Eisai Co (TSE:4523) E10: 円661.33 (As of Mar. 2026)


TSE:4523 Eisai Co Ltd TSE:4523
64 GF Score
Price 円4,145.00
GF Value 円5,703.17
Valuation Modestly Undervalued
! 7 Warning Signs
View Full Analysis

What is Eisai Co E10?

Eisai Co TSE:4523 +3.86% 64 E10 is 円661.33 as of Mar. 2026. GuruFocus rates TSE:4523 with a GF Score™ of 64/100 and a GF Value™ of 円5,703.17 (Modestly Undervalued). The stock has 7 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Eisai Co's adjusted earnings per share data for the three months ended in Mar. 2026 was 円-11.530. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is 円661.33 for the trailing ten years ended in Mar. 2026.

During the past 12 months, Eisai Co's average E10 Growth Rate was -8.80% per year. During the past 3 years, the average E10 Growth Rate was -5.10% per year. During the past 5 years, the average E10 Growth Rate was -3.00% per year. During the past 10 years, the average E10 Growth Rate was 2.30% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of Eisai Co was 10.50% per year. The lowest was -5.10% per year. And the median was 1.30% per year.

As of today (2026-06-29), Eisai Co's current stock price is 円4145.00. Eisai Co's E10 for the quarter that ended in Mar. 2026 was 円661.33. Eisai Co's Shiller PE Ratio of today is 6.27.

During the past 13 years, the highest Shiller PE Ratio of Eisai Co was 18.12. The lowest was 4.89. And the median was 9.91.


Eisai Co  (TSE:4523) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.

Eisai Co's Shiller P/E Ratio of today is calculated as

Shiller PE Ratio=Share Price/E10
=4145.00/661.33
=6.27

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Shiller P/E Ratio of Eisai Co was 18.12. The lowest was 4.89. And the median was 9.91.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Eisai Co E10 Related Terms


Eisai Co E10 Historical Data

* Premium members only.

The historical data trend for Eisai Co's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Eisai Co E10 Chart

Eisai Co Annual Data
Trend Mar17 Mar18 Mar19 Mar20 Mar21 Mar22 Mar23 Mar24 Mar25 Mar26
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 786.80 773.69 750.05 725.27 661.33

Eisai Co Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 725.27 725.69 722.37 691.02 661.33

TSE:4523 vs ZTS, UTHR: E10 Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Eisai Co's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Eisai Co Shiller PE Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Eisai Co's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Eisai Co's Shiller PE Ratio falls into.


TSE:4523
64GF Score
Eisai Co Ltd TSE:4523
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Eisai Co E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Eisai Co's adjusted earnings per share data for the three months ended in Mar. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=-11.53/112.7000*112.7000
=-11.530

Current CPI (Mar. 2026) = 112.7000.

Eisai Co Quarterly Data

per share eps CPI Adj_EPS
201606 275.680 98.100 316.709
201609 114.120 98.000 131.238
201612 146.760 98.400 168.088
201703 13.080 98.100 15.027
201706 136.960 98.500 156.704
201709 125.880 98.800 143.590
201712 129.680 99.400 147.032
201803 331.360 99.200 376.454
201806 171.760 99.200 195.135
201809 283.880 99.900 320.253
201812 102.200 99.700 115.526
201903 326.640 99.700 369.231
201906 302.400 99.800 341.488
201909 74.280 100.100 83.630
201912 645.480 100.500 723.837
202003 677.000 100.300 760.697
202006 340.800 99.900 384.466
202009 19.120 99.900 21.570
202012 270.240 99.300 306.707
202103 -45.000 99.900 -50.766
202106 587.440 99.500 665.372
202109 54.880 100.100 61.788
202112 197.520 100.100 222.383
202203 -42.723 101.100 -47.625
202206 93.810 101.800 103.854
202209 12.440 103.100 13.598
202212 30.140 104.100 32.630
202303 56.920 104.400 61.445
202306 70.920 105.200 75.976
202309 19.730 106.200 20.938
202312 20.810 106.800 21.960
202403 46.400 107.200 48.781
202406 36.950 108.200 38.487
202409 39.180 108.900 40.547
202412 84.010 110.700 85.528
202503 3.620 111.100 3.672
202506 51.350 111.700 51.810
202509 36.020 112.000 36.245
202512 60.940 113.000 60.778
202603 -11.530 112.700 -11.530

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of 円661.33 mean?
Eisai Co (TSE:4523) has a E10 of 円661.33 as of Mar. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Eisai Co and its competitors.
Is Eisai Co's E10 too high?
Eisai Co's current E10 is 円661.33. Overall, Eisai Co has a GF Score™ of 64/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Eisai Co's E10 compare to ZTS and UTHR?
Eisai Co's E10 of 円661.33 can be compared against companies in the Drug Manufacturers industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Drug Manufacturers company?
A good E10 depends on the Drug Manufacturers industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Eisai Co and its competitors. Eisai Co's current E10 is 円661.33. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Eisai Co stock overvalued right now?
Based on GuruFocus' analysis, Eisai Co (TSE:4523) is currently considered Modestly Undervalued. The stock's GF Value™ is 円5,703.17, compared to a current price of 円4,145.00 — trading 27.3% below its estimated fair value. The current E10 is 円661.33. Eisai Co's overall GF Score™ is 64/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Eisai Co (TSE:4523), the current E10 is 円661.33 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Eisai Co (TSE:4523) Overvalued in 2026?

Based on GuruFocus' analysis, Eisai Co stock appears to be undervalued. The current stock price of 円4,145.00 is trading 27.3% below its estimated GF Value™ of 円5,703.17. GuruFocus considers Eisai Co to be Modestly Undervalued.

Key valuation signals for TSE:4523:

  • E10: 円661.33
  • GF Value™: 円5,703.17 vs. price of 円4,145.00 (27.3% below fair value)
  • GF Score™: 64/100 with 7 warning signs

No single metric tells the full story. See the TSE:4523 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Eisai Co Business Description

Address 4-6-10 Koishikawa, Bunkyo-ku, Tokyo, JPN, 112-8088
Eisai Co Ltd is a specialty and generic drug manufacturing company. The company's business consists of research and development, manufacturing, sales, import, and export of pharmaceuticals. The pharmaceutical business is categorized by region, including East Asia & Global South; Europe, Middle East, Africa, Russia, Oceania (EMEA); Americas; China; and Japan. The company also reports a consumer healthcare business for Japan. The vast majority of the company's revenue is derived from its American pharmaceutical business, followed by its Japanese pharmaceuticals segment. The company utilizes licensing strategies in order to expand its research, development, manufacturing, and marketing capabilities.
64GF Score

Get the complete analysis for TSE:4523

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円4,145.00
Price
円5,703.17
GF Value