Celldex Therapeutics (FRA:TCE2) E10: €-6.22 (As of Mar. 2026)


FRA:TCE2 Celldex Therapeutics Inc FRA:TCE2
58 GF Score
Price €33.01
GF Value €6.14
Valuation Significantly Overvalued
! 8 Warning Signs
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What is Celldex Therapeutics E10?

Celldex Therapeutics FRA:TCE2 +3.64% 58 E10 is €-6.22 as of Mar. 2026. GuruFocus rates FRA:TCE2 with a GF Score™ of 58/100 and a GF Value™ of €6.14 (Significantly Overvalued). The stock has 8 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Celldex Therapeutics's adjusted earnings per share data for the three months ended in Mar. 2026 was €-1.021. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is €-6.22 for the trailing ten years ended in Mar. 2026.

During the past 3 years, the average E10 Growth Rate was 15.40% per year. During the past 5 years, the average E10 Growth Rate was 11.40% per year. During the past 10 years, the average E10 Growth Rate was 18.90% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of Celldex Therapeutics was 48.00% per year. The lowest was -15.00% per year. And the median was 9.40% per year.

As of today (2026-07-05), Celldex Therapeutics's current stock price is €33.01. Celldex Therapeutics's E10 for the quarter that ended in Mar. 2026 was €-6.22. Celldex Therapeutics's Shiller PE Ratio of today is .


Celldex Therapeutics  (FRA:TCE2) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Celldex Therapeutics E10 Related Terms


Celldex Therapeutics E10 Historical Data

* Premium members only.

The historical data trend for Celldex Therapeutics's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Celldex Therapeutics E10 Chart

Celldex Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only -12.61 -12.59 -11.09 -9.75 -6.61

Celldex Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -9.70 -7.94 -7.43 -6.61 -6.22

FRA:TCE2 vs TARS, KLRA, IRON: E10 Comparison

For the Biotechnology subindustry, Celldex Therapeutics's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Celldex Therapeutics Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Celldex Therapeutics's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Celldex Therapeutics's Shiller PE Ratio falls into.


FRA:TCE2
58GF Score
Celldex Therapeutics Inc FRA:TCE2
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Celldex Therapeutics E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Celldex Therapeutics's adjusted earnings per share data for the three months ended in Mar. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=-1.021/330.2130*330.2130
=-1.021

Current CPI (Mar. 2026) = 330.2130.

Celldex Therapeutics Quarterly Data

per share eps CPI Adj_EPS
201606 -4.272 241.018 -5.853
201609 -3.876 241.428 -5.301
201612 -4.266 241.432 -5.835
201703 -3.927 243.801 -5.319
201706 -3.070 244.955 -4.139
201709 -2.517 246.819 -3.367
201712 -0.177 246.524 -0.237
201803 -10.227 249.554 -13.532
201806 -1.430 251.989 -1.874
201809 -0.566 252.439 -0.740
201812 -0.712 251.233 -0.936
201903 -1.239 254.202 -1.609
201906 -0.743 256.143 -0.958
201909 -0.681 256.759 -0.876
201912 -0.576 256.974 -0.740
202003 -0.661 258.115 -0.846
202006 -0.444 257.797 -0.569
202009 -0.306 260.280 -0.388
202012 -0.452 260.474 -0.573
202103 -0.353 264.877 -0.440
202106 -0.282 271.696 -0.343
202109 -0.383 274.310 -0.461
202112 -0.381 278.802 -0.451
202203 -0.445 287.504 -0.511
202206 -0.728 296.311 -0.811
202209 -0.576 296.808 -0.641
202212 -0.529 296.797 -0.589
202303 -0.579 301.836 -0.633
202306 -0.600 305.109 -0.649
202309 -0.759 307.789 -0.814
202312 -0.770 306.746 -0.829
202403 -0.515 312.332 -0.544
202406 -0.502 314.175 -0.528
202409 -0.577 315.301 -0.604
202412 -0.678 315.605 -0.709
202503 -0.749 319.799 -0.773
202506 -0.737 322.561 -0.754
202509 -0.861 324.800 -0.875
202512 -1.042 324.054 -1.062
202603 -1.021 330.213 -1.021

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of €-6.22 mean?
Celldex Therapeutics (FRA:TCE2) has a E10 of €-6.22 as of Mar. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Celldex Therapeutics and its competitors.
Is Celldex Therapeutics' E10 too high?
Celldex Therapeutics' current E10 is €-6.22. Overall, Celldex Therapeutics has a GF Score™ of 58/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Celldex Therapeutics' E10 compare to TARS and KLRA?
Celldex Therapeutics' E10 of €-6.22 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Celldex Therapeutics and its competitors. Celldex Therapeutics's current E10 is €-6.22. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Celldex Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Celldex Therapeutics (FRA:TCE2) is currently considered Significantly Overvalued. The stock's GF Value™ is €6.14, compared to a current price of €33.01 — trading 437.6% above its estimated fair value. The current E10 is €-6.22. Celldex Therapeutics' overall GF Score™ is 58/100 with 8 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Celldex Therapeutics (FRA:TCE2), the current E10 is €-6.22 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Celldex Therapeutics (FRA:TCE2) Overvalued in 2026?

Based on GuruFocus' analysis, Celldex Therapeutics stock appears to be overvalued. The current stock price of €33.01 is trading 437.6% above its estimated GF Value™ of €6.14. GuruFocus considers Celldex Therapeutics to be Significantly Overvalued.

Key valuation signals for FRA:TCE2:

  • E10: €-6.22
  • GF Value™: €6.14 vs. price of €33.01 (437.6% above fair value)
  • GF Score™: 58/100 with 8 warning signs

No single metric tells the full story. See the FRA:TCE2 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Celldex Therapeutics Business Description

Other Exchanges CLDX:USA
Address 53 Frontage Road, Suite 220, Perryville III Building, Hampton, NJ, USA, 08827
Celldex Therapeutics Inc is a biopharmaceutical firm focused on mast cell biology and the development of therapeutic antibodies. Its pipeline includes monoclonal and bispecific antibodies aimed at treating severe inflammatory, allergic, autoimmune, and other mast cell-mediated diseases. The company operates in a single operating and reportable segment in the business of development, manufacturing and commercialization of novel therapeutics for human health care.
58GF Score

Get the complete analysis for FRA:TCE2

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€33.01
Price
€6.14
GF Value