AVTX (Avalo Therapeutics) EV-to-EBIT: -11.03 (As of Jul. 23, 2026)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

AVTX Avalo Therapeutics Inc AVTX
23 GF Score
Price $18.04
GF Value $0.03
Valuation Significantly Overvalued
! 5 Warning Signs
View Full Analysis

What is Avalo Therapeutics EV-to-EBIT?

Avalo Therapeutics AVTX -0.61% 23 EV-to-EBIT is -11.03 as of Jul. 23, 2026. GuruFocus rates AVTX with a GF Score™ of 23/100 and a GF Value™ of $0.03 (Significantly Overvalued). The stock has 5 warning signs investors should review. Among 374 Biotechnology companies, Avalo Therapeutics ranks worse than 267379.41% on this metric.

EV-to-EBIT is calculated as Enterprise Value divided by its EBIT. As of today, Avalo Therapeutics's Enterprise Value is $872.71 Mil. Avalo Therapeutics's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was $-79.16 Mil. Therefore, Avalo Therapeutics's EV-to-EBIT for today is -11.03.

The historical rank and industry rank for Avalo Therapeutics's EV-to-EBIT or its related term are showing as below:

AVTX' s EV-to-EBIT Range Over the Past 10 Years
Min: -16.99   Med: -1.16   Max: 16.57
Current: -11.03

During the past 13 years, the highest EV-to-EBIT of Avalo Therapeutics was 16.57. The lowest was -16.99. And the median was -1.16.

AVTX's EV-to-EBIT is ranked worse than
100% of 374 companies
in the Biotechnology industry
Industry Median: 13.035 vs AVTX: -11.03

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %. Avalo Therapeutics's Enterprise Value for the quarter that ended in Mar. 2026 was $286.18 Mil. Avalo Therapeutics's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was $-79.16 Mil. Avalo Therapeutics's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Mar. 2026 was -27.66%.


Avalo Therapeutics  (NAS:AVTX) EV-to-EBIT Explanation

This is a more accurate valuation of companies' operation because it considers the debt and cash on its balance sheet, and non-operating items such as interest payment, tax, and one-time items are not included in the Operating Income.

Joel Greenblatt calls the inversion of this ratio Earnings Yield (Joel Greenblatt) %.

Avalo Therapeutics's Earnings Yield (Joel Greenblatt) % for the quarter that ended in Mar. 2026 is calculated as:

Earnings Yield (Joel Greenblatt) % (Q: Mar. 2026 ) =EBIT / Enterprise Value (Q: Mar. 2026 )
=-79.157/286.18034
=-27.66 %

Avalo Therapeutics's Enterprise Value for the quarter that ended in Mar. 2026 was $286.18 Mil.
Avalo Therapeutics's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-79.16 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Avalo Therapeutics EV-to-EBIT Related Terms


Avalo Therapeutics EV-to-EBIT Historical Data

* Premium members only.

The historical data trend for Avalo Therapeutics's EV-to-EBIT can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Avalo Therapeutics EV-to-EBIT Chart

Avalo Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-EBIT
Get a 7-Day Free Trial Premium Member Only Premium Member Only -2.07 -1.44 -0.02 1.37 -3.27

Avalo Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EV-to-EBIT Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.75 0.97 -1.74 -3.27 -3.62

AVTX vs SANA, ANRO, REPL: EV-to-EBIT Comparison

For the Biotechnology subindustry, Avalo Therapeutics's EV-to-EBIT, along with its competitors' market caps and EV-to-EBIT data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Avalo Therapeutics EV-to-EBIT vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Avalo Therapeutics's EV-to-EBIT distribution charts can be found below:

* The bar in red indicates where Avalo Therapeutics's EV-to-EBIT falls into.


AVTX
23GF Score
Avalo Therapeutics Inc AVTX
EV-to-EBIT is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Avalo Therapeutics EV-to-EBIT Calculation

Avalo Therapeutics's EV-to-EBIT for today is calculated as:

EV-to-EBIT=Enterprise Value (Today)/EBIT (TTM)
=872.709/-79.157
=-11.03

Avalo Therapeutics's current Enterprise Value is $872.71 Mil.
Avalo Therapeutics's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-79.16 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBIT →
What does a EV-to-EBIT of -11.03 mean?
Avalo Therapeutics (AVTX) has a EV-to-EBIT of -11.03 as of Jul. 23, 2026. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on Avalo Therapeutics and its competitors. According to the industry distribution chart, Avalo Therapeutics ranks #999999 out of 374 companies in the Biotechnology industry.
Is Avalo Therapeutics' EV-to-EBIT too high?
Avalo Therapeutics' current EV-to-EBIT is -11.03. Based on the distribution chart, Avalo Therapeutics ranks #999999 out of 374 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Avalo Therapeutics has a GF Score™ of 23/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Avalo Therapeutics' EV-to-EBIT compare to SANA and ANRO?
According to the Biotechnology industry distribution chart, Avalo Therapeutics ranks #999999 out of 374 companies for EV-to-EBIT. This places Avalo Therapeutics in the lower half of its industry. The industry median EV-to-EBIT is 13.04. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBIT for a Biotechnology company?
The median EV-to-EBIT among Biotechnology companies is 13.04, based on 374 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBIT significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBIT should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBIT mean?
A high EV-to-EBIT can signal that a stock is expensive relative to its fundamentals. EV to EBIT ratio is the inverse of Joel Greenblatt's earnings yield definition. View historical data on Avalo Therapeutics and its competitors. For the Biotechnology industry, the median EV-to-EBIT is 13.04 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Avalo Therapeutics's current EV-to-EBIT is -11.03. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Avalo Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Avalo Therapeutics (AVTX) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.03, compared to a current price of $18.04 — trading 60033.3% above its estimated fair value. The current EV-to-EBIT is -11.03. Avalo Therapeutics' overall GF Score™ is 23/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBIT calculated?
EV-to-EBIT is calculated from a company's financial statements. For Avalo Therapeutics (AVTX), the current EV-to-EBIT is -11.03 as of Jul. 23, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Avalo Therapeutics (AVTX) Overvalued in 2026?

Based on GuruFocus' analysis, Avalo Therapeutics stock appears to be overvalued. The current stock price of $18.04 is trading 60033.3% above its estimated GF Value™ of $0.03. GuruFocus considers Avalo Therapeutics to be Significantly Overvalued.

Key valuation signals for AVTX:

  • EV-to-EBIT: -11.03
  • GF Value™: $0.03 vs. price of $18.04 (60033.3% above fair value)
  • GF Score™: 23/100 with 5 warning signs

No single metric tells the full story. See the AVTX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Avalo Therapeutics Business Description

Other Exchanges C6K0:Germany
Address 1500 Liberty Ridge Drive, Suite 321, Wayne, PA, USA, 19087
Avalo Therapeutics Inc is a clinical stage biotechnology company fully dedicated to developing IL-1B-based treatments for immune-mediated inflammatory diseases. The company's asset is Abdakibart (AVTX-009) an anti-IL-1B monoclonal antibody ("mAb"), targeting inflammatory diseases. Avalos pipeline also includes quisovalimab (anti-LIGHT mAb) and AVTX-008 (BTLA agonist fusion protein), AVTX-006 and AVTX-913.
23GF Score

Get the complete analysis for AVTX

EV-to-EBIT is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$18.04
Price
$0.03
GF Value