PKTX (ProtoKinetix) E10: $0.00 (As of Sep. 2025)


What is ProtoKinetix E10?

ProtoKinetix PKTX +13.46% E10 is $0.00 as of Sep. 2025. The stock has 1 warning sign investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

ProtoKinetix's adjusted earnings per share data for the three months ended in Sep. 2025 was $0.000. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is $0.00 for the trailing ten years ended in Sep. 2025.

Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of ProtoKinetix was 26.30% per year. The lowest was 12.60% per year. And the median was 20.60% per year.

As of today (2026-06-27), ProtoKinetix's current stock price is $0.0059. ProtoKinetix's E10 for the quarter that ended in Sep. 2025 was $0.00. ProtoKinetix's Shiller PE Ratio of today is .


ProtoKinetix  (OTCPK:PKTX) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


ProtoKinetix E10 Related Terms


ProtoKinetix E10 Historical Data

* Premium members only.

The historical data trend for ProtoKinetix's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

ProtoKinetix E10 Chart

ProtoKinetix Annual Data
Trend Dec15 Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 -0.01 0.00 -0.02 0.00

ProtoKinetix Quarterly Data
Dec20 Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.00

PKTX vs BBLG, JAGX, VBIO: E10 Comparison

For the Biotechnology subindustry, ProtoKinetix's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


ProtoKinetix Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, ProtoKinetix's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where ProtoKinetix's Shiller PE Ratio falls into.



ProtoKinetix E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, ProtoKinetix's adjusted earnings per share data for the three months ended in Sep. 2025 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Sep. 2025 (Change)*Current CPI (Sep. 2025)
=0/324.8000*324.8000
=0.000

Current CPI (Sep. 2025) = 324.8000.

ProtoKinetix Quarterly Data

per share eps CPI Adj_EPS
201512 -0.002 236.525 -0.003
201603 -0.002 238.132 -0.003
201606 -0.002 241.018 -0.003
201609 -0.002 241.428 -0.003
201612 -0.002 241.432 -0.003
201703 -0.002 243.801 -0.003
201706 -0.001 244.955 -0.001
201709 -0.001 246.819 -0.001
201712 -0.006 246.524 -0.008
201803 -0.001 249.554 -0.001
201806 -0.001 251.989 -0.001
201809 -0.001 252.439 -0.001
201812 -0.001 251.233 -0.001
201903 -0.001 254.202 -0.001
201906 -0.003 256.143 -0.004
201909 -0.002 256.759 -0.003
201912 -0.010 256.974 -0.013
202003 -0.010 258.115 -0.013
202006 -0.008 257.797 -0.010
202009 -0.006 260.280 -0.007
202012 0.000 260.474 0.000
202103 0.000 264.877 0.000
202106 -0.001 271.696 -0.001
202109 -0.010 274.310 -0.012
202112 -0.001 278.802 -0.001
202203 -0.010 287.504 -0.011
202206 -0.002 296.311 -0.002
202209 -0.001 296.808 -0.001
202212 0.000 296.797 0.000
202303 -0.010 301.836 -0.011
202306 -0.010 305.109 -0.011
202309 -0.010 307.789 -0.011
202312 -0.009 306.746 -0.010
202403 0.000 312.332 0.000
202406 0.000 314.175 0.000
202409 0.000 315.301 0.000
202412 0.000 315.605 0.000
202503 0.000 319.799 0.000
202506 0.000 322.561 0.000
202509 0.000 324.800 0.000

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of $0.00 mean?
ProtoKinetix (PKTX) has a E10 of $0.00 as of Sep. 2025. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on ProtoKinetix and its competitors.
Is ProtoKinetix's E10 too high?
ProtoKinetix's current E10 is $0.00.
How does ProtoKinetix's E10 compare to BBLG and JAGX?
ProtoKinetix's E10 of $0.00 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on ProtoKinetix and its competitors. ProtoKinetix's current E10 is $0.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is ProtoKinetix stock overvalued right now?
ProtoKinetix (PKTX) has a current E10 of $0.00. The current E10 is $0.00. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For ProtoKinetix (PKTX), the current E10 is $0.00 as of Sep. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

ProtoKinetix Business Description

Address 109 W Main Street, Dalton, OH, USA, 44618
ProtoKinetix Inc is a research and development stage biotechnology company focused on scientific medical research of AFGPs (Anti-Freeze Glycoproteins). The AFGP is a compound produced by fish, insects, reptiles, bacteria, and plants that enable survival in freezing temperatures. The company also develops AFGP applications which include regenerative medicine issues including harvesting, processing, storage, and transplanting cells, tissues, and organs and treatments for chronic inflammatory conditions and diseases caused by stress factors, including UV radiation, oxidation, and cryopreservation and hydrogen peroxide.