Xenetic Biosciences (STU:3XB0) EBITDA Margin %: -62.18% (As of Mar. 2026)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

STU:3XB0 Xenetic Biosciences Inc STU:3XB0
78 GF Score
Price €3.10
GF Value €4.66
! 2 Warning Signs
View Full Analysis

What is Xenetic Biosciences EBITDA Margin %?

Xenetic Biosciences STU:3XB0 78 EBITDA Margin % is -62.18% as of Mar. 2026. GuruFocus rates STU:3XB0 with a GF Score™ of 78/100 and a GF Value™ of €4.66. The stock has 2 warning signs investors should review. Among 940 Biotechnology companies, Xenetic Biosciences ranks worse than 51.06% on this metric.

EBITDA Margin % is calculated as EBITDA divided by its Revenue. Xenetic Biosciences's EBITDA for the three months ended in Mar. 2026 was €-0.43 Mil. Xenetic Biosciences's Revenue for the three months ended in Mar. 2026 was €0.70 Mil. Therefore, Xenetic Biosciences's EBITDA margin for the quarter that ended in Mar. 2026 was -62.18%.


Xenetic Biosciences  (STU:3XB0) EBITDA Margin % Explanation

EBITDA Margin % is the ratio of EBITDA divided by net sales or Revenue. It is an performance metric measuring company's operating profitability. EBITDA Margin takes depreciation and amortization, interest expense and tax into account, which makes it easy to compare the relative profitability of companies of different sizes in the same industry.


Xenetic Biosciences EBITDA Margin % Related Terms


Xenetic Biosciences EBITDA Margin % Historical Data

* Premium members only.

The historical data trend for Xenetic Biosciences's EBITDA Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Xenetic Biosciences EBITDA Margin % Chart

Xenetic Biosciences Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EBITDA Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -492.11 -392.05 -177.80 -168.13 -95.24

Xenetic Biosciences Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EBITDA Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -158.65 -122.66 -53.03 -81.35 -62.18

STU:3XB0 vs ACXP, SILO, GOVX: EBITDA Margin % Comparison

For the Biotechnology subindustry, Xenetic Biosciences's EBITDA Margin %, along with its competitors' market caps and EBITDA Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Xenetic Biosciences EBITDA Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Xenetic Biosciences's EBITDA Margin % distribution charts can be found below:

* The bar in red indicates where Xenetic Biosciences's EBITDA Margin % falls into.


STU:3XB0
78GF Score
Xenetic Biosciences Inc STU:3XB0
EBITDA Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Xenetic Biosciences EBITDA Margin % Calculation

EBITDA margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent.

Xenetic Biosciences's EBITDA Margin % for the fiscal year that ended in Dec. 2025 is calculated as

EBITDA Margin %=EBITDA (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-2.421/2.542
=-95.24 %

Xenetic Biosciences's EBITDA Margin % for the quarter that ended in Mar. 2026 is calculated as

EBITDA Margin %=EBITDA (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-0.434/0.698
=-62.18 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EBITDA Margin % →
What does a EBITDA Margin % of -62.18% mean?
Xenetic Biosciences (STU:3XB0) has a EBITDA Margin % of -62.18% as of Mar. 2026. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on Xenetic Biosciences and its competitors. According to the industry distribution chart, Xenetic Biosciences ranks #480 out of 940 companies in the Biotechnology industry, placing it in the top 51.1%.
Is Xenetic Biosciences' EBITDA Margin % too high?
Xenetic Biosciences' current EBITDA Margin % is -62.18%. Based on the distribution chart, Xenetic Biosciences ranks #480 out of 940 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Xenetic Biosciences has a GF Score™ of 78/100, reflecting its overall financial health beyond just this single metric.
How does Xenetic Biosciences' EBITDA Margin % compare to ACXP and SILO?
According to the Biotechnology industry distribution chart, Xenetic Biosciences ranks #480 out of 940 companies for EBITDA Margin %. This places Xenetic Biosciences in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EBITDA Margin % for a Biotechnology company?
A good EBITDA Margin % depends on the Biotechnology industry context. However, EBITDA Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EBITDA Margin % mean?
A high EBITDA Margin % can signal that a stock is expensive relative to its fundamentals. EBITDA Margin is the ratio of EBITDA divided by net sales or Revenue, usually presented in percent. View historical data on Xenetic Biosciences and its competitors. Xenetic Biosciences's current EBITDA Margin % is -62.18%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Xenetic Biosciences stock overvalued right now?
Xenetic Biosciences (STU:3XB0) has a current EBITDA Margin % of -62.18%. The stock's GF Value™ is €4.66, compared to a current price of €3.10 — trading 33.5% below its estimated fair value. The current EBITDA Margin % is -62.18%. Xenetic Biosciences' overall GF Score™ is 78/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EBITDA Margin % calculated?
EBITDA Margin % is calculated from a company's financial statements. For Xenetic Biosciences (STU:3XB0), the current EBITDA Margin % is -62.18% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Xenetic Biosciences (STU:3XB0) Overvalued in 2026?

Based on GuruFocus' analysis, Xenetic Biosciences stock appears to be undervalued. The current stock price of €3.10 is trading 33.5% below its estimated GF Value™ of €4.66.

Key valuation signals for STU:3XB0:

  • EBITDA Margin %: -62.18%
  • GF Value™: €4.66 vs. price of €3.10 (33.5% below fair value)
  • GF Score™: 78/100 with 2 warning signs

No single metric tells the full story. See the STU:3XB0 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Xenetic Biosciences Business Description

Other Exchanges XBIO:USA
Address 945 Concord Street, Framingham, MA, USA, 01701
Xenetic Biosciences Inc is a biopharmaceutical company focused on progressing XCART, a personalized CAR T platform technology engineered to target patient-specific tumor neoantigens. The Company is initially advancing cell-based therapeutics targeting the unique B-cell receptor on the surface of an individual patient’s malignant tumor cells for the treatment of B-cell lymphomas. XCART has the potential to fuel a robust pipeline of therapeutic assets targeting high-value oncology indications. Additionally, Xenetic is leveraging PolyXen™, its proprietary drug delivery platform, by partnering with biotechnology and pharmaceutical companies. PolyXen™ has demonstrated its ability to improve the half-life and other pharmacological properties of next-generation biologic drugs. The Company has an exclusive license agreement with Takeda Pharmaceuticals Co. Ltd. in the field of coagulation disorders and expects to earn royalty payments under this agreement.
78GF Score

Get the complete analysis for STU:3XB0

EBITDA Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€3.10
Price
€4.66
GF Value