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BillionToOneBLLN -0.25%15 EV-to-EBITDA is 81.19 as of Aug. 21, 2026, which is 42% below its 10-year median of 141.12. GuruFocus rates BLLN with a GF Score™ of 15/100. The stock has 4 warning signs investors should review. Among 117 Medical Diagnostics & Research companies, BillionToOne ranks worse than 97.44% on this metric.
EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, BillionToOne's enterprise value is $4,079.5 Mil.
BillionToOne's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 was $50.2 Mil. Therefore, BillionToOne's EV-to-EBITDA for today is 81.19.
The historical rank and industry rank for BillionToOne's EV-to-EBITDA or its related term are showing as below:
BLLN'
s EV-to-EBITDA Range Over the Past 10 Years
Min: 81.05 Med: 141.12 Max: 2743.84
Current: 81.19
During the past 3 years, the highest EV-to-EBITDA of BillionToOne was 2743.84. The lowest was 81.05. And the median was 141.12.
BLLN's EV-to-EBITDA is ranked worse than 97.44% of 117
companies
in the Medical Diagnostics & Research industry
Industry Median: 17.13
vs BLLN: 81.19
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
BillionToOne's PE Ratio (TTM) for today is calculated as:
BillionToOne's share price for today is $95.05.
BillionToOne's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $0.634.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
The historical data trend for BillionToOne's EV-to-EBITDA can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Diagnostics & Research subindustry, BillionToOne's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
BillionToOne EV-to-EBITDA vs Medical Diagnostics & Research Industry
For the Medical Diagnostics & Research industry and Healthcare sector, BillionToOne's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where BillionToOne's EV-to-EBITDA falls into.
BillionToOne's current Enterprise Value is $4,079.5 Mil.
BillionToOne's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $50.2 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
BillionToOne (BLLN) has a EV-to-EBITDA of 81.19 as of Aug. 21, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on BillionToOne. This is 42% below median its historical median of 141.12. Over the past decade, BillionToOne's EV-to-EBITDA has ranged from 81.05 to 2,743.84. According to the industry distribution chart, BillionToOne ranks #114 out of 117 companies in the Medical Diagnostics & Research industry, placing it in the top 97.4%.
Is BillionToOne's EV-to-EBITDA too high?
BillionToOne's current EV-to-EBITDA of 81.19 is 42% below median its 10-year median of 141.12. Over the past 10 years, this metric has ranged from a low of 81.05 to a high of 2,743.84. The Medical Diagnostics & Research industry median EV-to-EBITDA is 17.13. BillionToOne's value of 81.19 is 374% above this industry median. Based on the distribution chart, BillionToOne ranks #114 out of 117 companies in the Medical Diagnostics & Research industry, which is in the bottom quartile relative to peers. Overall, BillionToOne has a GF Score™ of 15/100, reflecting its overall financial health beyond just this single metric.
How does BillionToOne's EV-to-EBITDA compare to TWST and SHC?
According to the Medical Diagnostics & Research industry distribution chart, BillionToOne ranks #114 out of 117 companies for EV-to-EBITDA. This places BillionToOne in the lower half of its industry. The industry median EV-to-EBITDA is 17.13. BillionToOne's value of 81.19 is 374% above this benchmark. Historically, BillionToOne's own EV-to-EBITDA has ranged from 81.05 to 2,743.84 over the past decade. While the company's 10-year median is 141.12 vs. the industry median of 17.13, BillionToOne has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Medical Diagnostics & Research company?
The median EV-to-EBITDA among Medical Diagnostics & Research companies is 17.13, based on 117 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. BillionToOne's current EV-to-EBITDA of 81.19 is 374% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on BillionToOne. For the Medical Diagnostics & Research industry, the median EV-to-EBITDA is 17.13 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. BillionToOne's current EV-to-EBITDA is 81.19, which is 42% below median its own 10-year median of 141.12. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is BillionToOne stock overvalued right now?
BillionToOne (BLLN) has a current EV-to-EBITDA of 81.19. The current EV-to-EBITDA is 81.19, which is 42% below median its 10-year median of 141.12 and 374% above the Medical Diagnostics & Research industry median of 17.13. BillionToOne's overall GF Score™ is 15/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For BillionToOne (BLLN), the current EV-to-EBITDA is 81.19 as of Aug. 21, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
BillionToOne Inc is a molecular diagnostics company. It offers a portfolio of ultrasensitive tests covering prenatal genetic testing, cancer therapy selection, and response monitoring, which are based on its Quantitative Counting Templates (QCT) molecular counting platform. The company's product portfolio comprises UNITY, a portfolio of prenatal testing products that can conduct fetal risk analysis without requiring a paternal sample; Northstar Select, a ultrasensitive liquid biopsy test that provides insights into appropriate therapies for stage III or IV cancer patients; and Northstar Response, a tissue-free, pan-cancer, liquid biopsy test that measures several genomic loci uniquely methylated in cancer to provide insight into dynamic changes in therapy response.
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