -0.120 125.230 -0.124
202312 -0.140 125.072 -0.145
202403 -0.200 126.258 -0.206
202406 -0.160 127.522 -0.163
202409 -0.140 127.285 -0.143
202412 -0.190 127.364 -0.194
202503 -0.140 129.181 -0.141
202506 -0.090 129.892 -0.090

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of $-2.61 mean?
ESSA Pharma (EPIX) has a E10 of $-2.61 as of Jun. 2025. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on ESSA Pharma and its competitors.
Is ESSA Pharma's E10 too high?
ESSA Pharma's current E10 is $-2.61. Overall, ESSA Pharma has a GF Score™ of 22/100, reflecting its overall financial health beyond just this single metric.
How does ESSA Pharma's E10 compare to SLXN and NLSP?
ESSA Pharma's E10 of $-2.61 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on ESSA Pharma and its competitors. ESSA Pharma's current E10 is $-2.61. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is ESSA Pharma stock overvalued right now?
ESSA Pharma (EPIX) has a current E10 of $-2.61. The current E10 is $-2.61. ESSA Pharma's overall GF Score™ is 22/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For ESSA Pharma (EPIX), the current E10 is $-2.61 as of Jun. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

ESSA Pharma Business Description

Address 999 West Broadway Street, Suite 720, Vancouver, BC, CAN, V5Z 1K5
ESSA Pharma Inc is a pharmaceutical company. The company was focused on the development of small-molecule drugs for the treatment of castration-resistant prostate cancer. It was developing drugs that selectively block the amino-terminal domain of the androgen receptor, potentially overcoming the known AR-dependent resistance mechanisms of CRPC and providing CRPC patients with the potential for increased progression-free and overall survival. Currently, the company has terminated its clinical trials and other studies.
22GF Score

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