KYKOF (Kyowa Kirin Co) E10: $0.71 (As of Dec. 2025)


KYKOF Kyowa Kirin Co Ltd KYKOF
82 GF Score
Price $14.43
GF Value $17.92
Valuation Modestly Undervalued
! 1 Warning Sign
View Full Analysis

What is Kyowa Kirin Co E10?

Kyowa Kirin Co KYKOF 82 E10 is $0.71 as of Dec. 2025. GuruFocus rates KYKOF with a GF Score™ of 82/100 and a GF Value™ of $17.92 (Modestly Undervalued). The stock has 1 warning sign investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Kyowa Kirin Co's adjusted earnings per share data for the three months ended in Dec. 2025 was $0.422. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is $0.71 for the trailing ten years ended in Dec. 2025.

During the past 12 months, Kyowa Kirin Co's average E10 Growth Rate was 8.40% per year. During the past 3 years, the average E10 Growth Rate was 11.50% per year. During the past 5 years, the average E10 Growth Rate was 11.30% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of Kyowa Kirin Co was 12.40% per year. The lowest was 8.40% per year. And the median was 11.00% per year.

As of today (2026-06-26), Kyowa Kirin Co's current stock price is $14.425. Kyowa Kirin Co's E10 for the quarter that ended in Dec. 2025 was $0.71. Kyowa Kirin Co's Shiller PE Ratio of today is 20.32.

During the past 13 years, the highest Shiller PE Ratio of Kyowa Kirin Co was 60.48. The lowest was 19.72. And the median was 37.24.


Kyowa Kirin Co  (OTCPK:KYKOF) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.

Kyowa Kirin Co's Shiller P/E Ratio of today is calculated as

Shiller PE Ratio=Share Price/E10
=14.425/0.71
=20.32

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Shiller P/E Ratio of Kyowa Kirin Co was 60.48. The lowest was 19.72. And the median was 37.24.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Kyowa Kirin Co E10 Related Terms


Kyowa Kirin Co E10 Historical Data

* Premium members only.

The historical data trend for Kyowa Kirin Co's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Kyowa Kirin Co E10 Chart

Kyowa Kirin Co Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.67 0.60 0.66 0.66 0.71

Kyowa Kirin Co Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.71 0.65 0.80 0.71 0.00

KYKOF vs ZTS: E10 Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Kyowa Kirin Co's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Kyowa Kirin Co Shiller PE Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Kyowa Kirin Co's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Kyowa Kirin Co's Shiller PE Ratio falls into.


KYKOF
82GF Score
Kyowa Kirin Co Ltd KYKOF
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Kyowa Kirin Co E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Kyowa Kirin Co's adjusted earnings per share data for the three months ended in Dec. 2025 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Dec. 2025 (Change)*Current CPI (Dec. 2025)
=0.422/113.0000*113.0000
=0.422

Current CPI (Dec. 2025) = 113.0000.

Kyowa Kirin Co Quarterly Data

per share eps CPI Adj_EPS
201603 0.120 97.900 0.139
201606 0.058 98.100 0.067
201609 0.102 98.000 0.118
201612 0.220 98.400 0.253
201703 0.194 98.100 0.223
201706 0.137 98.500 0.157
201709 0.150 98.800 0.172
201712 0.217 99.400 0.247
201803 0.379 99.200 0.432
201806 0.203 99.200 0.231
201809 0.214 99.900 0.242
201812 0.114 99.700 0.129
201903 0.135 99.700 0.153
201906 0.688 99.800 0.779
201909 0.143 100.100 0.161
201912 0.184 100.500 0.207
202003 0.239 100.300 0.269
202006 0.241 99.900 0.273
202009 0.171 99.900 0.193
202012 0.171 99.300 0.195
202103 0.221 99.900 0.250
202106 0.205 99.500 0.233
202109 0.132 100.100 0.149
202112 0.318 100.100 0.359
202203 0.252 101.100 0.282
202206 0.264 101.800 0.293
202209 0.184 103.100 0.202
202212 0.060 104.100 0.065
202303 0.178 104.400 0.193
202306 0.117 105.200 0.126
202309 0.401 106.200 0.427
202312 0.357 106.800 0.378
202403 0.182 107.200 0.192
202406 0.276 108.200 0.288
202409 0.241 108.900 0.250
202412 0.051 110.700 0.052
202503 0.079 111.100 0.080
202506 0.134 111.700 0.136
202509 0.210 112.000 0.212
202512 0.422 113.000 0.422

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of $0.71 mean?
Kyowa Kirin Co (KYKOF) has a E10 of $0.71 as of Dec. 2025. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Kyowa Kirin Co and its competitors.
Is Kyowa Kirin Co's E10 too high?
Kyowa Kirin Co's current E10 is $0.71. Overall, Kyowa Kirin Co has a GF Score™ of 82/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Kyowa Kirin Co's E10 compare to ZTS?
Kyowa Kirin Co's E10 of $0.71 can be compared against companies in the Drug Manufacturers industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Drug Manufacturers company?
A good E10 depends on the Drug Manufacturers industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Kyowa Kirin Co and its competitors. Kyowa Kirin Co's current E10 is $0.71. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Kyowa Kirin Co stock overvalued right now?
Based on GuruFocus' analysis, Kyowa Kirin Co (KYKOF) is currently considered Modestly Undervalued. The stock's GF Value™ is $17.92, compared to a current price of $14.43 — trading 19.5% below its estimated fair value. The current E10 is $0.71. Kyowa Kirin Co's overall GF Score™ is 82/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Kyowa Kirin Co (KYKOF), the current E10 is $0.71 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Kyowa Kirin Co (KYKOF) Overvalued in 2026?

Based on GuruFocus' analysis, Kyowa Kirin Co stock appears to be undervalued. The current stock price of $14.43 is trading 19.5% below its estimated GF Value™ of $17.92. GuruFocus considers Kyowa Kirin Co to be Modestly Undervalued.

Key valuation signals for KYKOF:

  • E10: $0.71
  • GF Value™: $17.92 vs. price of $14.43 (19.5% below fair value)
  • GF Score™: 82/100 with 1 warning sign

No single metric tells the full story. See the KYKOF stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Kyowa Kirin Co Business Description

Address 1-9-2 Otemachi, Chiyoda-ku, Chiyoda-ku, Tokyo, JPN, 100-0004
Kyowa Kirin Co Ltd is engaged in research, development, manufacturing, sales, import and export of prescription pharmaceuticals. Its products include KHK4083/AMG 451, rocatinlimab; ziftomenib; OTL-203 KK8398, infigratinib; KHK4951, tivozanib; OTL-201; KK4277; KK2260; KK2269; KK2845; and KK8123.
82GF Score

Get the complete analysis for KYKOF

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$14.43
Price
$17.92
GF Value