MTVA (MetaVia) E10: $-53,419.11 (As of Mar. 2026)

Author: Vera Yuan Vera Yuan
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Director of Data and Quant Analytics at GuruFocus
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Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

MTVA MetaVia Inc MTVA
30 GF Score
Price $1.42
! 1 Warning Sign
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What is MetaVia E10?

MetaVia MTVA -1.39% 30 E10 is $-53,419.11 as of Mar. 2026. GuruFocus rates MTVA with a GF Score™ of 30/100. The stock has 1 warning sign investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

MetaVia's adjusted earnings per share data for the three months ended in Mar. 2026 was $-0.790. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is $-53,419.11 for the trailing ten years ended in Mar. 2026.

Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

As of today (2026-08-01), MetaVia's current stock price is $1.42. MetaVia's E10 for the quarter that ended in Mar. 2026 was $-53,419.11. MetaVia's Shiller PE Ratio of today is .


MetaVia  (NAS:MTVA) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


MetaVia E10 Related Terms


MetaVia E10 Historical Data

* Premium members only.

The historical data trend for MetaVia's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

MetaVia E10 Chart

MetaVia Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 -65,701.31 -54,627.40

MetaVia Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -61,901.63 -60,725.07 -58,474.63 -54,627.40 -53,419.11

MTVA vs CNSP, TRAW, APRE: E10 Comparison

For the Biotechnology subindustry, MetaVia's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


MetaVia Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, MetaVia's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where MetaVia's Shiller PE Ratio falls into.


MTVA
30GF Score
MetaVia Inc MTVA
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
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MetaVia E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, MetaVia's adjusted earnings per share data for the three months ended in Mar. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=-0.79/330.2130*330.2130
=-0.790

Current CPI (Mar. 2026) = 330.2130.

MetaVia Quarterly Data

per share eps CPI Adj_EPS
201606 -10,007.194 241.018 -13,710.617
201609 -28,178.571 241.428 -38,541.223
201612 -51,528.571 241.432 -70,477.004
201703 -46,850.000 243.801 -63,455.355
201706 -65,637.500 244.955 -88,483.010
201709 -53,857.143 246.819 -72,054.132
201712 -41,900.621 246.524 -56,124.879
201803 -33,600.000 249.554 -44,459.944
201806 -31,060.465 251.989 -40,702.449
201809 -28,143.519 252.439 -36,814.263
201812 20,611.111 251.233 27,090.616
201903 -11,407.407 254.202 -14,818.428
201906 -976.800 256.143 -1,259.266
201909 -1,848.000 256.759 -2,376.679
201912 -6,679.200 256.974 -8,582.809
202003 -792.000 258.115 -1,013.225
202006 -396.000 257.797 -507.238
202009 -501.600 260.280 -636.372
202012 -3,168.000 260.474 -4,016.197
202103 -396.000 264.877 -493.680
202106 -475.200 271.696 -577.547
202109 -410.080 274.310 -493.652
202112 -460.240 278.802 -545.108
202203 -285.120 287.504 -327.475
202206 -327.360 296.311 -364.814
202209 -308.000 296.808 -342.665
202212 -16.177 296.797 -17.998
202303 -5.610 301.836 -6.137
202306 -1.650 305.109 -1.786
202309 -8.250 307.789 -8.851
202312 -11.550 306.746 -12.434
202403 -14.520 312.332 -15.351
202406 -20.350 314.175 -21.389
202409 -6.050 315.301 -6.336
202412 -3.490 315.605 -3.652
202503 -3.930 319.799 -4.058
202506 -2.860 322.561 -2.928
202509 -1.540 324.800 -1.566
202512 -0.420 324.054 -0.428
202603 -0.790 330.213 -0.790

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of $-53,419.11 mean?
MetaVia (MTVA) has a E10 of $-53,419.11 as of Mar. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on MetaVia and its competitors.
Is MetaVia's E10 too high?
MetaVia's current E10 is $-53,419.11. Overall, MetaVia has a GF Score™ of 30/100, reflecting its overall financial health beyond just this single metric.
How does MetaVia's E10 compare to CNSP and TRAW?
MetaVia's E10 of $-53,419.11 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on MetaVia and its competitors. MetaVia's current E10 is $-53,419.11. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is MetaVia stock overvalued right now?
MetaVia (MTVA) has a current E10 of $-53,419.11. The current E10 is $-53,419.11. MetaVia's overall GF Score™ is 30/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For MetaVia (MTVA), the current E10 is $-53,419.11 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

MetaVia Business Description

Address 545 Concord Avenue, Suite 210, Cambridge, MA, USA, 02138
MetaVia Inc is a clinical-stage biotechnology company focused on developing novel pharmaceuticals to treat cardiometabolic diseases. It has two programs focused on the treatment of metabolic dysfunction-associated steatohepatitis (MASH) and obesity. Vanoglipel (DA-1241) is a novel GPR119 (GPR119) agonist with development optionality as a standalone or combination therapy for both MASH and Type 2 Diabetes Mellitus (T2DM). Agonism of GPR119 in the gut promotes the release of key gut peptides, glucagon-like peptide-1 (GLP-1), glucagon-dependent insulinotropic polypeptide receptor (GIP), and peptide YY.
30GF Score

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E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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