Ultragenyx Pharmaceutical (LTS:0LIF) EBIT: $-536.6 Mil (TTM As of Mar. 2026)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

LTS:0LIF Ultragenyx Pharmaceutical Inc LTS:0LIF
65 GF Score
Price $25.26
GF Value $46.14
Valuation Possible Value Trap
! 5 Warning Signs
View Full Analysis

What is Ultragenyx Pharmaceutical EBIT?

Ultragenyx Pharmaceutical LTS:0LIF +0.46% 65 EBIT is $-536.6 Mil as of Mar. 2026. GuruFocus rates LTS:0LIF with a GF Score™ of 65/100 and a GF Value™ of $46.14 (Possible Value Trap). The stock has 5 warning signs investors should review.

Ultragenyx Pharmaceutical's earnings before interest and taxes (EBIT) for the three months ended in Mar. 2026 was $-163.0 Mil. Its earnings before interest and taxes (EBIT) for the trailing twelve months (TTM) ended in Mar. 2026 was $-536.6 Mil.

EBIT or Operating Income is linked to Return on Capital for both regular definition and Joel Greenblatt's definition. Ultragenyx Pharmaceutical's annualized ROC % for the quarter that ended in Mar. 2026 was -89.24%. Ultragenyx Pharmaceutical's annualized ROC (Joel Greenblatt) % for the quarter that ended in Mar. 2026 was -269.98%.

EBIT is also linked to Joel Greenblatt's definition of earnings yield. Ultragenyx Pharmaceutical's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Mar. 2026 was -27.84%.


Ultragenyx Pharmaceutical  (LTS:0LIF) EBIT Explanation

1. EBIT or Operating Income is linked to Return on Capital for both regular definition and Joel Greenblatt's definition.

Ultragenyx Pharmaceutical's annualized ROC % for the quarter that ended in Mar. 2026 is calculated as:

ROC % (Q: Mar. 2026 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (Q: Dec. 2025 ) + Invested Capital (Q: Mar. 2026 ))/ count )
=-676 * ( 1 - 0% )/( (726 + 789)/ 2 )
=-676/757.5
=-89.24 %

where

Note: The Operating Income data used here is four times the quarterly (Mar. 2026) data.

2. Joel Greenblatt's definition of Return on Capital:

Ultragenyx Pharmaceutical's annualized ROC (Joel Greenblatt) % for the quarter that ended in Mar. 2026 is calculated as:

ROC (Joel Greenblatt) %(Q: Mar. 2026 )
=EBIT/Average of (Net fixed Assets + Net Working Capital)
=EBIT/Average of (Property, Plant and Equipment+Net Working Capital)
     Q: Dec. 2025  Q: Mar. 2026
=EBIT/( ( (Property, Plant and Equipment + Net Working Capital) + (Property, Plant and Equipment + Net Working Capital) )/ count )
=-652/( ( (244 + max(-101, 0)) + (239 + max(-81, 0)) )/ 2 )
=-652/( ( 244 + 239 )/ 2 )
=-652/241.5
=-269.98 %

where Working Capital is:

Working Capital(Q: Dec. 2025 )
=(Accounts Receivable + Total Inventories + Other Current Assets) - (Accounts Payable & Accrued Expense + Defer. Rev. + Other Current Liabilities)
=(158 + 52 + 61) - (239 + 0 + 133)
=-101

Working Capital(Q: Mar. 2026 )
=(Accounts Receivable + Total Inventories + Other Current Assets) - (Accounts Payable & Accrued Expense + Defer. Rev. + Other Current Liabilities)
=(121 + 55 + 68) - (175 + 0 + 150)
=-81

When net working capital is negative, 0 is used.

Note: The EBIT data used here is four times the quarterly (Mar. 2026) EBIT data.

3. It is also linked to Joel Greenblatt's definition of Earnings Yield:

Ultragenyx Pharmaceutical's Earnings Yield (Joel Greenblatt) % for today is calculated as:

Earnings Yield (Joel Greenblatt) %=EBIT (TTM)/Enterprise Value (Q: Mar. 2026 )
=-536.572/1927.659
=-27.84 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Ultragenyx Pharmaceutical EBIT Related Terms


Ultragenyx Pharmaceutical EBIT Historical Data

* Premium members only.

The historical data trend for Ultragenyx Pharmaceutical's EBIT can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ultragenyx Pharmaceutical EBIT Chart

Ultragenyx Pharmaceutical Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EBIT
Get a 7-Day Free Trial Premium Member Only Premium Member Only -423.56 -658.71 -543.00 -504.00 -509.00

Ultragenyx Pharmaceutical Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EBIT Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -136.00 -99.96 -165.39 -108.22 -163.00

LTS:0LIF vs ATAI, QURE, KOD: EBIT Comparison

For the Biotechnology subindustry, Ultragenyx Pharmaceutical's EV-to-EBIT, along with its competitors' market caps and EV-to-EBIT data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Ultragenyx Pharmaceutical EV-to-EBIT vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Ultragenyx Pharmaceutical's EV-to-EBIT distribution charts can be found below:

* The bar in red indicates where Ultragenyx Pharmaceutical's EV-to-EBIT falls into.


LTS:0LIF
65GF Score
Ultragenyx Pharmaceutical Inc LTS:0LIF
EBIT is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Ultragenyx Pharmaceutical EBIT Calculation

EBIT, sometimes also called Earnings Before Interest and Taxes, is a measure of a firm's profit that includes all expenses except interest and income tax expenses. It is the difference between operating revenues and operating expenses. When a firm does not have non-operating income, then Operating Income is sometimes used as a synonym for EBIT and operating profit.

EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-536.6 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EBIT →
What does a EBIT of $-536.6 Mil mean?
Ultragenyx Pharmaceutical (LTS:0LIF) has a EBIT of $-536.6 Mil as of Mar. 2026. Earnings before interest and taxes is the difference between operating revenue and operating expenses. View historical data on Ultragenyx Pharmaceutical.
Is Ultragenyx Pharmaceutical's EBIT too high?
Ultragenyx Pharmaceutical's current EBIT is $-536.6 Mil. Overall, Ultragenyx Pharmaceutical has a GF Score™ of 65/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Ultragenyx Pharmaceutical's EBIT compare to ATAI and QURE?
Ultragenyx Pharmaceutical's EBIT of $-536.6 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EBIT for a Biotechnology company?
A good EBIT depends on the Biotechnology industry context. However, EBIT should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EBIT mean?
A high EBIT can signal that a stock is expensive relative to its fundamentals. Earnings before interest and taxes is the difference between operating revenue and operating expenses. View historical data on Ultragenyx Pharmaceutical. Ultragenyx Pharmaceutical's current EBIT is $-536.6 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Ultragenyx Pharmaceutical stock overvalued right now?
Based on GuruFocus' analysis, Ultragenyx Pharmaceutical (LTS:0LIF) is currently considered Possible Value Trap. The stock's GF Value™ is $46.14, compared to a current price of $25.26 — trading 45.3% below its estimated fair value. The current EBIT is $-536.6 Mil. Ultragenyx Pharmaceutical's overall GF Score™ is 65/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EBIT calculated?
EBIT is calculated from a company's financial statements. For Ultragenyx Pharmaceutical (LTS:0LIF), the current EBIT is $-536.6 Mil as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Ultragenyx Pharmaceutical (LTS:0LIF) Overvalued in 2026?

Based on GuruFocus' analysis, Ultragenyx Pharmaceutical stock appears to be undervalued. The current stock price of $25.26 is trading 45.3% below its estimated GF Value™ of $46.14. GuruFocus considers Ultragenyx Pharmaceutical to be Possible Value Trap.

Key valuation signals for LTS:0LIF:

  • EBIT: $-536.6 Mil
  • GF Value™: $46.14 vs. price of $25.26 (45.3% below fair value)
  • GF Score™: 65/100 with 5 warning signs

No single metric tells the full story. See the LTS:0LIF stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Ultragenyx Pharmaceutical Business Description

Address 60 Leveroni Court, Novato, CA, USA, 94949
Ultragenyx Pharmaceutical Inc is a USA-based biopharmaceutical company. The company identifies, acquires, develops, and commercializes novel products for the treatment of serious, rare, and ultra-rare diseases, with a focus on debilitating genetic conditions. Its medicine portfolio includes Crysvita, Dojolvi, and Mepsevii. Crysvita is indicated for the treatment of X-linked hypophosphatemia (XLH) in adult and pediatric patients aged one year and older. Mepsevii is indicated for pediatric and adult patients for the treatment of Mucopolysaccharidosis VII. The company operates across North America, Latin America, Europe, the Middle East and Africa, and Asia-Pacific, with the majority of its revenue generated from North America.
65GF Score

Get the complete analysis for LTS:0LIF

EBIT is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$25.26
Price
$46.14
GF Value