argenx SE (FRA:1AE) E10: €-0.46 (As of Mar. 2026)


FRA:1AE argenx SE FRA:1AE
80 GF Score
Price €777.80
GF Value €1,197.42
Valuation Significantly Undervalued
! 5 Warning Signs
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What is argenx SE E10?

argenx SE FRA:1AE +3.27% 80 E10 is €-0.46 as of Mar. 2026. GuruFocus rates FRA:1AE with a GF Score™ of 80/100 and a GF Value™ of €1,197.42 (Significantly Undervalued). The stock has 5 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

argenx SE's adjusted earnings per share data for the three months ended in Mar. 2026 was €4.775. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is €-0.46 for the trailing ten years ended in Mar. 2026.

During the past 3 years, the average E10 Growth Rate was 35.30% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of argenx SE was 35.30% per year. The lowest was 35.30% per year. And the median was 35.30% per year.

As of today (2026-06-28), argenx SE's current stock price is €777.80. argenx SE's E10 for the quarter that ended in Mar. 2026 was €-0.46. argenx SE's Shiller PE Ratio of today is .


argenx SE  (FRA:1AE) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


argenx SE E10 Related Terms


argenx SE E10 Historical Data

* Premium members only.

The historical data trend for argenx SE's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

argenx SE E10 Chart

argenx SE Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 -3.69 -3.98 -2.81 -0.98

argenx SE Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -2.57 -2.12 -1.74 -0.98 -0.46

FRA:1AE vs VRTX, REGN, ALNY: E10 Comparison

For the Biotechnology subindustry, argenx SE's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


argenx SE Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, argenx SE's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where argenx SE's Shiller PE Ratio falls into.


FRA:1AE
80GF Score
argenx SE FRA:1AE
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

argenx SE E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, argenx SE's adjusted earnings per share data for the three months ended in Mar. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=4.775/135.2700*135.2700
=4.775

Current CPI (Mar. 2026) = 135.2700.

argenx SE Quarterly Data

per share eps CPI Adj_EPS
201512 -0.314 99.730 -0.426
201603 -0.191 100.310 -0.258
201606 -0.214 100.260 -0.289
201609 -0.263 100.570 -0.354
201612 -0.395 100.710 -0.531
201703 -0.418 101.440 -0.557
201706 -0.013 101.370 -0.017
201709 -0.311 102.030 -0.412
201712 -0.377 101.970 -0.500
201803 -0.545 102.470 -0.719
201806 -0.038 103.100 -0.050
201809 -0.456 103.950 -0.593
201812 -0.828 103.970 -1.077
201903 0.169 105.370 0.217
201906 -1.376 105.840 -1.759
201909 -0.609 106.700 -0.772
201912 -2.399 106.800 -3.039
202006 0.000 107.510 0.000
202012 0.000 107.850 0.000
202103 -0.680 108.870 -0.845
202106 1.643 109.670 2.027
202109 -3.859 110.790 -4.712
202112 -4.106 114.010 -4.872
202203 -3.959 119.460 -4.483
202206 -3.595 119.050 -4.085
202209 -4.303 126.890 -4.587
202212 -0.661 124.940 -0.716
202303 -0.486 124.720 -0.527
202306 -1.560 125.830 -1.677
202309 -1.171 127.160 -1.246
202312 -1.550 126.450 -1.658
202403 -0.957 128.580 -1.007
202406 0.455 129.910 0.474
202409 1.252 131.610 1.287
202412 11.336 131.630 11.649
202503 2.386 133.330 2.421
202506 3.243 133.960 3.275
202509 4.413 135.920 4.392
202512 6.883 135.270 6.883
202603 4.775 135.270 4.775

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of €-0.46 mean?
argenx SE (FRA:1AE) has a E10 of €-0.46 as of Mar. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on argenx SE and its competitors.
Is argenx SE's E10 too high?
argenx SE's current E10 is €-0.46. Overall, argenx SE has a GF Score™ of 80/100 and is considered Significantly Undervalued, reflecting its overall financial health beyond just this single metric.
How does argenx SE's E10 compare to VRTX and REGN?
argenx SE's E10 of €-0.46 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on argenx SE and its competitors. argenx SE's current E10 is €-0.46. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is argenx SE stock overvalued right now?
Based on GuruFocus' analysis, argenx SE (FRA:1AE) is currently considered Significantly Undervalued. The stock's GF Value™ is €1,197.42, compared to a current price of €777.80 — trading 35% below its estimated fair value. The current E10 is €-0.46. argenx SE's overall GF Score™ is 80/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For argenx SE (FRA:1AE), the current E10 is €-0.46 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is argenx SE (FRA:1AE) Overvalued in 2026?

Based on GuruFocus' analysis, argenx SE stock appears to be undervalued. The current stock price of €777.80 is trading 35% below its estimated GF Value™ of €1,197.42. GuruFocus considers argenx SE to be Significantly Undervalued.

Key valuation signals for FRA:1AE:

  • E10: €-0.46
  • GF Value™: €1,197.42 vs. price of €777.80 (35% below fair value)
  • GF Score™: 80/100 with 5 warning signs

No single metric tells the full story. See the FRA:1AE stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


argenx SE Business Description

Address Laarderhoogtweg 25, Amsterdam, NH, NLD, 1101EB
Argenx is a Dutch biopharmaceutical company focused on developing antibody-based therapies for rare autoimmune diseases. The company's lead product, Vyvgart (efgartigimod), was approved by the FDA in December 2021 for the treatment of generalized myasthenia gravis (gMG). In 2022, Argenx also received FDA approval for Vyvgart Hytrulo, a subcutaneous formulation of Vyvgart, offering a more convenient option compared with Vyvgart's intravenous administration. In 2024, the FDA approved Vyvgart Hytrulo for Chronic Inflammatory Demyelinating Polyneuropathy, a rare immune-mediated neuromuscular disorder of the peripheral nervous system. Argenx is focused on innovation and developing its pipeline for treatments such as primary immune thrombocytopenia, thyroid eye disease, and Sjogren's Disease.
80GF Score

Get the complete analysis for FRA:1AE

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€777.80
Price
€1,197.42
GF Value