PYC Therapeutics (ASX:PYC) EBITDA: A$-47.60 Mil (TTM As of Dec. 2025)


ASX:PYC PYC Therapeutics Ltd ASX:PYC
35 GF Score
Price A$1.54
! 1 Warning Sign
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What is PYC Therapeutics EBITDA?

PYC Therapeutics ASX:PYC 35 EBITDA is A$-47.60 Mil as of Dec. 2025. GuruFocus rates ASX:PYC with a GF Score™ of 35/100. The stock has 1 warning sign investors should review.

PYC Therapeutics's EBITDA for the six months ended in Dec. 2025 was A$-22.79 Mil. Its EBITDA for the trailing twelve months (TTM) ended in Dec. 2025 was A$-47.60 Mil.

During the past 3 years, the average EBITDA Growth Rate was -55.40% per year. During the past 5 years, the average EBITDA Growth Rate was -37.80% per year. During the past 10 years, the average EBITDA Growth Rate was -26.20% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the EBITDA Growth Rate using EBITDA data.

During the past 13 years, the highest 3-Year average EBITDA Growth Rate of PYC Therapeutics was 13.60% per year. The lowest was -55.40% per year. And the median was -9.95% per year.

PYC Therapeutics's EBITDA per Share for the six months ended in Dec. 2025 was A$-0.04. Its EBITDA per share for the trailing twelve months (TTM) ended in Dec. 2025 was A$-0.08.

During the past 3 years, the average EBITDA per Share Growth Rate was -34.80% per year. During the past 5 years, the average EBITDA per Share Growth Rate was -23.80% per year. During the past 10 years, the average EBITDA per Share Growth Rate was -13.00% per year. Please click Growth Rate Calculation Example (GuruFocus) to see how GuruFocus calculates Wal-Mart Stores Inc (WMT)'s revenue growth rate. You can apply the same method to get the EBITDA per share growth rate using EBITDA per Share data.

During the past 13 years, the highest 3-Year average EBITDA per Share Growth Rate of PYC Therapeutics was 32.00% per year. The lowest was -34.80% per year. And the median was 9.10% per year.

PYC Therapeutics  (ASX:PYC) EBITDA Explanation

EBITDA is a cash flow measure that ignores changes in working capital. EBITDA minus Depreciation, and Amortization (DA) equals Operating Income. Operating Income is profit before interest and taxes. Of course, Interest and taxes need to be paid.

While depreciation and amortization expenses do not need to be paid in cash, assets - especially tangible assets - do need to be replaced over time. EBITDA is not a measure of profit in any sense. EBITDA is a measure of cash generation by a business where the uses of that cash may be more or less discretionary depending on the nature of the business.

The EBITDA of a TV station is largely discretionary. Owners may use much of the EBITDA generated by a TV station as they see fit. The EBITDA of a railroad is largely non-discretionary. Owners must use much of the EBITDA generated by a railroad to replace the physical assets of the railroad or the business will literally fall apart over time.

EBITDA can be thought of as the cash a business generates that is available to:

Add more inventory
Add more receivables
Replace property, plant, and equipment
Add more property, plant, and equipment
Pay interest
Pay taxes
And finally: pay owners

EBITDA is widely used in financial analysis because Depreciation and Amortization are not present day cash expenses.. Depreciation and amortization are the spreading out of the costs of assets over the time in which those assets provide benefits. Today's depreciation and amortization expenses relate to assets bought in the past. The assets being expensed may or may not need to be replaced in the future. And the cost to replace the assets may be more or less than it was in the past. For this reason, the depreciation and amortization expenses a company records in the present year may have no relationship to the actual cash costs needed to maintain its assets in future years.

A company's depreciation expense depends on both its expectations about the assets it owns and its choice of accounting methods. Two companies owning identical assets may have different depreciation expenses because they have different expectations about the useful lives of those assets and because they make different accounting choices.

Analysts use EBITDA to remove this element of personal choice from a company's accounting statements. The use of EBITDA is an attempt to make the results of different companies more comparable and uniform.


Be Aware

Although depreciation is not a cash cost it is a real business cost because the company has to pay for the fixed assets when they purchase them. Both Warren Buffett and Charlie Munger hate the idea of EBITDA because in this calculation, depreciation is not counted as an expense.

EBITDA over Revenue is a good metric for comparing the operating efficiencies between companies because EBITDA is less vulnerable to companies' accounting choices. For this reason, EBITDA is used in ranking the Predictability of Companies. Also Price-to-EBITDA is sometimes used in valuations.


PYC Therapeutics EBITDA Related Terms


PYC Therapeutics EBITDA Historical Data

* Premium members only.

The historical data trend for PYC Therapeutics's EBITDA can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

PYC Therapeutics EBITDA Chart

PYC Therapeutics Annual Data
Trend Jun16 Jun17 Jun18 Jun19 Jun20 Jun21 Jun22 Jun23 Jun24 Jun25
EBITDA
Get a 7-Day Free Trial Premium Member Only Premium Member Only -17.97 -13.42 -22.78 -37.46 -50.35

PYC Therapeutics Semi-Annual Data
Jun16 Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
EBITDA Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -14.88 -22.58 -25.54 -24.81 -22.79

ASX:PYC vs VRTX, REGN, ALNY: EBITDA Comparison

For the Biotechnology subindustry, PYC Therapeutics's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


PYC Therapeutics EV-to-EBITDA vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, PYC Therapeutics's EV-to-EBITDA distribution charts can be found below:

* The bar in red indicates where PYC Therapeutics's EV-to-EBITDA falls into.


ASX:PYC
35GF Score
PYC Therapeutics Ltd ASX:PYC
EBITDA is just one metric. See GF Score™, valuation, warning signs, and more.
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Earnings Before Interest, Taxes, Depreciation, and Amortization (EBITDA) is what the company earns before it expenses interest, taxes, depreciation and amortization.

PYC Therapeutics's EBITDA for the fiscal year that ended in Jun. 2025 is calculated as

PYC Therapeutics's EBITDA was directly provided by GuruFocus' data source Morningstar. For the fiscal year ended in Jun. 2025, PYC Therapeutics's EBITDA was A$-50.35 Mil.

PYC Therapeutics's EBITDA for the quarter that ended in Dec. 2025 is calculated as

PYC Therapeutics's EBITDA was directly provided by GuruFocus' data source Morningstar. For the quarter ended in Dec. 2025, PYC Therapeutics's EBITDA was A$-22.79 Mil.

EBITDA for the trailing twelve months (TTM) ended in Dec. 2025 adds up the semi-annually data reported by the company within the most recent 12 months, which was A$-47.60 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Sometimes companies may have already deducted Depreciation and Amortization from Gross Profit. In this case Depreciation and Amortization needs to be added back when calculating EBITDA.

Frequently Asked Questions Learn more about EBITDA →
What does a EBITDA of A$-47.60 Mil mean?
PYC Therapeutics (ASX:PYC) has a EBITDA of A$-47.60 Mil as of Dec. 2025. Ebitda is the difference between operating revenue and operating expenses not including depreciation and amortization. View historical data on PYC Therapeutics.
Is PYC Therapeutics' EBITDA too high?
PYC Therapeutics' current EBITDA is A$-47.60 Mil. Overall, PYC Therapeutics has a GF Score™ of 35/100, reflecting its overall financial health beyond just this single metric.
How does PYC Therapeutics' EBITDA compare to VRTX and REGN?
PYC Therapeutics' EBITDA of A$-47.60 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EBITDA for a Biotechnology company?
A good EBITDA depends on the Biotechnology industry context. However, EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EBITDA mean?
A high EBITDA can signal that a stock is expensive relative to its fundamentals. Ebitda is the difference between operating revenue and operating expenses not including depreciation and amortization. View historical data on PYC Therapeutics. PYC Therapeutics's current EBITDA is A$-47.60 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is PYC Therapeutics stock overvalued right now?
PYC Therapeutics (ASX:PYC) has a current EBITDA of A$-47.60 Mil. The current EBITDA is A$-47.60 Mil. PYC Therapeutics' overall GF Score™ is 35/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EBITDA calculated?
EBITDA is calculated from a company's financial statements. For PYC Therapeutics (ASX:PYC), the current EBITDA is A$-47.60 Mil as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

PYC Therapeutics Business Description

Other Exchanges PYCXF:USA
Address 6 Verdun Street, Harry Perkins Institute of Medical Research, Nedlands, Perth, WA, AUS, 6009
PYC Therapeutics Ltd is an RNA therapeutics drug development company, leveraging a proprietary delivery platform to solve the challenges in RNA therapeutics - safe and effective delivery of the drug inside the cell. The company's principal business activity is of of drug development and progressing the company's drug pipeline through preclinical and clinical development. Geographically, it operates only in Australia.
35GF Score

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EBITDA is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

A$1.54
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