ProQR Therapeutics NV (STU:0PQ) EBITDA Margin %: -637.24% (As of Mar. 2026)

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STU:0PQ ProQR Therapeutics NV STU:0PQ
51 GF Score
Price €1.51
GF Value €1.79
Valuation Modestly Undervalued
! 4 Warning Signs
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What is ProQR Therapeutics NV EBITDA Margin %?

ProQR Therapeutics NV STU:0PQ -4.14% 51 EBITDA Margin % is -637.24% as of Mar. 2026. GuruFocus rates STU:0PQ with a GF Score™ of 51/100 and a GF Value™ of €1.79 (Modestly Undervalued). The stock has 4 warning signs investors should review. Among 940 Biotechnology companies, ProQR Therapeutics NV ranks worse than 66.7% on this metric.

EBITDA Margin % is calculated as EBITDA divided by its Revenue. ProQR Therapeutics NV's EBITDA for the three months ended in Mar. 2026 was €-12.96 Mil. ProQR Therapeutics NV's Revenue for the three months ended in Mar. 2026 was €2.03 Mil. Therefore, ProQR Therapeutics NV's EBITDA margin for the quarter that ended in Mar. 2026 was -637.24%.


ProQR Therapeutics NV  (STU:0PQ) EBITDA Margin % Explanation

EBITDA Margin % is the ratio of EBITDA divided by net sales or Revenue. It is an performance metric measuring company's operating profitability. EBITDA Margin takes depreciation and amortization, interest expense and tax into account, which makes it easy to compare the relative profitability of companies of different sizes in the same industry.


ProQR Therapeutics NV EBITDA Margin % Related Terms


ProQR Therapeutics NV EBITDA Margin % Historical Data

* Premium members only.

The historical data trend for ProQR Therapeutics NV's EBITDA Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

ProQR Therapeutics NV EBITDA Margin % Chart

ProQR Therapeutics NV Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EBITDA Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -4,115.96 -1,570.95 -369.93 -127.60 -242.25

ProQR Therapeutics NV Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EBITDA Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -224.34 -303.22 -368.25 -132.42 -637.24

STU:0PQ vs CRBP, NRXP, CRBU: EBITDA Margin % Comparison

For the Biotechnology subindustry, ProQR Therapeutics NV's EBITDA Margin %, along with its competitors' market caps and EBITDA Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


ProQR Therapeutics NV EBITDA Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, ProQR Therapeutics NV's EBITDA Margin % distribution charts can be found below:

* The bar in red indicates where ProQR Therapeutics NV's EBITDA Margin % falls into.


STU:0PQ
51GF Score
ProQR Therapeutics NV STU:0PQ
EBITDA Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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ProQR Therapeutics NV EBITDA Margin % Calculation

EBITDA margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent.

ProQR Therapeutics NV's EBITDA Margin % for the fiscal year that ended in Dec. 2025 is calculated as

EBITDA Margin %=EBITDA (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-38.533/15.906
=-242.25 %

ProQR Therapeutics NV's EBITDA Margin % for the quarter that ended in Mar. 2026 is calculated as

EBITDA Margin %=EBITDA (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-12.955/2.033
=-637.24 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EBITDA Margin % →
What does a EBITDA Margin % of -637.24% mean?
ProQR Therapeutics NV (STU:0PQ) has a EBITDA Margin % of -637.24% as of Mar. 2026. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on ProQR Therapeutics NV and its competitors. According to the industry distribution chart, ProQR Therapeutics NV ranks #627 out of 940 companies in the Biotechnology industry, placing it in the top 66.7%.
Is ProQR Therapeutics NV's EBITDA Margin % too high?
ProQR Therapeutics NV's current EBITDA Margin % is -637.24%. Based on the distribution chart, ProQR Therapeutics NV ranks #627 out of 940 companies in the Biotechnology industry, which is below the industry midpoint. Overall, ProQR Therapeutics NV has a GF Score™ of 51/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does ProQR Therapeutics NV's EBITDA Margin % compare to CRBP and NRXP?
According to the Biotechnology industry distribution chart, ProQR Therapeutics NV ranks #627 out of 940 companies for EBITDA Margin %. This places ProQR Therapeutics NV in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EBITDA Margin % for a Biotechnology company?
A good EBITDA Margin % depends on the Biotechnology industry context. However, EBITDA Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EBITDA Margin % mean?
A high EBITDA Margin % can signal that a stock is expensive relative to its fundamentals. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on ProQR Therapeutics NV and its competitors. ProQR Therapeutics NV's current EBITDA Margin % is -637.24%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is ProQR Therapeutics NV stock overvalued right now?
Based on GuruFocus' analysis, ProQR Therapeutics NV (STU:0PQ) is currently considered Modestly Undervalued. The stock's GF Value™ is €1.79, compared to a current price of €1.51 — trading 15.9% below its estimated fair value. The current EBITDA Margin % is -637.24%. ProQR Therapeutics NV's overall GF Score™ is 51/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EBITDA Margin % calculated?
EBITDA Margin % is calculated from a company's financial statements. For ProQR Therapeutics NV (STU:0PQ), the current EBITDA Margin % is -637.24% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is ProQR Therapeutics NV (STU:0PQ) Overvalued in 2026?

Based on GuruFocus' analysis, ProQR Therapeutics NV stock appears to be undervalued. The current stock price of €1.51 is trading 15.9% below its estimated GF Value™ of €1.79. GuruFocus considers ProQR Therapeutics NV to be Modestly Undervalued.

Key valuation signals for STU:0PQ:

  • EBITDA Margin %: -637.24%
  • GF Value™: €1.79 vs. price of €1.51 (15.9% below fair value)
  • GF Score™: 51/100 with 4 warning signs

No single metric tells the full story. See the STU:0PQ stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


ProQR Therapeutics NV Business Description

Other Exchanges PRQR:USA
Address Zernikedreef 9, Leiden, ZH, NLD, 2333 CK
ProQR Therapeutics NV is a biopharmaceutical company. It discovers and develops RNA therapeutics for patients with severe genetic rare diseases such as cystic fibrosis, Leber congenital amaurosis type 10, and dystrophic epidermolysis bullosa. The only reportable segment of the company is the discovery and development of different, RNA-based therapeutics. Geographically, the company operates in United States.
51GF Score

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EBITDA Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€1.51
Price
€1.79
GF Value