Kubota Pharmaceutical Holdings Co (TSE:4596) E10: 円-63.14 (As of Mar. 2026)


TSE:4596 Kubota Pharmaceutical Holdings Co Ltd TSE:4596
46 GF Score
Price 円55.00
GF Value 円39.87
Valuation Significantly Overvalued
! 2 Warning Signs
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What is Kubota Pharmaceutical Holdings Co E10?

Kubota Pharmaceutical Holdings Co TSE:4596 46 E10 is 円-63.14 as of Mar. 2026. GuruFocus rates TSE:4596 with a GF Score™ of 46/100 and a GF Value™ of 円39.87 (Significantly Overvalued). The stock has 2 warning signs investors should review.

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. E10 is the average of the inflation adjusted earnings of a company over the past 10 years.

Kubota Pharmaceutical Holdings Co's adjusted earnings per share data for the fiscal year that ended in Dec. 2025 was 円-10.590. Add all the adjusted EPS for the past 10 years together and divide 10 will get our e10, which is 円-63.14 for the trailing ten years ended in Dec. 2025.

Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the E10 growth rate using E10 data.

As of today (2026-06-29), Kubota Pharmaceutical Holdings Co's current stock price is 円 55.00. Kubota Pharmaceutical Holdings Co's E10 for the fiscal year that ended in Dec. 2025 was 円-63.14. Kubota Pharmaceutical Holdings Co's Shiller PE Ratio of today is .


Kubota Pharmaceutical Holdings Co  (TSE:4596) E10 Explanation

If a company grows much fast than inflation, E10 may underestimate the company's earnings power. Shiller PE Ratio can seem to be too high even the actual P/E is low.

For the Shiller P/E, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller P/E is also called PE10.

The Shiller P/E was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.


Be Aware

Shiller PE Ratio works better for cyclical companies. It gives you a better idea on the company's real earnings power.


Kubota Pharmaceutical Holdings Co E10 Related Terms


Kubota Pharmaceutical Holdings Co E10 Historical Data

* Premium members only.

The historical data trend for Kubota Pharmaceutical Holdings Co's E10 can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Kubota Pharmaceutical Holdings Co E10 Chart

Kubota Pharmaceutical Holdings Co Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
E10
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 -67.58 -63.14

Kubota Pharmaceutical Holdings Co Quarterly Data
Dec20 Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Dec24 Mar25 Jun25 Dec25 Mar26
E10 Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -67.58 0.00 0.00 -63.14 0.00

TSE:4596 vs VRTX, REGN, ALNY: E10 Comparison

For the Biotechnology subindustry, Kubota Pharmaceutical Holdings Co's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Kubota Pharmaceutical Holdings Co Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Kubota Pharmaceutical Holdings Co's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Kubota Pharmaceutical Holdings Co's Shiller PE Ratio falls into.


TSE:4596
46GF Score
Kubota Pharmaceutical Holdings Co Ltd TSE:4596
E10 is just one metric. See GF Score™, valuation, warning signs, and more.
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Kubota Pharmaceutical Holdings Co E10 Calculation

E10 is a concept invented by Prof. Robert Shiller, who uses E10 for his Shiller P/E calculation. When we calculate the today's Shiller P/E ratio of a stock, we use today's price divided by E10.

What is E10? How do we calculate E10?

E10 is the average of the inflation adjusted earnings of a company over the past 10 years. Let's use an example to explain.

If we want to calculate the E10 of Wal-Mart (WMT) for Dec. 31, 2010, we need to have the inflation data and the earnings from 2001 through 2010.

We adjusted the earnings of 2001 earnings data with the total inflation from 2001 through 2010 to the equivalent earnings in 2010. If the total inflation from 2001 to 2010 is 40%, and Wal-Mart earned $1 a share in 2001, then the 2001's equivalent earnings in 2010 is $1.4 a share. If Wal-Mart earns $1 again in 2002, and the total inflation from 2002 through 2010 is 35%, then the equivalent 2002 earnings in 2010 is $1.35. So on and so forth, you get the equivalent earnings of past 10 years. Then you add them together and divided the sum by 10 to get E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

For example, Kubota Pharmaceutical Holdings Co's adjusted earnings per share data for the fiscal year that ended in Dec. 2025 was:

Adj_EPS=Earnings per Share (Diluted) /CPI of Dec. 2025 (Change)*Current CPI (Dec. 2025)
=-10.59/113.0000*113.0000
=-10.590

Current CPI (Dec. 2025) = 113.0000.

Kubota Pharmaceutical Holdings Co Annual Data

per_share_eps CPI Adj_EPS
201612 -104.520 98.400 -120.028
201712 -90.850 99.400 -103.280
201812 -78.420 99.700 -88.881
201912 -73.060 100.500 -82.147
202012 -56.900 99.300 -64.750
202112 -57.460 100.100 -64.865
202212 -40.920 104.100 -44.418
202312 -26.790 106.800 -28.345
202412 -23.650 110.700 -24.141
202512 -10.590 113.000 -10.590

Add all the adjusted EPS together and divide 10 will get our e10.

Frequently Asked Questions Learn more about E10 →
What does a E10 of 円-63.14 mean?
Kubota Pharmaceutical Holdings Co (TSE:4596) has a E10 of 円-63.14 as of Mar. 2026. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Kubota Pharmaceutical Holdings Co and its competitors.
Is Kubota Pharmaceutical Holdings Co's E10 too high?
Kubota Pharmaceutical Holdings Co's current E10 is 円-63.14. Overall, Kubota Pharmaceutical Holdings Co has a GF Score™ of 46/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Kubota Pharmaceutical Holdings Co's E10 compare to VRTX and REGN?
Kubota Pharmaceutical Holdings Co's E10 of 円-63.14 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good E10 for a Biotechnology company?
A good E10 depends on the Biotechnology industry context. However, E10 should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high E10 mean?
A high E10 can signal that a stock is expensive relative to its fundamentals. E10 represents the company's inflation-adjusted earnings per share over a 10-year period. View historical data on Kubota Pharmaceutical Holdings Co and its competitors. Kubota Pharmaceutical Holdings Co's current E10 is 円-63.14. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Kubota Pharmaceutical Holdings Co stock overvalued right now?
Based on GuruFocus' analysis, Kubota Pharmaceutical Holdings Co (TSE:4596) is currently considered Significantly Overvalued. The stock's GF Value™ is 円39.87, compared to a current price of 円55.00 — trading 37.9% above its estimated fair value. The current E10 is 円-63.14. Kubota Pharmaceutical Holdings Co's overall GF Score™ is 46/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is E10 calculated?
E10 is calculated from a company's financial statements. For Kubota Pharmaceutical Holdings Co (TSE:4596), the current E10 is 円-63.14 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Kubota Pharmaceutical Holdings Co (TSE:4596) Overvalued in 2026?

Based on GuruFocus' analysis, Kubota Pharmaceutical Holdings Co stock appears to be overvalued. The current stock price of 円55.00 is trading 37.9% above its estimated GF Value™ of 円39.87. GuruFocus considers Kubota Pharmaceutical Holdings Co to be Significantly Overvalued.

Key valuation signals for TSE:4596:

  • E10: 円-63.14
  • GF Value™: 円39.87 vs. price of 円55.00 (37.9% above fair value)
  • GF Score™: 46/100 with 2 warning signs

No single metric tells the full story. See the TSE:4596 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Kubota Pharmaceutical Holdings Co Business Description

Address 1-15-37 Minami-Aoyama, Minato-ku, Tokyo, JPN, 107-0062
Kubota Pharmaceutical Holdings Co Ltd is a Japanese company providing portfolio of drugs and devices to preserve and restore millions of people. It identifies and develops therapeutics to treat the opthalmic disorder and operations incidental or related thereto. Its pipeline products include VCM-Emixustat HCI, Lanosterol and Optogenetics.
46GF Score

Get the complete analysis for TSE:4596

E10 is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

円55.00
Price
円39.87
GF Value