RARE (Ultragenyx Pharmaceutical) EBITDA Margin %: -113.97% (As of Mar. 2026)

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RARE Ultragenyx Pharmaceutical Inc RARE
70 GF Score
Price $33.22
GF Value $47.30
Valuation Possible Value Trap
! 6 Warning Signs
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What is Ultragenyx Pharmaceutical EBITDA Margin %?

Ultragenyx Pharmaceutical RARE -1.77% 70 EBITDA Margin % is -113.97% as of Mar. 2026. GuruFocus rates RARE with a GF Score™ of 70/100 and a GF Value™ of $47.30 (Possible Value Trap). The stock has 6 warning signs investors should review. Among 939 Biotechnology companies, Ultragenyx Pharmaceutical ranks worse than 50.91% on this metric.

EBITDA Margin % is calculated as EBITDA divided by its Revenue. Ultragenyx Pharmaceutical's EBITDA for the three months ended in Mar. 2026 was $-155.0 Mil. Ultragenyx Pharmaceutical's Revenue for the three months ended in Mar. 2026 was $136.0 Mil. Therefore, Ultragenyx Pharmaceutical's EBITDA margin for the quarter that ended in Mar. 2026 was -113.97%.


Ultragenyx Pharmaceutical  (NAS:RARE) EBITDA Margin % Explanation

EBITDA Margin % is the ratio of EBITDA divided by net sales or Revenue. It is an performance metric measuring company's operating profitability. EBITDA Margin takes depreciation and amortization, interest expense and tax into account, which makes it easy to compare the relative profitability of companies of different sizes in the same industry.


Ultragenyx Pharmaceutical EBITDA Margin % Related Terms


Ultragenyx Pharmaceutical EBITDA Margin % Historical Data

* Premium members only.

The historical data trend for Ultragenyx Pharmaceutical's EBITDA Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ultragenyx Pharmaceutical EBITDA Margin % Chart

Ultragenyx Pharmaceutical Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EBITDA Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -116.77 -176.28 -119.12 -83.57 -70.43

Ultragenyx Pharmaceutical Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EBITDA Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -91.37 -54.87 -98.03 -47.97 -113.97

RARE vs VERA, IRON, QURE: EBITDA Margin % Comparison

For the Biotechnology subindustry, Ultragenyx Pharmaceutical's EBITDA Margin %, along with its competitors' market caps and EBITDA Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Ultragenyx Pharmaceutical EBITDA Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Ultragenyx Pharmaceutical's EBITDA Margin % distribution charts can be found below:

* The bar in red indicates where Ultragenyx Pharmaceutical's EBITDA Margin % falls into.


RARE
70GF Score
Ultragenyx Pharmaceutical Inc RARE
EBITDA Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Ultragenyx Pharmaceutical EBITDA Margin % Calculation

EBITDA margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent.

Ultragenyx Pharmaceutical's EBITDA Margin % for the fiscal year that ended in Dec. 2025 is calculated as

EBITDA Margin %=EBITDA (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-474/673
=-70.43 %

Ultragenyx Pharmaceutical's EBITDA Margin % for the quarter that ended in Mar. 2026 is calculated as

EBITDA Margin %=EBITDA (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-155/136
=-113.97 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EBITDA Margin % →
What does a EBITDA Margin % of -113.97% mean?
Ultragenyx Pharmaceutical (RARE) has a EBITDA Margin % of -113.97% as of Mar. 2026. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on Ultragenyx Pharmaceutical and its competitors. According to the industry distribution chart, Ultragenyx Pharmaceutical ranks #478 out of 939 companies in the Biotechnology industry, placing it in the top 50.9%.
Is Ultragenyx Pharmaceutical's EBITDA Margin % too high?
Ultragenyx Pharmaceutical's current EBITDA Margin % is -113.97%. Based on the distribution chart, Ultragenyx Pharmaceutical ranks #478 out of 939 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Ultragenyx Pharmaceutical has a GF Score™ of 70/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Ultragenyx Pharmaceutical's EBITDA Margin % compare to VERA and IRON?
According to the Biotechnology industry distribution chart, Ultragenyx Pharmaceutical ranks #478 out of 939 companies for EBITDA Margin %. This places Ultragenyx Pharmaceutical in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EBITDA Margin % for a Biotechnology company?
A good EBITDA Margin % depends on the Biotechnology industry context. However, EBITDA Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EBITDA Margin % mean?
A high EBITDA Margin % can signal that a stock is expensive relative to its fundamentals. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on Ultragenyx Pharmaceutical and its competitors. Ultragenyx Pharmaceutical's current EBITDA Margin % is -113.97%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Ultragenyx Pharmaceutical stock overvalued right now?
Based on GuruFocus' analysis, Ultragenyx Pharmaceutical (RARE) is currently considered Possible Value Trap. The stock's GF Value™ is $47.30, compared to a current price of $33.22 — trading 29.8% below its estimated fair value. The current EBITDA Margin % is -113.97%. Ultragenyx Pharmaceutical's overall GF Score™ is 70/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EBITDA Margin % calculated?
EBITDA Margin % is calculated from a company's financial statements. For Ultragenyx Pharmaceutical (RARE), the current EBITDA Margin % is -113.97% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Ultragenyx Pharmaceutical (RARE) Overvalued in 2026?

Based on GuruFocus' analysis, Ultragenyx Pharmaceutical stock appears to be undervalued. The current stock price of $33.22 is trading 29.8% below its estimated GF Value™ of $47.30. GuruFocus considers Ultragenyx Pharmaceutical to be Possible Value Trap.

Key valuation signals for RARE:

  • EBITDA Margin %: -113.97%
  • GF Value™: $47.30 vs. price of $33.22 (29.8% below fair value)
  • GF Score™: 70/100 with 6 warning signs

No single metric tells the full story. See the RARE stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Ultragenyx Pharmaceutical Business Description

Address 60 Leveroni Court, Novato, CA, USA, 94949
Ultragenyx Pharmaceutical Inc is a USA-based biopharmaceutical company. The company identifies, acquires, develops, and commercializes novel products for the treatment of serious, rare, and ultra-rare diseases, with a focus on debilitating genetic conditions. Its medicine portfolio includes Crysvita, Dojolvi, and Mepsevii. Crysvita is indicated for the treatment of X-linked hypophosphatemia (XLH) in adult and pediatric patients aged one year and older. Mepsevii is indicated for pediatric and adult patients for the treatment of Mucopolysaccharidosis VII. The company operates across North America, Latin America, Europe, the Middle East and Africa, and Asia-Pacific, with the majority of its revenue generated from North America.
70GF Score

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EBITDA Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$33.22
Price
$47.30
GF Value