CLDX (Celldex Therapeutics) EV-to-EBITDA: -8.33 (As of Jul. 15, 2026)

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CLDX Celldex Therapeutics Inc CLDX
57 GF Score
Price $38.17
GF Value $7.52
Valuation Significantly Overvalued
! 8 Warning Signs
View Full Analysis

What is Celldex Therapeutics EV-to-EBITDA?

Celldex Therapeutics CLDX -0.93% 57 EV-to-EBITDA is -8.33 as of Jul. 15, 2026. GuruFocus rates CLDX with a GF Score™ of 57/100 and a GF Value™ of $7.52 (Significantly Overvalued). The stock has 8 warning signs investors should review. Among 398 Biotechnology companies, Celldex Therapeutics ranks worse than 251256.03% on this metric.

EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Celldex Therapeutics's enterprise value is $2,546.49 Mil. Celldex Therapeutics's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 was $-305.70 Mil. Therefore, Celldex Therapeutics's EV-to-EBITDA for today is -8.33.

The historical rank and industry rank for Celldex Therapeutics's EV-to-EBITDA or its related term are showing as below:

CLDX' s EV-to-EBITDA Range Over the Past 10 Years
Min: -40.42   Med: -4.49   Max: 0.91
Current: -8.33

During the past 13 years, the highest EV-to-EBITDA of Celldex Therapeutics was 0.91. The lowest was -40.42. And the median was -4.49.

CLDX's EV-to-EBITDA is ranked worse than
100% of 398 companies
in the Biotechnology industry
Industry Median: 12.62 vs CLDX: -8.33

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.

As of today (2026-07-15), Celldex Therapeutics's stock price is $38.17. Celldex Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 was $-4.260. Therefore, Celldex Therapeutics's PE Ratio (TTM) for today is At Loss.

The "classic" EV-to-EBITDA is much better in capturing debt and net cash than the PE Ratio (TTM).


Celldex Therapeutics  (NAS:CLDX) EV-to-EBITDA Explanation

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

Celldex Therapeutics's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=38.17/-4.260
=At Loss

Celldex Therapeutics's share price for today is $38.17.
Celldex Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-4.260.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).

Please read Which price ratio outperforms the enterprise multiple?


Celldex Therapeutics EV-to-EBITDA Related Terms


Celldex Therapeutics EV-to-EBITDA Historical Data

* Premium members only.

The historical data trend for Celldex Therapeutics's EV-to-EBITDA can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Celldex Therapeutics EV-to-EBITDA Chart

Celldex Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-EBITDA
Get a 7-Day Free Trial Premium Member Only Premium Member Only -21.19 -17.30 -12.91 -4.98 -4.55

Celldex Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EV-to-EBITDA Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -2.50 -3.13 -4.50 -4.55 -5.44

CLDX vs TARS, KLRA, IRON: EV-to-EBITDA Comparison

For the Biotechnology subindustry, Celldex Therapeutics's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Celldex Therapeutics EV-to-EBITDA vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Celldex Therapeutics's EV-to-EBITDA distribution charts can be found below:

* The bar in red indicates where Celldex Therapeutics's EV-to-EBITDA falls into.


CLDX
57GF Score
Celldex Therapeutics Inc CLDX
EV-to-EBITDA is just one metric. See GF Score™, valuation, warning signs, and more.
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Celldex Therapeutics EV-to-EBITDA Calculation

Celldex Therapeutics's EV-to-EBITDA for today is calculated as:

EV-to-EBITDA=Enterprise Value (Today)/EBITDA (TTM)
=2546.492/-305.695
=-8.33

Celldex Therapeutics's current Enterprise Value is $2,546.49 Mil.
Celldex Therapeutics's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-305.70 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBITDA →
What does a EV-to-EBITDA of -8.33 mean?
Celldex Therapeutics (CLDX) has a EV-to-EBITDA of -8.33 as of Jul. 15, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Celldex Therapeutics. According to the industry distribution chart, Celldex Therapeutics ranks #999999 out of 398 companies in the Biotechnology industry.
Is Celldex Therapeutics' EV-to-EBITDA too high?
Celldex Therapeutics' current EV-to-EBITDA is -8.33. Based on the distribution chart, Celldex Therapeutics ranks #999999 out of 398 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Celldex Therapeutics has a GF Score™ of 57/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Celldex Therapeutics' EV-to-EBITDA compare to TARS and KLRA?
According to the Biotechnology industry distribution chart, Celldex Therapeutics ranks #999999 out of 398 companies for EV-to-EBITDA. This places Celldex Therapeutics in the lower half of its industry. The industry median EV-to-EBITDA is 12.62. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 12.62, based on 398 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Celldex Therapeutics. For the Biotechnology industry, the median EV-to-EBITDA is 12.62 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Celldex Therapeutics's current EV-to-EBITDA is -8.33. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Celldex Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Celldex Therapeutics (CLDX) is currently considered Significantly Overvalued. The stock's GF Value™ is $7.52, compared to a current price of $38.17 — trading 407.6% above its estimated fair value. The current EV-to-EBITDA is -8.33. Celldex Therapeutics' overall GF Score™ is 57/100 with 8 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Celldex Therapeutics (CLDX), the current EV-to-EBITDA is -8.33 as of Jul. 15, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Celldex Therapeutics (CLDX) Overvalued in 2026?

Based on GuruFocus' analysis, Celldex Therapeutics stock appears to be overvalued. The current stock price of $38.17 is trading 407.6% above its estimated GF Value™ of $7.52. GuruFocus considers Celldex Therapeutics to be Significantly Overvalued.

Key valuation signals for CLDX:

  • EV-to-EBITDA: -8.33
  • GF Value™: $7.52 vs. price of $38.17 (407.6% above fair value)
  • GF Score™: 57/100 with 8 warning signs

No single metric tells the full story. See the CLDX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Celldex Therapeutics Business Description

Other Exchanges TCE2:Germany
Address 53 Frontage Road, Suite 220, Perryville III Building, Hampton, NJ, USA, 08827
Celldex Therapeutics Inc is a biopharmaceutical firm focused on mast cell biology and the development of therapeutic antibodies. Its pipeline includes monoclonal and bispecific antibodies aimed at treating severe inflammatory, allergic, autoimmune, and other mast cell-mediated diseases. The company operates in a single operating and reportable segment in the business of development, manufacturing and commercialization of novel therapeutics for human health care.
57GF Score

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EV-to-EBITDA is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$38.17
Price
$7.52
GF Value