SCYNEXIS (LTS:0L49) E10: $-39.24 (As of Jun. 2026)

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Director of Data and Quant Analytics at GuruFocus
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Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

LTS:0L49 SCYNEXIS Inc LTS:0L49
45 GF Score
Price $5.27
GF Value $17.91
Valuation Possible Value Trap
! 3 Warning Signs
View Full Analysis

What is SCYNEXIS E10?

SCYNEXIS LTS:0L49 +8.49% 45 E10 is $-39.24 as of Jun. 2026. GuruFocus rates LTS:0L49 with a GF Score™ of 45/100 and a GF Value™ of $17.91 (Possible Value Trap). The stock has 3 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

SCYNEXIS's adjusted earnings per share data for the three months ended in Jun. 2026 was $0.630. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is $-39.24 for the trailing ten years ended in Jun. 2026.

During the past 3 years, the average E10 Growth Rate was 50.40% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of SCYNEXIS was 50.40% per year. The lowest was 50.40% per year. And the median was 50.40% per year.

As of today (2026-08-16), SCYNEXIS's current stock price is $5.2726. SCYNEXIS's E10 for the quarter that ended in Jun. 2026 was $-39.24. SCYNEXIS's Shiller PE Ratio of today is .


SCYNEXIS  (LTS:0L49) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


SCYNEXIS E10 Related Terms


SCYNEXIS E10 Historical Data

* Premium members only.

The historical data trend for SCYNEXIS's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

SCYNEXIS E10 Chart

SCYNEXIS Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 -49.47 -11.51 -9.05 -5.93

SCYNEXIS Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -7.70 -7.16 -5.93 -5.38 -39.24

LTS:0L49 vs IXHL, ETST, INIS: E10 Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, SCYNEXIS's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


SCYNEXIS Shiller PE Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, SCYNEXIS's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where SCYNEXIS's Shiller PE Ratio falls into.


LTS:0L49
45GF Score
SCYNEXIS Inc LTS:0L49
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

SCYNEXIS E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, SCYNEXIS's adjusted earnings per share data for the three months ended in Jun. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=0.63/333.9520*333.9520
=0.630

Current CPI (Jun. 2026) = 333.9520.

SCYNEXIS Quarterly Data

per share eps CPI Adj_EPS
201609 -38.400 241.428 -53.116
201612 -4.000 241.432 -5.533
201703 -20.000 243.801 -27.395
201706 -12.800 244.955 -17.450
201709 -24.800 246.819 -33.555
201712 -21.600 246.524 -29.260
201803 -9.600 249.554 -12.847
201806 -18.400 251.989 -24.385
201809 0.800 252.439 1.058
201812 4.800 251.233 6.380
201903 -36.800 254.202 -48.345
201906 -12.640 256.143 -16.480
201909 -11.600 256.759 -15.087
201912 -17.120 256.974 -22.248
202003 -5.760 258.115 -7.452
202006 -5.120 257.797 -6.632
202009 -2.240 260.280 -2.874
202012 -31.360 260.474 -40.206
202103 -1.840 264.877 -2.320
202106 -1.760 271.696 -2.163
202109 -0.480 274.310 -0.584
202112 -8.880 278.802 -10.637
202203 -1.440 287.504 -1.673
202206 -2.480 296.311 -2.795
202209 -4.960 296.808 -5.581
202212 -2.320 296.797 -2.610
202303 -5.680 301.836 -6.284
202306 19.680 305.109 21.540
202309 -0.320 307.789 -0.347
202312 -3.280 306.746 -3.571
202403 0.080 312.332 0.086
202406 -2.400 314.175 -2.551
202409 -0.480 315.301 -0.508
202412 -0.720 315.605 -0.762
202503 -0.880 319.799 -0.919
202506 -1.110 322.561 -1.149
202509 -1.360 324.800 -1.398
202512 2.000 324.054 2.061
202603 -3.360 330.213 -3.398
202606 0.630 333.952 0.630

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of $-39.24 mean?
SCYNEXIS (LTS:0L49) has a E10 of $-39.24 as of Jun. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on SCYNEXIS and its competitors.
Is SCYNEXIS's E10 too high?
SCYNEXIS's current E10 is $-39.24. Overall, SCYNEXIS has a GF Score™ of 45/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does SCYNEXIS's E10 compare to IXHL and ETST?
SCYNEXIS's E10 of $-39.24 can be compared against companies in the Drug Manufacturers industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Drug Manufacturers company?
A good E10 depends on the Drug Manufacturers industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on SCYNEXIS and its competitors. SCYNEXIS's current E10 is $-39.24. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is SCYNEXIS stock overvalued right now?
Based on GuruFocus' analysis, SCYNEXIS (LTS:0L49) is currently considered Possible Value Trap. The stock's GF Value™ is $17.91, compared to a current price of $5.27 — trading 70.6% below its estimated fair value. The current E10 is $-39.24. SCYNEXIS's overall GF Score™ is 45/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For SCYNEXIS (LTS:0L49), the current E10 is $-39.24 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is SCYNEXIS (LTS:0L49) Overvalued in 2026?

Based on GuruFocus' analysis, SCYNEXIS stock appears to be undervalued. The current stock price of $5.27 is trading 70.6% below its estimated GF Value™ of $17.91. GuruFocus considers SCYNEXIS to be Possible Value Trap.

Key valuation signals for LTS:0L49:

  • E10: $-39.24
  • GF Value™: $17.91 vs. price of $5.27 (70.6% below fair value)
  • GF Score™: 45/100 with 3 warning signs

No single metric tells the full story. See the LTS:0L49 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


SCYNEXIS Business Description

Other Exchanges SCYX:USA135:Germany
Address 1 Evertrust Plaza, 13th Floor, Jersey City, NJ, USA, 07302 - 6548
SCYNEXIS Inc is a drug development company that focuses on the development and commercialization of novel anti-infectives to address unmet therapeutic needs. It is engaged in developing a product candidate, ibrexafungerp which is a novel oral and intravenous (IV) drug for the treatment of several fungal infections, including serious and life-threatening invasive fungal infections. The ibrexafungerp is a novel and structurally distinct triterpenoid glucan synthase inhibitor that is effective in vitro and in vivo against broad range of Candida and Aspergillus species, including drug-resistant strains as well as Pneumocystis, Coccidioides, Histoplasma and Blastomyces genera and some common mucorales species.
45GF Score

Get the complete analysis for LTS:0L49

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$5.27
Price
$17.91
GF Value