argenx SE (MEX:ARGXN) E10: MXN4.92 (As of Jun. 2026)

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MEX:ARGXN argenx SE MEX:ARGXN
79 GF Score
Price MXN14,892.29
GF Value MXN21,883.47
Valuation Significantly Undervalued
! 5 Warning Signs
View Full Analysis

What is argenx SE E10?

argenx SE MEX:ARGXN 79 E10 is MXN4.92 as of Jun. 2026. GuruFocus rates MEX:ARGXN with a GF Score™ of 79/100 and a GF Value™ of MXN21,883.47 (Significantly Undervalued). The stock has 5 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

argenx SE's adjusted earnings per share data for the three months ended in Jun. 2026 was MXN130.519. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is MXN4.92 for the trailing ten years ended in Jun. 2026.

During the past 3 years, the average E10 Growth Rate was 35.30% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of argenx SE was 35.30% per year. The lowest was 35.30% per year. And the median was 35.30% per year.

As of today (2026-09-01), argenx SE's current stock price is MXN14892.29. argenx SE's E10 for the quarter that ended in Jun. 2026 was MXN4.92. argenx SE's Shiller PE Ratio of today is 3,026.89.

During the past 13 years, the highest Shiller PE Ratio of argenx SE was 3608.00. The lowest was 2920.80. And the median was 3136.40.


argenx SE  (MEX:ARGXN) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.

argenx SE's Shiller P/E Ratio of today is calculated as

Shiller PE Ratio=Share Price/E10
=14892.29/4.92
=3,026.89

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Shiller P/E Ratio of argenx SE was 3608.00. The lowest was 2920.80. And the median was 3136.40.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


argenx SE E10 Related Terms


argenx SE E10 Historical Data

* Premium members only.

The historical data trend for argenx SE's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

argenx SE E10 Chart

argenx SE Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 -77.15 -98.40 -57.51 -20.75

argenx SE Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -52.34 -40.52 -20.75 -9.84 4.92

MEX:ARGXN vs VRTX, REGN, MRNA: E10 Comparison

For the Biotechnology subindustry, argenx SE's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


argenx SE Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, argenx SE's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where argenx SE's Shiller PE Ratio falls into.


MEX:ARGXN
79GF Score
argenx SE MEX:ARGXN
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

argenx SE E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, argenx SE's adjusted earnings per share data for the three months ended in Jun. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=130.519/137.7700*137.7700
=130.519

Current CPI (Jun. 2026) = 137.7700.

argenx SE Quarterly Data

per share eps CPI Adj_EPS
201603 -3.667 100.310 -5.036
201606 -4.444 100.260 -6.107
201609 -5.709 100.570 -7.821
201612 -8.583 100.710 -11.741
201703 -8.408 101.440 -11.419
201706 -0.261 101.370 -0.355
201709 -6.722 102.030 -9.077
201712 -8.756 101.970 -11.830
201803 -12.205 102.470 -16.410
201806 -0.874 103.100 -1.168
201809 -9.958 103.950 -13.198
201812 -18.498 103.970 -24.512
201903 3.703 105.370 4.842
201906 -29.873 105.840 -38.885
201909 -13.248 106.700 -17.106
201912 -50.279 106.800 -64.859
202006 0.000 107.510 0.000
202012 0.000 107.850 0.000
202103 -16.557 108.870 -20.952
202106 39.414 109.670 49.513
202109 -93.351 110.790 -116.084
202112 -95.185 114.010 -115.022
202203 -86.812 119.460 -100.118
202206 -76.448 119.050 -88.469
202209 -85.690 126.890 -93.037
202212 -13.647 124.940 -15.048
202303 -9.373 124.720 -10.354
202306 -28.973 125.830 -31.722
202309 -21.774 127.160 -23.591
202312 -28.686 126.450 -31.254
202403 -17.260 128.580 -18.494
202406 8.977 129.910 9.520
202409 27.370 131.610 28.651
202412 247.557 131.630 259.105
202503 52.782 133.330 54.540
202506 70.421 133.960 72.424
202509 95.023 135.920 96.316
202512 145.126 135.270 147.808
202603 99.541 136.910 100.166
202606 130.519 137.770 130.519

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of MXN4.92 mean?
argenx SE (MEX:ARGXN) has a E10 of MXN4.92 as of Jun. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on argenx SE and its competitors.
Is argenx SE's E10 too high?
argenx SE's current E10 is MXN4.92. Overall, argenx SE has a GF Score™ of 79/100 and is considered Significantly Undervalued, reflecting its overall financial health beyond just this single metric.
How does argenx SE's E10 compare to VRTX and REGN?
argenx SE's E10 of MXN4.92 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on argenx SE and its competitors. argenx SE's current E10 is MXN4.92. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is argenx SE stock overvalued right now?
Based on GuruFocus' analysis, argenx SE (MEX:ARGXN) is currently considered Significantly Undervalued. The stock's GF Value™ is MXN21,883.47, compared to a current price of MXN14,892.29 — trading 31.9% below its estimated fair value. The current E10 is MXN4.92. argenx SE's overall GF Score™ is 79/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For argenx SE (MEX:ARGXN), the current E10 is MXN4.92 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is argenx SE (MEX:ARGXN) Overvalued in 2026?

Based on GuruFocus' analysis, argenx SE stock appears to be undervalued. The current stock price of MXN14,892.29 is trading 31.9% below its estimated GF Value™ of MXN21,883.47. GuruFocus considers argenx SE to be Significantly Undervalued.

Key valuation signals for MEX:ARGXN:

  • E10: MXN4.92
  • GF Value™: MXN21,883.47 vs. price of MXN14,892.29 (31.9% below fair value)
  • GF Score™: 79/100 with 5 warning signs

No single metric tells the full story. See the MEX:ARGXN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


argenx SE Business Description

Address Laarderhoogtweg 25, Amsterdam, NH, NLD, 1101EB
Argenx is a Dutch biopharmaceutical company focused on developing antibody-based therapies for rare autoimmune diseases. The company's lead product, Vyvgart (efgartigimod), was approved by the FDA in December 2021 for the treatment of generalized myasthenia gravis (gMG). In 2022, Argenx also received FDA approval for Vyvgart Hytrulo, a subcutaneous formulation of Vyvgart, offering a more convenient option compared with Vyvgart's intravenous administration. In 2024, the FDA approved Vyvgart Hytrulo for Chronic Inflammatory Demyelinating Polyneuropathy, a rare immune-mediated neuromuscular disorder of the peripheral nervous system. Argenx is focused on innovation and developing its pipeline for treatments such as primary immune thrombocytopenia, thyroid eye disease, and Sjogren's Disease.
79GF Score

Get the complete analysis for MEX:ARGXN

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN14,892.29
Price
MXN21,883.47
GF Value