Santen Pharmaceutical Co (TSE:4536) E10: 円67.07 (As of Mar. 2026)


TSE:4536 Santen Pharmaceutical Co Ltd TSE:4536
76 GF Score
Price 円2,147.50
GF Value 円1,680.35
Valuation Modestly Overvalued
! 6 Warning Signs
View Full Analysis

What is Santen Pharmaceutical Co E10?

Santen Pharmaceutical Co TSE:4536 +0.89% 76 E10 is 円67.07 as of Mar. 2026. GuruFocus rates TSE:4536 with a GF Score™ of 76/100 and a GF Value™ of 円1,680.35 (Modestly Overvalued). The stock has 6 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Santen Pharmaceutical Co's adjusted earnings per share data for the three months ended in Mar. 2026 was 円47.750. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is 円67.07 for the trailing ten years ended in Mar. 2026.

During the past 12 months, Santen Pharmaceutical Co's average E10 Growth Rate was -3.30% per year. During the past 3 years, the average E10 Growth Rate was 4.10% per year. During the past 5 years, the average E10 Growth Rate was 1.70% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

During the past 13 years, the highest 3-Year average E10 Growth Rate of Santen Pharmaceutical Co was 4.10% per year. The lowest was -3.20% per year. And the median was 1.25% per year.

As of today (2026-06-29), Santen Pharmaceutical Co's current stock price is 円2147.50. Santen Pharmaceutical Co's E10 for the quarter that ended in Mar. 2026 was 円67.07. Santen Pharmaceutical Co's Shiller PE Ratio of today is 32.02.

During the past 13 years, the highest Shiller PE Ratio of Santen Pharmaceutical Co was 34.50. The lowest was 14.41. And the median was 25.36.


Santen Pharmaceutical Co  (TSE:4536) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.

Santen Pharmaceutical Co's Shiller P/E Ratio of today is calculated as

Shiller PE Ratio=Share Price/E10
=2147.50/67.07
=32.02

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

During the past 13 years, the highest Shiller P/E Ratio of Santen Pharmaceutical Co was 34.50. The lowest was 14.41. And the median was 25.36.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Santen Pharmaceutical Co E10 Related Terms


Santen Pharmaceutical Co E10 Historical Data

* Premium members only.

The historical data trend for Santen Pharmaceutical Co's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Santen Pharmaceutical Co E10 Chart

Santen Pharmaceutical Co Annual Data
Trend Mar17 Mar18 Mar19 Mar20 Mar21 Mar22 Mar23 Mar24 Mar25 Mar26
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 65.80 59.48 63.14 69.38 67.07

Santen Pharmaceutical Co Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 69.38 69.42 62.17 63.43 67.07

TSE:4536 vs LLY, JNJ, ABBV: E10 Comparison

For the Drug Manufacturers - General subindustry, Santen Pharmaceutical Co's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Santen Pharmaceutical Co Shiller PE Ratio vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Santen Pharmaceutical Co's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Santen Pharmaceutical Co's Shiller PE Ratio falls into.


TSE:4536
76GF Score
Santen Pharmaceutical Co Ltd TSE:4536
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Santen Pharmaceutical Co E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Santen Pharmaceutical Co's adjusted earnings per share data for the three months ended in Mar. 2026 was:

Adj_EPS= Earnings per Share (Diluted) /CPI of Mar. 2026 (Change)*Current CPI (Mar. 2026)
=47.75/112.7000*112.7000
=47.750

Current CPI (Mar. 2026) = 112.7000.

Santen Pharmaceutical Co Quarterly Data

per share eps CPI Adj_EPS
201606 17.610 98.100 20.231
201609 12.480 98.000 14.352
201612 11.400 98.400 13.057
201703 11.230 98.100 12.901
201706 22.120 98.500 25.309
201709 15.300 98.800 17.453
201712 29.600 99.400 33.561
201803 19.400 99.200 22.040
201806 16.790 99.200 19.075
201809 18.440 99.900 20.803
201812 22.030 99.700 24.903
201903 21.170 99.700 23.930
201906 15.990 99.800 18.057
201909 16.860 100.100 18.982
201912 17.860 100.500 20.028
202003 8.300 100.300 9.326
202006 15.460 99.900 17.441
202009 19.040 99.900 21.480
202012 17.940 99.300 20.361
202103 -29.260 99.900 -33.009
202106 18.340 99.500 20.773
202109 17.390 100.100 19.579
202112 12.590 100.100 14.175
202203 19.650 101.100 21.905
202206 16.770 101.800 18.566
202209 -75.560 103.100 -82.596
202212 15.460 104.100 16.737
202303 2.530 104.400 2.731
202306 27.850 105.200 29.836
202309 24.520 106.200 26.021
202312 20.660 106.800 21.801
202403 0.320 107.200 0.336
202406 29.500 108.200 30.727
202409 23.240 108.900 24.051
202412 25.240 110.700 25.696
202503 25.700 111.100 26.070
202506 17.280 111.700 17.435
202509 24.420 112.000 24.573
202512 24.350 113.000 24.285
202603 47.750 112.700 47.750

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of 円67.07 mean?
Santen Pharmaceutical Co (TSE:4536) has a E10 of 円67.07 as of Mar. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Santen Pharmaceutical Co and its competitors.
Is Santen Pharmaceutical Co's E10 too high?
Santen Pharmaceutical Co's current E10 is 円67.07. Overall, Santen Pharmaceutical Co has a GF Score™ of 76/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Santen Pharmaceutical Co's E10 compare to LLY and JNJ?
Santen Pharmaceutical Co's E10 of 円67.07 can be compared against companies in the Drug Manufacturers industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Drug Manufacturers company?
A good E10 depends on the Drug Manufacturers industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Santen Pharmaceutical Co and its competitors. Santen Pharmaceutical Co's current E10 is 円67.07. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Santen Pharmaceutical Co stock overvalued right now?
Based on GuruFocus' analysis, Santen Pharmaceutical Co (TSE:4536) is currently considered Modestly Overvalued. The stock's GF Value™ is 円1,680.35, compared to a current price of 円2,147.50 — trading 27.8% above its estimated fair value. The current E10 is 円67.07. Santen Pharmaceutical Co's overall GF Score™ is 76/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Santen Pharmaceutical Co (TSE:4536), the current E10 is 円67.07 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Santen Pharmaceutical Co (TSE:4536) Overvalued in 2026?

Based on GuruFocus' analysis, Santen Pharmaceutical Co stock appears to be overvalued. The current stock price of 円2,147.50 is trading 27.8% above its estimated GF Value™ of 円1,680.35. GuruFocus considers Santen Pharmaceutical Co to be Modestly Overvalued.

Key valuation signals for TSE:4536:

  • E10: 円67.07
  • GF Value™: 円1,680.35 vs. price of 円2,147.50 (27.8% above fair value)
  • GF Score™: 76/100 with 6 warning signs

No single metric tells the full story. See the TSE:4536 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Santen Pharmaceutical Co Business Description

Other Exchanges SNPHY:USA
Address 4-20 Ofukacho, Grand Front Osaka Tower A, Kita-ku, Osaka Prefecture, Osaka, JPN, 530-8552
Santen Pharmaceutical Co Ltd is a drug manufacturing company that focuses on ophthalmic products. The company provides a wide range of prescription and over-the-counter eye care products, including treatments for glaucoma, dry eye, and allergies. It also develops surgical and diagnostic devices related to eye care.
76GF Score

Get the complete analysis for TSE:4536

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円2,147.50
Price
円1,680.35
GF Value